A Case of Infrapatellar Fat Pad Ganglion of the Knee

Introduction: A ganglion cyst can induce symptoms around the knee and should be considered as an intra-articular mass in differential diagnosis. Case Presentation: A 22-year-old female presented with a persistent medial knee joint pain in her left knee for 2 years. There was soft tissue swelling on the anteromedial aspect of the infrapatellar region on her left knee. Lachman and McMurray tests were negative. MRI showed a multilobular cyst in the infrapatellar fat pad with T1 low intensity and T2 STIR high intensity. The cyst was not attached to either meniscus. ACL and PCL looked normal. During surgery, the cyst was found to arise from the intra-patellar fat pad and was not attached to the menisci or synovium. The cyst was completely resected. Histological findings showed a multilobular cyst with a glassy fibrous tissue wall and clear jelly-like consistency, confirming the diagnosis of a ganglion. The patient recovered asymptomatically and has been without recurrence 7 years postoperatively. Conclusion: Differential diagnoses of an infrapatellar swelling are a meniscal cyst, synovial cyst, or ganglion. Most cases of cysts around the knee generate from fluid collection through meniscal tears. A ganglion cyst is a synovium-lined structure and is common around the wrist joint, but rare in the knee joint. A ganglion cyst in the knee joint often arises from ACL or PCL, but rarely arises from the infrapatellar fat pad. A ganglion cyst is one of the differential diagnoses of parameniscal cysts around the knee. We recommended an open resection with arthroscopic examination.

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Localized Giant Cell Tenosynovial Tumor Seen in the Knee Joint

Case Reports in Orthopedics ◽

10.1155/2014/840243 ◽

2014 ◽

Vol 2014 ◽

pp. 1-3

Author(s):

Ozan Beytemür ◽

Cem Albay ◽

Ümit Seza Tetikkurt ◽

Mehmet Öncü ◽

Mehmet Ali Baran ◽

...

Keyword(s):

Knee Joint ◽

Giant Cell ◽

Fibrous Tissue ◽

Cell Tumor ◽

Infrapatellar Fat Pad ◽

Fat Pad ◽

Tenosynovial Giant Cell Tumor ◽

Marginal Excision ◽

Aggressive Tumor ◽

Localized Form

Tenosynovial giant cell tumor is a locally aggressive tumor arising from the synovia of the fibrous tissue surrounding the joints, tendon sheaths, mucosal bursas, and tendons. Although it is often to be observed at the hand, localized form is very rare in the knee joint. In this case report, we aimed to present a very rare case of a surgically treated intra-articular giant cell tenosynovial tumor arising from the hoffa’s infrapatellar fat pad of a 19-year-old male patient, by reviewing the literature. The patient we have treated with marginal excision was asymptomatic at the 14th month in the controls and recurrence was not detected.

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Unusual presentation of giant ganglion cyst from the infrapatellar (Hoffa’s) fat pad of knee: a case report

International Journal of Research in Orthopaedics ◽

10.18203/issn.2455-4510.intjresorthop20205579 ◽

2020 ◽

Vol 7 (1) ◽

pp. 153

Author(s):

A. M. Shantha kumar ◽

Santosh Sahanand ◽

David V. Rajan

Keyword(s):

Case Report ◽

Knee Joint ◽

Patellar Tendon ◽

Treatment Option ◽

Ganglion Cyst ◽

Posterior Wall ◽

Infrapatellar Fat Pad ◽

Fat Pad ◽

Hoffa’S Fat Pad ◽

Open Excision

<p>Ganglion cyst of the knee joint can be intra articular or extra articular. Large intra articular ganglionic cystic formations arising from the infrapatellar fat pad are quite uncommon and only few are reported. Treatment option is surgery(open/arthroscopic) depending on the site and size of the cyst. We report a case of giant ganglion cyst arising from the infra patellar Hoffa's fat pad which presents anterior to the patellar tendon through a rent in the medial retinaculum with the posterior wall of the cyst being adherent to the para tenon of the patellar tendon, in a 58 year old male which presents anterior to the patellar tendon through a rent in the patellar retinaculum which was adherent to the para tenon of the patellar tendon and it was managed by open excision of the cyst.</p><p> </p>

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Phosphorus Concentration in Knee Joint Structures of Patients Following Replacement Surgery

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph16040525 ◽

2019 ◽

Vol 16 (4) ◽

pp. 525 ◽

Cited By ~ 1

Author(s):

Ciosek Żaneta ◽

Kosik-Bogacka Danuta ◽

Łanocha-Arendarczyk Natalia ◽

Kot Karolina ◽

Karaczun Maciej ◽

...

Keyword(s):

Knee Joint ◽

Cruciate Ligament ◽

The Body ◽

Infrapatellar Fat Pad ◽

Emission Spectrometry ◽

Phosphorus Concentration ◽

Spongy Bone ◽

Fat Pad ◽

Hoffa’S Fat Pad ◽

P Concentration

The aim of the study was to assess phosphorus (P) concentration in structures of the knee joint—including the tibial spongy bone, articular cartilage, meniscus, anterior cruciate ligament, and infrapatellar fat pad (Hoffa’s fat pad)—of patients following knee joint replacement. The study also aimed to assess the influence of selected biological and environmental factors on P concentration in studied parts of the knee joint. Phosphorus concentration was determined using inductively coupled plasma-atomic emission spectrometry (ICP-AES). Statistically significant differences in P concentration were found between different elements of the knee joint. The highest P concentration was measured in the spongy bone (72,746.68 mg kg−1 dw) and the lowest in the Hoffa’s fat pad (1203.19 mg kg−1 dw). P levels were unaffected by gender, age, BMI, place of residence, smoking, or alcohol consumption. Data on P concentration in the osteoarticular elements of the knee may be useful in the interpretation and evaluation of biochemical, morphological, and mechanical changes occurring in the body.

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Endoscopic excision of a ganglion cyst in an infrapatellar fat pad extending into the subcutaneous layer

Journal of Orthopaedic Science ◽

10.1007/s00776-011-0099-2 ◽

2012 ◽

Vol 17 (5) ◽

pp. 654-658 ◽

Cited By ~ 2

Author(s):

Hong-Chul Lim ◽

Hak-Jun Kim ◽

Yoon-Jung Kim ◽

Jae-Hyuk Yang ◽

Taik-Sun Kim ◽

...

Keyword(s):

Ganglion Cyst ◽

Infrapatellar Fat Pad ◽

Fat Pad ◽

Endoscopic Excision ◽

Subcutaneous Layer

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Induction of chondrogenesis and expression of superficial zone protein (SZP)/lubricin by mesenchymal progenitors in the infrapatellar fat pad of the knee joint treated with TGF-β1 and BMP-7

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2008.08.138 ◽

2008 ◽

Vol 376 (1) ◽

pp. 148-153 ◽

Cited By ~ 55

Author(s):

Sang Yang Lee ◽

Toshiyuki Nakagawa ◽

A. Hari Reddi

Keyword(s):

Knee Joint ◽

Infrapatellar Fat Pad ◽

Fat Pad ◽

Superficial Zone ◽

Mesenchymal Progenitors ◽

Superficial Zone Protein ◽

Tgf Β1

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Factors Affecting the Aluminum, Arsenic, Cadmium and Lead Concentrations in the Knee Joint Structures

Frontiers in Public Health ◽

10.3389/fpubh.2021.758074 ◽

2021 ◽

Vol 9 ◽

Author(s):

Guoyong Li ◽

Chunfeng Xiong ◽

Wenhua Xu ◽

Runhong Mei ◽

Tao Cheng ◽

...

Keyword(s):

Knee Joint ◽

Cancellous Bone ◽

Toxic Elements ◽

Cruciate Ligament ◽

Toxic Element ◽

Infrapatellar Fat Pad ◽

Diabetic Patients ◽

Fat Pad ◽

Femoral Cartilage ◽

Anterior Cruciate

Background: Toxic elements, such as aluminum (Al), arsenic (As), cadmium (Cd), and lead (Pb), are persistent environmental pollutants that can cause adverse effects on the health of exposed individuals. Bone is one of the primary target organs of accumulation and potential damage from toxic elements.Objectives: This study was performed to determine the Al, As, Cd, and Pb concentrations in the femoral cancellous bone, femoral cartilage, anterior cruciate ligament, meniscus, tibial cartilage, tibial cancellous bone and infrapatellar fat pad. Furthermore, the aim of this study was to explore the relationships between toxic element concentrations and related factors such as gender, age, place of residence, hypertension and diabetes, and to determine the correlations among these toxic elements in knee joint structures.Methods: The samples used this study were collected from 51 patients following total knee arthroplasty. The Al, As, Cd, and Pb concentrations were determined using inductively coupled plasma optic emission spectrometry.Results: Significant differences were found in the Al, As, Cd, and Pb concentrations among the knee joint structures. Cd concentration in the tibial cancellous bone in women was significantly higher than in men. Pb concentration in the infrapatellar fat pad of urban patients was significantly higher as compared to rural patients. Al concentrations in the femoral cancellous bone, femoral cartilage, anterior cruciate ligament, meniscus and tibial cartilage were significantly higher in patients living in urban areas than in rural areas. As concentration in the tibial cancellous bone of diabetic patients was significantly higher compared to non-diabetic patients. In addition, significant Spearman's positive correlations were found between Al and Pb in the knee joint structures.Conclusion: The obtained results of the investigated toxic elements may serve as a basis for establishing the reference values of Al, As, Cd, and Pb in the knee joint structures. The results reported in the study provides novel data regarding the relationships between the toxic element concentrations and gender, age, place of residence, hypertension and diabetes in the studied structures of knee joint. Furthermore, new interactions among these toxic elements were noted.

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Degenerative joint disease induced by repeated intra-articular injections of monosodium urate crystals in rats as investigated by translational imaging

Scientific Reports ◽

10.1038/s41598-021-04125-7 ◽

2022 ◽

Vol 12 (1) ◽

Author(s):

Nathalie Accart ◽

Janet Dawson ◽

Michael Obrecht ◽

Christian Lambert ◽

Manuela Flueckiger ◽

...

Keyword(s):

Knee Joint ◽

Inflammatory Cells ◽

Cyst Formation ◽

Degenerative Joint Disease ◽

Joint Disease ◽

Infrapatellar Fat Pad ◽

Monosodium Urate ◽

Fat Pad ◽

Crystal Deposition ◽

Translational Imaging

AbstractThe objective of this work was to assess the consequences of repeated intra-articular injection of monosodium urate (MSU) crystals with inflammasome priming by lipopolysaccharide (LPS) in order to simulate recurrent bouts of gout in rats. Translational imaging was applied to simultaneously detect and quantify injury in different areas of the knee joint. MSU/LPS induced joint swelling, synovial membrane thickening, fibrosis of the infrapatellar fat pad, tidemark breaching, and cartilage invasion by inflammatory cells. A higher sensitivity to mechanical stimulus was detected in paws of limbs receiving MSU/LPS compared to saline-injected limbs. In MSU/LPS-challenged joints, magnetic resonance imaging (MRI) revealed increased synovial fluid volume in the posterior region of the joint, alterations in the infrapatellar fat pad reflecting a progressive decrease of fat volume and fibrosis formation, and a significant increase in the relaxation time T2 in femoral cartilage, consistent with a reduction of proteoglycan content. MRI also showed cyst formation in the tibia, femur remodeling, and T2 reductions in extensor muscles consistent with fibrosis development. Repeated intra-articular MSU/LPS injections in the rat knee joint induced pathology in multiple tissues and may be a useful means to investigate the relationship between urate crystal deposition and the development of degenerative joint disease.

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