Ultrasound-assisted synthesis of β-enaminone derivatives via Tin(Ⅳ)-catalyzed addition reaction from β-dicarbonyl compounds with nitriles

2021 ◽  
Vol 19 ◽  
Author(s):  
Shuchen Pei ◽  
Jinhua Yang ◽  
Jieyu Wang ◽  
Kangyao Yuan ◽  
Ziqiang Li
Keyword(s):  
Room Temperature ◽  
Addition Reaction ◽  
Ultrasound Irradiation ◽  
Irradiation Condition ◽  
Efficient Synthesis ◽  
Dicarbonyl Compounds ◽  
Ultrasound Assisted

Abstract: An efficient and eco-friendly approach for the synthesis of β-enaminone derivatives is described, which is through the addition of nitriles with β-dicarbonyl compounds under ultrasound irradiation condition at room temperature. The scope and limitation of this strategy are also discussed. A variety of substituted amides can be obtained in moderate to good yields. We hope that this protocol for the efficient synthesis of β-enaminones will offer insights in further investigations.

Ionic liquid promoted simple and efficient synthesis of β-enamino esters and β-enaminones from 1,3-dicarbonyl compounds – One-pot, three-component reaction for the synthesis of substituted pyridines

2005 ◽  
Vol 83 (10) ◽  
pp. 1746-1751 ◽  
Author(s):  
Ganesan Karthikeyan ◽  
Paramasivan T Perumal
Keyword(s):  
Ionic Liquid ◽  
Room Temperature ◽  
Ammonium Acetate ◽  
Efficient Synthesis ◽  
One Pot ◽  
Dicarbonyl Compounds ◽  
Acidic Ionic Liquid ◽  
Brønsted Acidic Ionic Liquid ◽  
Three Component Reaction ◽  
Substituted Pyridines

A facile enamination of 1,3-dicarbonyl compounds with amines has been developed that affords good to excellent yields of β-enamino esters and β-enaminones using Brønsted acidic ionic liquid 1-methylimidazolium trifluoroacetate ([Hmim]+Tfa–) at room temperature. This methodology has been extended for the synthesis of substituted pyridines in excellent yield by a one-pot, three-component reaction of 1,3-dicarbonyl compounds, ammonium acetate, and alkynone in the presence of [Hmim]+Tfa–.Key words: ionic liquid, β-enaminones, β-enamino esters, 1,3-dicarbonyl compounds, amines, pyridines.

An Efficient Ultrasound-assisted Method for the Synthesis of 1,4-Disubstituted Triazoles

2011 ◽  
Vol 66 (1) ◽  
pp. 77-82 ◽  
Author(s):  
Yuqin Jiang ◽  
Xiaolan Chen ◽  
Lingbo Qu ◽  
Junliang Wang ◽  
Jinwei Yuan ◽  
...  
Keyword(s):  
Efficient Method ◽  
Room Temperature ◽  
Ultrasound Irradiation ◽  
Ultrasound Assisted ◽  
High Yields ◽  
Optimized Conditions

An efficient method for the synthesis of 1,4-disubstituted triazoles has been developed with the help of ultrasound irradiation in water at room temperature. Under the optimized conditions, a novel series of 1,4-disubstituted 1,2,3-triazoles was synthesized in high yields

scholarly journals Ultrasound Assisted Green One Pot Synthesis of Bound Type bis-Heterocyclic furan-2-yl imidazo [1,2-a] Pyridines via GBBR

Proceedings ◽  
2018 ◽  
Vol 9 (1) ◽  
pp. 46 ◽  
Author(s):  
Mahanandaiah Kurva ◽  
Rocío Gámez-Montaño
Keyword(s):  
Ammonium Chloride ◽  
Room Temperature ◽  
Ultrasound Irradiation ◽  
One Pot ◽  
One Pot Synthesis ◽  
Ultrasound Assisted ◽  
Green Conditions

A series of six new 3-imidazo[1,2-a] pyridine furan bound type tris-heterocycles were synthesized by Ultrasound Irradiation (USI) assisted Groebke-Blackburn-Bienaymé reaction (GBBR), by employing ammonium chloride (10 mol%) as a catalyst in excellent yields (80–93%) under green conditions. This efficient and mild protocol has silent features such as green inexpensive and easily available catalyst and solvent at room temperature.

Ultrasound Assisted Cu(I) Catalyzed Aza-Michael Reactions in Water

2020 ◽  
Vol 5 (1) ◽  
pp. 36-39
Author(s):  
Ashok S. Pise ◽  
Arvind S. Burungale ◽  
Santosh S. Devkate
Keyword(s):  
Room Temperature ◽  
Reaction Rate ◽  
Ultrasound Irradiation ◽  
Unsaturated Esters ◽  
Michael Reactions ◽  
Amino Compounds ◽  
Ultrasound Assisted ◽  
Conventional Methods ◽  
High Yields

The β-amino compounds were synthesized from α,β-unsaturated esters, nitriles and amine using water as a solvent in the presence of 10 mol % Cu(I) catalyst in high yields within 2-5 min under ultrasound irradiation at room temperature. The reaction rate was enhanced tremendously under ultrasound irradiation as compared to conventional methods with improved yields have been recorded.

scholarly journals Synthesis of Network Polymers by Means of Addition Reactions of Multifunctional-Amine and Poly(ethylene glycol) Diglycidyl Ether or Diacrylate Compounds

Polymers ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 2047
Author(s):  
Naofumi Naga ◽  
Mitsusuke Sato ◽  
Kensuke Mori ◽  
Hassan Nageh ◽  
Tamaki Nakano
Keyword(s):  
Ethylene Glycol ◽  
Room Temperature ◽  
Addition Reaction ◽  
Monomer Concentration ◽  
Diglycidyl Ether ◽  
Porous Polymers ◽  
Addition Reactions ◽  
Poly Ethylene Glycol ◽  
Network Polymers ◽  
Poly Ethylene

Addition reactions of multi-functional amine, polyethylene imine (PEI) or diethylenetriamine (DETA), and poly(ethylene glycol) diglycidyl ether (PEGDE) or poly(ethylene glycol) diacrylate (PEGDA), have been investigated to obtain network polymers in H2O, dimethyl sulfoxide (DMSO), and ethanol (EtOH). Ring opening addition reaction of the multi-functional amine and PEGDE in H2O at room temperature or in DMSO at 90 °C using triphenylphosphine as a catalyst yielded gels. Aza-Michael addition reaction of the multi-functional amine and PEGDA in DMSO or EtOH at room temperature also yielded corresponding gels. Compression test of the gels obtained with PEI showed higher Young’s modulus than those with DETA. The reactions of the multi-functional amine and low molecular weight PEGDA in EtOH under the specific conditions yielded porous polymers induced by phase separation during the network formation. The morphology of the porous polymers could be controlled by the reaction conditions, especially monomer concentration and feed ratio of the multi-functional amine to PEGDA of the reaction system. The porous structure was formed by connected spheres or a co-continuous monolithic structure. The porous polymers were unbreakable by compression, and their Young’s modulus increased with the increase in the monomer concentration of the reaction systems. The porous polymers absorbed various solvents derived from high affinity between the polyethylene glycol units in the network structure and the solvents.

Efficient Synthesis of Tetrahydrobenzo[b]pyrans under Solvent‐Free Conditions at Room Temperature

2006 ◽  
Vol 36 (16) ◽  
pp. 2363-2369 ◽  
Author(s):  
Liangce Rong ◽  
Xiaoyue Li ◽  
Haiying Wang ◽  
Daqing Shi ◽  
Shujiang Tu ◽  
...  
Keyword(s):  
Room Temperature ◽  
Solvent Free ◽  
Efficient Synthesis ◽  
Solvent Free Conditions

ChemInform Abstract: An Efficient Synthesis of Isoxazoles and Pyrazoles under Ultrasound Irradiation.

ChemInform ◽  
2015 ◽  
Vol 46 (8) ◽  
pp. no-no
Author(s):  
Zhi-Bin Huang ◽  
Li-Li Li ◽  
Yan-Wei Zhao ◽  
Hui-Yuan Wang ◽  
Da-Qing Shi
Keyword(s):  
Ultrasound Irradiation ◽  
Efficient Synthesis
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