Use of Ultrasound to Observe Mycosis Fungoides: A Case Report and Review of Literature

2021 ◽  
Vol 17 ◽  
Author(s):  
Cong-Xian Chen ◽  
Jie Zhu ◽  
Zeng Zeng
Keyword(s):  
Case Report ◽  
T Cell ◽  
Mycosis Fungoides ◽  
Cell Lymphoma ◽  
Color Doppler ◽  
Clinical Manifestations ◽  
T Cell Lymphoma ◽  
Cutaneous T Cell Lymphoma ◽  
Erythematous Plaque ◽  
Doppler Image

Background: Mycosis fungoides (MF) is the most common form of cutaneous T-cell lymphoma with many clinicopathological variants, thus difficult to diagnose in its early stages. Case Presentation: This case report is about a 76 years old Chinese woman presented with 2 years history of erythematous plaque on the lateral right thigh, after combining clinical manifestations with results of pathological examinations, it is consistent with the diagnosis of MF. Discussion: Mycosis fungoides (MF) is the most common form of cutaneous T-cell lymphoma. Patient in this case had a long course of disease and repeated attacks. Ultrasound shows small patch of liquid dark area of the lesion. Color Doppler image shows rich blood flow which just looks like lacustrine. Thick and nourishing blood vessels could be seen in the depth. Conclusion: Our case report using ultrasound to observe MF and demonstrate that ultrasound is helpful in diagnosing and evaluating effectiveness in treating MF.

Woringer-Kolopp Disease of the Foot: A Case Report

2020 ◽  
Vol 110 (6) ◽  
Author(s):  
James J. LaPolla ◽  
Lawrence A. DiDomenico ◽  
Robert T. Brodell ◽  
Michael L. Casteel
Keyword(s):  
Case Report ◽  
T Cell ◽  
Mycosis Fungoides ◽  
Rare Variant ◽  
Cell Lymphoma ◽  
Treatment Options ◽  
T Cell Lymphoma ◽  
Cutaneous T Cell Lymphoma ◽  
Review Of The Literature ◽  
Intralesional Steroids

Woringer-Kolopp disease is a rare variant of mycosis fungoides, a type of cutaneous T-cell lymphoma. Described is a case of a small annular plaque on the foot diagnosed histologically as Woringer-Kolopp disease and treated successfully with topical and intralesional steroids. In addition, a brief review of the literature and treatment options is provided.

scholarly journals PRO25 Healthcare Resource Use in Mycosis Fungoides-Type Cutaneous T-Cell Lymphoma: Results from a UK-Based Clinician Questionnaire

2020 ◽  
Vol 23 ◽  
pp. S693-S694
Author(s):  
J. Scarisbrick ◽  
F. Schmidt ◽  
M.M. Turini ◽  
P. D'agostino ◽  
D. Summers ◽  
...  
Keyword(s):  
T Cell ◽  
Mycosis Fungoides ◽  
Resource Use ◽  
Healthcare Resource ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Cutaneous T Cell Lymphoma ◽  
Healthcare Resource Use

Cutaneous T-Cell Lymphoma: Mycosis Fungoides and Sézary Syndrome

2019 ◽  
pp. 221-246
Author(s):  
Timothy J. Voorhees ◽  
Edith V. Bowers ◽  
Christopher R. Kelsey ◽  
Yara Park ◽  
Anne W. Beaven
Keyword(s):  
T Cell ◽  
Mycosis Fungoides ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Sézary Syndrome ◽  
Sezary Syndrome ◽  
Cutaneous T Cell Lymphoma

scholarly journals Demonstration of antibodies to human T-cell lymphotropic virus-I tax in patients with the cutaneous T-cell lymphoma, mycosis fungoides, who are seronegative for antibodies to the structural proteins of the virus

Blood ◽  
1996 ◽  
Vol 88 (8) ◽  
pp. 3004-3009 ◽  
Author(s):  
BA Pancake ◽  
EH Wassef ◽  
D Zucker-Franklin
Keyword(s):  
T Cell ◽  
Mycosis Fungoides ◽  
Mononuclear Cells ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Structural Proteins ◽  
Infected Cell Line ◽  
Cutaneous T Cell Lymphoma ◽  
Serologic Tests ◽  
Human T Cell

Although most patients with the cutaneous T-cell lymphoma, mycosis fungoides (MF), are seronegative for human T-cell lymphotropic virus-I or -II (HTLV-I/II) when tested by assays that measure only antibodies to the viral structural proteins, the majority of such patients harbor HTLV-I-related pol and tax proviral sequences that encode proteins not included in routinely used serologic tests. Tax mRNA has also been detected in their peripheral blood mononuclear cells (PBMC). Therefore, it seemed possible that these patients have antibodies to the tax protein. To investigate this, enzyme-linked immunosorbent assays (ELI-SAs) and Western blot assays were set up, using as antigens the full-length HTLV-I tax cloned from the prototypic HTLV-I-infected cell line, C91PL, and from PBMC of a MF patient, as well as a synthetic peptide made to the carboxy-terminal 20 amino acids of tax-I. Of 60 MF patients whose PBMC were shown to be positive for tax proviral DNA and mRNA, 50 (83%) were shown to have tax antibodies. The antigen derived from the MF patient was most useful in detecting such antibodies. These results demonstrate the need for including other HTLV-related antigens in addition to gag and env in serologic tests used to identify HTLV-infected individuals. The findings underscore the fact that individuals considered seronegative on the basis of currently used tests can be infected with HTLV.

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