scholarly journals Platelet Rich Fibrin in Periodontal Regeneration

2016 ◽  
Vol 10 (1) ◽  
pp. 174-181 ◽  
Author(s):  
Muthukumaraswamy Arunachalam ◽  
Shaju J. Pulikkotil ◽  
Nath Sonia

Periodontitis is a chronic bacterial infection resulting in destruction of the supporting structures of the teeth. Regeneration of the lost tissues has faced difficulties primarily due to the lack of support during the intricate healing processes. A surgical additive which can ‘jump start’ the healing process to a more predictable regenerative process is always on the wish list of any periodontist. Platelet-rich fibrin (PRF) is a second generation platelet concentrate that has been considered to be an important, easy to obtain, predictable surgical additive for periodontal regeneration. This autologous scaffold provides the much needed bio-chemical mediators which has the potential for enhancing reconstruction of the periodontium. This review article tries to understand as to why PRF would be an important link to reach predictable periodontal regeneration.

2021 ◽  
Vol 3 (3) ◽  
pp. 99-101
Author(s):  
Prashanti Wahengbam ◽  
Nenavata Ravi ◽  
S Bharathesh ◽  
Dimple Budhiraja ◽  
Neha Nandal ◽  
...  

Platelet rich fibrin is a part of platelet concentrate, that is derived from human blood and made through the process of centrifugation. It is an autogeneous bio material, which basically constitutes various growth factors, and cytokines that are entrapped in its matrix of fibrin. Platelet rich fibrin provides ideal environment for healing of the wound and the regeneration of the tissue. Platelet rich fibrin helps in regulating the inflammation process and increases the healing process.


2016 ◽  
Vol 7 (1) ◽  
Author(s):  
Nenad Tanasković

Platelet Rich Fibrin (PRF) is autologous biomaterial which is the second-generation platelet concentrate. It has a favorable biological properties that accelerate healing of soft tissue, and bone, giveing a wide range of applications found in oral and maxillofacial surgery and other surgical fields. PRF technique was developed by Choukroun et al in 2001 and it represents a second generation of autologous platelet concentrate, which is used to accelerate the healing of soft and hard tissue. In contrast to the PRP, the PRF is composed of autologous fibrin matrix in which a large amount of platelets and their growth factors are embedded. PRF-graft is used in augmentative techniques residual bone defects, alone or in combination with biomaterials. When the alveolar ridge augmentation technique GBR, the PRF membranes can be used for protection and stabilization of bone compensation. PRF accelerates the healing of soft tissue and reduces the possibility of dehiscence and exposure of the membrane.


Author(s):  
David M. Dohan ◽  
Joseph Choukroun ◽  
Antoine Diss ◽  
Steve L. Dohan ◽  
Anthony J.J. Dohan ◽  
...  

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