Application of Aptamer-based Hybrid Molecules in Early Diagnosis and Treatment of Diabetes Mellitus: From the Concepts Towards the Future

2019 ◽  
Vol 15 (4) ◽  
pp. 309-313 ◽  
Author(s):  
Sepideh Ahmadi ◽  
Navid Rabiee ◽  
Mohammad Rabiee
Keyword(s):  
Diabetes Mellitus ◽  
Early Diagnosis ◽  
Review Article ◽  
Diagnosis And Treatment ◽  
Future Perspective ◽  
Dna And Rna ◽  
Hybrid Molecules ◽  
Prevention And Treatment ◽  
Potential Factor ◽  
Treatment Of Diabetes

Aptamers have several positive advantages that made them eminent as a potential factor in diagnosing and treating diseases such as their application in prevention and treatment of diabetes. In this opinion-based mini-review article, we aimed to investigate the DNA and RNA-based hybrid molecules specifically aptamers and had a logical conclusion as a promising future perspective in early diagnosis and treatment of diabetes.

Dialysis Encephalopathy: A Review

1984 ◽  
Vol 13 (4) ◽  
pp. 309-326 ◽  
Author(s):  
Robert Jack ◽  
Pauline L. Rabin ◽  
T. Dwight McKinney
Keyword(s):  
Differential Diagnosis ◽  
Early Diagnosis ◽  
Case Studies ◽  
Health Personnel ◽  
Diagnosis And Treatment ◽  
Dialysis Encephalopathy ◽  
The Family ◽  
Prevention And Treatment ◽  
Salient Features

Dialysis encephalopathy (DE) is a distinct neuropsychiatric syndrome typically occurring in patients undergoing longterm hemodialysis. It is characterized by electroencephalographic abnormalities in association with disturbances of speech, cognition, movement, affect, or behavior. Previously thought to be relentlessly progressive, recent evidence linking the illness to aluminum overload has led to advances in prevention and treatment. Early diagnosis aids in the reversal or amelioration of the syndrome and can be of immense value to the patient, the family and involved health personnel. The general features of the syndrome, etiologic considerations, differential diagnosis and treatment are discussed. Three case studies are included to illustrate salient features of the syndrome.

COVID-19 WITH RHINO-ORBITO-CEREBRAL MUCORMYCOSIS : A SUDDEN SURGE

2021 ◽  
pp. 130-133
Author(s):  
Seema Patel ◽  
A. Z. Nitnaware ◽  
R. T. Pawar ◽  
Ashish Keche ◽  
Tanvi Rekhade
Keyword(s):  
Diabetes Mellitus ◽  
Early Diagnosis ◽  
Prospective Study ◽  
Previous History ◽  
Diagnosis And Treatment ◽  
Temporal Association ◽  
Concomitant Infection ◽  
History Of ◽  
A Prospective Study

Recently an increase in the incidence of mucormycosis is noticed in COVID-19 cases. The main aim of this study is to present our experience of rhino-orbito-cerebral mucormycosis in COVID-19 patients and thereby aid its early diagnosis and treatment. This is a prospective study of 12 cases diagnosed as Rhino-orbito-cerebral mucormycosis . Presentation of mucormycosis in COVID-19, their temporal association and outcome of treatment was studied. Pre-existing comorbidities were seen in 91.67% patients, Diabetes Mellitus (83.33%). Previous history of COVID-19 infection and treatment for the same in 41.67% cases, concomitant infection in 16.67% and asymptomatic undiagnosed covid (antibodies positive) was detected in 41.67%. All patients showed improvement in general and nasal condition (100%). Early diagnosis is must.

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