scholarly journals USE OF PLATELET-RICH FIBRIN IN MAXILLOFACIAL SURGERY

2016 ◽  
Vol 7 (1) ◽  
Author(s):  
Nenad Tanasković
Keyword(s):  
Soft Tissue ◽  
Second Generation ◽  
Maxillofacial Surgery ◽  
Biological Properties ◽  
Platelet Concentrate ◽  
Oral And Maxillofacial Surgery ◽  
Platelet Rich Fibrin ◽  
Ridge Augmentation ◽  
Wide Range ◽  
Autologous Platelet Concentrate

Platelet Rich Fibrin (PRF) is autologous biomaterial which is the second-generation platelet concentrate. It has a favorable biological properties that accelerate healing of soft tissue, and bone, giveing a wide range of applications found in oral and maxillofacial surgery and other surgical fields. PRF technique was developed by Choukroun et al in 2001 and it represents a second generation of autologous platelet concentrate, which is used to accelerate the healing of soft and hard tissue. In contrast to the PRP, the PRF is composed of autologous fibrin matrix in which a large amount of platelets and their growth factors are embedded. PRF-graft is used in augmentative techniques residual bone defects, alone or in combination with biomaterials. When the alveolar ridge augmentation technique GBR, the PRF membranes can be used for protection and stabilization of bone compensation. PRF accelerates the healing of soft tissue and reduces the possibility of dehiscence and exposure of the membrane.

Use of Platelet-Rich Plasma and Platelet-Rich Fibrin in Dentistry and Oral Surgery: Introduction and Review of the Literature

2019 ◽  
Vol 36 (2) ◽  
pp. 109-123 ◽  
Author(s):  
Kristina Feigin ◽  
Bonnie Shope
Keyword(s):  
Soft Tissues ◽  
Oral Surgery ◽  
Platelet Rich Plasma ◽  
Maxillofacial Surgery ◽  
Oral And Maxillofacial Surgery ◽  
Platelet Concentrates ◽  
Platelet Rich Fibrin ◽  
Wide Range ◽  
Comprehensive Examination ◽  
And Function

Platelet concentrates, mostly represented by platelet-rich plasma and platelet-rich fibrin, have gained significant interest in various medical and oral disciplines because of their potential to stimulate and boost regeneration of hard and soft tissues. Prepared from the patient’s own blood, they have been tested and used in various different surgical fields including oral and maxillofacial surgery. The effects of these biomaterials are described to be a result of the large concentration of platelets which contain a wide range of growth factors. The aim of this article is to introduce the principle and function of these platelet concentrates, to review their preparation, and to provide a comprehensive examination of the published oral and maxillofacial literature on this subject.

COMPARISON OF POST EXTRACTION SOCKET HEALING WITH AND WITHOUT USING PLATELET RICH FIBRIN (PRF) – A CLINICAL AND RADIOGRAPHIC STUDY

2021 ◽  
pp. 62-65
Author(s):  
S.P. Indra Kumar ◽  
Kavin T ◽  
Narendar R ◽  
E. Gayathri Priyadharshini ◽  
Akshaya murugan ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Maxillofacial Surgery ◽  
Test Group ◽  
Control Group ◽  
Oral And Maxillofacial Surgery ◽  
Soft Tissue Healing ◽  
Extraction Socket ◽  
Platelet Rich Fibrin ◽  
Tissue Healing ◽  
Socket Healing

AIM: The aim of this study is to comparatively evaluate the post extraction socket healing clinically and radiographically with and without using Platelet Rich Fibrin (PRF). MATERIALS AND METHODS: Fifty, otherwise healthy individuals undergoing dental treatment in the department of Oral and Maxillofacial surgery, Vivekananda Dental College for women, Thiruchengode, were randomly selected and the participants were divided into two groups – test group(PRF, n=25) and control group (Blood clot, n=25). Blood was freshly obtained from the participants of the test group and PRF was prepared. PRF was placed in the sockets of the test group and followed by the pressure application and suturing. Control group were allowed to heal naturally. Clinically, soft tissue healing and socket closure were assessed. Radiographic analysis of socket healing done by comparison of pre- and post-operative radiographs. The clinical follow-up assessments were done at an interval of 3 days, 1 week and 4 weeks and the data obtained were assessed. The patients were aged above 18 years, i RESULT: ncluding 33 females and 17 males. The soft tissue and socket healing were higher in the test group when compared with the control group clinically and the mean proportion of radiographic bone ll was signicantly higher in the test group in all the time intervals of 3 days, 1 week and 4 weeks, respectively. Outcome of the study CONCLUSION: demonstrate that the PRF placement in the extraction socket accelerates soft tissue healing and socket healing and increases the bone ll and reduces the bone resorption using clinical and radiographic methods.

Fifteen Years of Platelet Rich Fibrin in Dentistry and Oromaxillofacial Surgery: How High is the Level of Scientific Evidence?

2018 ◽  
Vol 44 (6) ◽  
pp. 471-492 ◽  
Author(s):  
Shahram Ghanaati ◽  
Carlos Herrera-Vizcaino ◽  
Sarah Al-Maawi ◽  
Jonas Lorenz ◽  
Richard J Miron ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Tissue Regeneration ◽  
Scientific Evidence ◽  
Maxillofacial Surgery ◽  
Socket Preservation ◽  
Platelet Rich Fibrin ◽  
Scientific Level ◽  
Ridge Augmentation ◽  
Soft Tissue Regeneration ◽  
Published Evidence

Platelet-rich fibrin is a blood concentrate system used for soft tissue and bone tissue regeneration. In the last decade, platelet rich fibrin (PRF) has been widely used in different indication fields, particularly in oral and maxillofacial surgery. This review investigates the level of scientific evidence of published articles related to the use of PRF for bone and soft tissue regeneration in dentistry and maxillofacial surgery. An electronic literature research using the biomedical search engine “National Library of Medicine” (PubMed-MEDLINE) was performed in May 2017. A total of 392 articles were found, 72 of which were classified for each indication field. When comparing PRF with biomaterials vs biomaterial alone in sinus lift (5 studies; IIa), no statistically significant differences were detected. Socket preservation and ridge augmentation using PRF significantly enhanced new bone formation compared to healing without PRF (7 studies Ib, IIa, IIb). Reepithelialization and bone regeneration was achieved in 96 of 101 patients diagnosed with medication-related osteonecrosis of the jaw (5 studies, III). In periodontology, PRF alone (6 studies; Ib, IIa, IIb) or its combination with biomaterials (6 studies; Ib, IIa, IIb) significantly improved the pocket depth and attachment loss compared to a treatment without PRF. Over 70% of the patients were part of studies with a high level of scientific evidence (randomized and controlled prospective studies). This published evidence (38 articles), with a high scientific level, showed that PRF is a beneficial tool that significantly improves bone and soft tissue regeneration. However, the clinical community requires a standardization of PRF protocols to further examine the benefit of PRF in bone and soft tissue regeneration in reproducible studies, with a higher scientific level of evidence.

scholarly journals Interrelation between facial soft tissue lessions, underlying fracture patterns and treatment of zygomatic bone trauma: a 10 year retrospective study

2020 ◽  
Author(s):  
Juncar Raluca Iulia ◽  
Paul Andrei Tent ◽  
Juncar Mihai ◽  
Arghir Ioan Anton ◽  
Arghir Cristina Oana ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Bone Fractures ◽  
Maxillofacial Surgery ◽  
Fracture Pattern ◽  
Oral And Maxillofacial Surgery ◽  
Facial Soft Tissue ◽  
Nominal Data ◽  
Correct Treatment ◽  
Zygomatic Bone ◽  
Zygomatic Fracture

Abstract Background: The pattern of zygomatic bone fractures varies in the literature, their features being frequently masked by the presence of associated soft tissue lesions. In this context the clinical diagnosis and the therapeutic indications can be difficult. The aim of this study was to evaluate the clinical features of zygomatic bone fractures and their interrelation with concomitant overlying soft tissue injuries, as well as to assess the type of treatment methods applied depending on the fracture pattern and the results achieved depending on the incidence rate of postoperative complications. We will use these results in order to improve the diagnosis and the establishment of correct treatment of this pathology. Methods: A 10-year retrospective evaluation of midface fractures was performed in patients diagnosed and treated in a tertiary Clinic of Oral and Maxillofacial Surgery. Statistical analysis was performed with the MedCalc Statistical Software version 19.2 (MedCalc Software bvba, Ostend, Belgium;53 https://www.medcalc.org; 2020). Nominal data were expressed as frequency and percentage. The comparisons of the frequencies of a nominal variable among the categories of another nominal variable were made using the chi-square test. Multivariate logistic regressions were used in order to establish the independent association between variables and lacerations/excoriations. After using the Bonferroni correction for multiple comparisons, a value of p<0.025 was considered statistically significant.Results: The study included 242 patients with zygomatic bone fractures. The majority of the fractures were displaced n=179 (73.9%), closed n=179 (73.9%) and complete n=219 (90.5%). Hematoma was the most frequent associated soft tissue lesion n=102 (42.1%) regardless of the fracture pattern (p=1.000). Complete zygomatic fracture (OR – 2.68; p=0.035) and fractures with displacement (OR – 3.66; p=0.012) were independently associated with the presence of laceration. Fractures with displacement (OR – 7.1; p=0.003) were independently associated with the presence of excoriation. The most frequent type of treatment applied was Gillies reduction (61.9%), followed by ORIF (30.9%). The most frequent postoperative complication was malunion secondary to Gillies treatment (4,6%). Conclusions: Patients presenting lacerations and excoriations on clinical soft tissue examination will most frequently have an underlying complete, displaced or comminuted zygomatic fracture. In the case of displaced, open or comminuted fractures we achieved the best results secondary to ORIF treatment method, while in the case of non-displaced and closed fractures, the best results achieved were secondary to conservative treatment.

scholarly journals Utility of Photodynamic Therapy in Dentistry: Current Concepts

2020 ◽  
Vol 8 (2) ◽  
pp. 43
Author(s):  
Anette Stájer ◽  
Szilvia Kajári ◽  
Márió Gajdács ◽  
Aima Musah-Eroje ◽  
Zoltán Baráth
Keyword(s):  
Photodynamic Therapy ◽  
Clinical Success ◽  
Maxillofacial Surgery ◽  
Treatment Method ◽  
Treatment Modalities ◽  
Oral And Maxillofacial Surgery ◽  
Invasive Treatment ◽  
Advantages And Disadvantages ◽  
Non Invasive ◽  
Wide Range

The significant growth in scientific and technological advancements within the field of dentistry has resulted in a wide range of novel treatment modalities for dentists to use. Photodynamic therapy (PDT) is an emerging, non-invasive treatment method, involving photosensitizers, light of a specific wavelength and the generation of singlet oxygen and reactive oxygen species (ROS) to eliminate unwanted eukaryotic cells (e.g., malignancies in the oral cavity) or pathogenic microorganisms. The aim of this review article is to summarize the history, general concepts, advantages and disadvantages of PDT and to provide examples for current indications of PDT in various subspecialties of dentistry (oral and maxillofacial surgery, oral medicine, endodontics, preventive dentistry, periodontology and implantology), in addition to presenting some images from our own experiences about the clinical success with PDT.

scholarly journals Diode laser in the surgical treatment of inflammatory fibrous hyperplasia: Case report and literature review

2018 ◽  
Vol 32 (3) ◽  
pp. 154
Author(s):  
Fernando De Oliveira Andriola ◽  
Leonardo Matos Santolim Zanettini ◽  
Ricardo Giacomini De Marco ◽  
Camila Kunz ◽  
Cássia Dos Santos Machado Vaz ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Diode Laser ◽  
Oral Surgery ◽  
Maxillofacial Surgery ◽  
Complete Healing ◽  
Oral And Maxillofacial Surgery ◽  
Surgical Removal ◽  
Tissue Mass ◽  
Patient Reported ◽  
School Of Dentistry

OBJECTIVE: This article presents a case of inflammatory fibrous hyperplasia (IFH) treated by diode laser surgery, as well as a review of the literature about this pathology.CASE DESCRIPTION: A 55-year-old woman was referred to the Department of Oral and Maxillofacial Surgery, Pontifical Catholic University of Rio Grande do Sul, School of Dentistry, complaining of a discomfort on swallowing due to a soft-tissue mass in the oral cavity that had been developing for approximately 3 years. Intraoral examination revealed multiple exophytic, pedunculated lesions with a smooth surface and pinkish in color, affecting almost the entire right cheek mucosa. The lesion turned out to be a IFH by histopatology. Surgical removal of IFH of the oral mucosa using a diode laser was performed. The lesion was removed in 3 sessions. The patient reported no local symptoms after each irradiation. The clinical appearance 10 months after the last irradiation session demonstrated complete healing and no signals of recurrence.CONCLUSION: Based on the results obtained, we can conclude that diode laser radiation contributes significantly to the advancement of oral surgery and should be considered a valuable resource for the treatment of soft-tissue lesions in the field of oral and maxillofacial surgery.

scholarly journals Additive Manufacturing: A 3-Dimensional Approach in Periodontics

2020 ◽  
pp. 105-117
Author(s):  
Anurag Bhatnagar ◽  
Amit Bhardwaj ◽  
Shalu Verma
Keyword(s):  
Additive Manufacturing ◽  
Maxillofacial Surgery ◽  
Oral And Maxillofacial Surgery ◽  
Layer By Layer ◽  
Additive Technology ◽  
3 Dimensional ◽  
Ridge Augmentation ◽  
Drug Technology ◽  
Dimensional Printing

Additive manufacturing technology or 3-dimensional printing has been used since ages in various fields including medical. Their addition to dentistry is recent and has tried to revolutionize the field. It is being used in various fields of dentistry like endodontics, prosthodontics, orthodontics, oral and maxillofacial surgery and recently in periodontics and Implantology. With introduction of recent “layer-by-layer” additive technology, their use in periodontal field has changed its treatment planning. It is use in preparation of customized scaffold with or without stem cell therapy, ridge augmentation, sinus lift and guided implant surgery, implant fixtures, education models, drug technology and many more. This review has tried to explain the various applications of the additive manufacturing in the field of periodontics with recent evidences. This paper highlights the role of 3-dimensional printing which can change the future of periodontal management.   

scholarly journals Future dental device- 3-dimensional printing approach in dentistry

2021 ◽  
Vol 7 (2) ◽  
pp. 37-47
Author(s):  
Deepak Grover ◽  
Navneet Kaur ◽  
Gurpreet Kaur
Keyword(s):  
Maxillofacial Surgery ◽  
Three Dimensional ◽  
Cost Effective ◽  
Physical Models ◽  
Advanced Technology ◽  
Oral And Maxillofacial Surgery ◽  
3 Dimensional ◽  
Ridge Augmentation ◽  
Surgical Guides ◽  
Dimensional Printing

The three-dimensional printing has been used since very long ago in the field of medicine as well as in dentistry. The evolution of 3-dimensional imaging and modelling in dentistry is progressing towards a more efficient and cost-effective workflow using state-of-the-art technology. The practicability of this technique is expanding in several dental fields such as prosthodontics, oral and maxillofacial surgery and prosthesis, and production of surgical guides or physical models in dental implant treatment. The key of success in this technique depends on the usage of various materials such as, metal, resin, plastic etc. which is most commonly used in dentistry. With introduction of this recent advanced technology, it is used in various surgical procedures such as ridge augmentation, sinus lift and guided implant surgery, implant fixtures, preparation of customized scaffold with or without stem cell therapy, education models as well as in drug delivery technology. The 3-dimensional printing technology is becoming more economical technique and able to produce replica of dental models with a high resolution and accuracy.

scholarly journals The 3 R’s for Platelet-Rich Fibrin: A “Super” Tri-Dimensional Biomaterial for Contemporary Naturally-Guided Oro-Maxillo-Facial Soft and Hard Tissue Repair, Reconstruction and Regeneration

Materials ◽  
2018 ◽  
Vol 11 (8) ◽  
pp. 1293 ◽  
Author(s):  
Consuelo Zumarán ◽  
Marcelo Parra ◽  
Sergio Olate ◽  
Eduardo Fernández ◽  
Francisco Muñoz ◽  
...  
Keyword(s):  
Tissue Repair ◽  
Oral Surgery ◽  
Therapeutic Potential ◽  
Maxillofacial Surgery ◽  
Clinical Effectiveness ◽  
Oral And Maxillofacial Surgery ◽  
User Friendliness ◽  
Platelet Rich Fibrin ◽  
Tissue Repair And Regeneration ◽  
Regenerative Dentistry

Platelet-Rich fibrin (PRF) is a three-dimensional (3-D) autogenous biomaterial obtained via simple and rapid centrifugation from the patient’s whole blood samples, without including anti-coagulants, bovine thrombin, additives, or any gelifying agents. At the moment, it is safe to say that in oral and maxillofacial surgery, PRFs (particularly, the pure platelet-rich fibrin or P-PRF and leukocyte and platelet-rich fibrin or L-PRF sub-families) are receiving the most attention, essentially because of their simplicity, cost-effectiveness, and user-friendliness/malleability; they are a fairly new “revolutionary” step in second-generation therapies based on platelet concentration, indeed. Yet, the clinical effectiveness of such surgical adjuvants or regenerative platelet concentrate-based preparations continues to be highly debatable, primarily as a result of preparation protocol variability, limited evidence-based clinical literature, and/or poor understanding of bio-components and clinico-mechanical properties. To provide a practical update on the application of PRFs during oral surgery procedures, this critical review focuses on evidence obtained from human randomized and controlled clinical trials only. The aim is to serve the reader with current information on the clinical potential, limitations, challenges, and prospects of PRFs. Accordingly, reports often associate autologous PRFs with early bone formation and maturation; accelerated soft-tissue healing; and reduced post-surgical edema, pain, and discomfort. An advanced and original tool in regenerative dentistry, PRFs present a strong alternative and presumably cost-effective biomaterial for oro-maxillo-facial tissue (soft and hard) repair and regeneration. Yet, preparation protocols continue to be a source of confusion, thereby requiring revision and standardization. Moreover, to increase the validity, comprehension, and therapeutic potential of the reported findings or observations, a decent analysis of the mechanico-rheological properties, bio-components, and their bioactive function is eagerly needed and awaited; afterwards, the field can progress toward a brand-new era of “super” oro-dental biomaterials and bioscaffolds for use in oral and maxillofacial tissue repair and regeneration, and beyond.

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