scholarly journals S-B-6. Cerebrospinal Fluid Production Rate in Experimentally induced Cerebral Edema in Dogs

1967 ◽  
Vol 9 ◽  
pp. 258-259
Author(s):  
Osamu SATO ◽  
Michiyuki YAGI ◽  
Yoshiyuki AMANO ◽  
Ryuichi TSUGANE
Keyword(s):  
Cerebrospinal Fluid ◽  
Production Rate ◽  
Cerebral Edema ◽  
Fluid Production ◽  
Experimentally Induced

The cerebrospinal fluid production rate is reduced in dementia of the Alzheimer's type

Neurology ◽  
2001 ◽  
Vol 57 (10) ◽  
pp. 1763-1766 ◽  
Author(s):  
G.D. Silverberg ◽  
G. Heit ◽  
S. Huhn ◽  
R.A. Jaffe ◽  
S.D. Chang ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Production Rate ◽  
Fluid Production

Downregulation of cerebrospinal fluid production in patients with chronic hydrocephalus

2002 ◽  
Vol 97 (6) ◽  
pp. 1271-1275 ◽  
Author(s):  
Gerald D. Silverberg ◽  
Stephen Huhn ◽  
Richard A. Jaffe ◽  
Steven D. Chang ◽  
Thomas Saul ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Production Rate ◽  
Ventricular Catheter ◽  
Chronic Hydrocephalus ◽  
Production Rates ◽  
Normal Range ◽  
Content Type ◽  
Fluid Production ◽  
Csf Production ◽  
Fine Print

Object. The goal of this study was to determine the effect of hydrocephalus on cerebrospinal fluid (CSF) production rates in patients with acute and chronic hydrocephalus. Methods. The authors studied CSF production both in patients presenting with acute and chronic hydrocephalus, and patients with Parkinson disease (PD) of a similar mean age, whose CSF production was known to be normal. A modification of the Masserman method was used to measure CSF production through a ventricular catheter. The CSF production rates (means ± standard deviations) in the three groups were then compared. The patients with PD had a mean CSF production rate of 0.42 ± 0.13 ml/minute; this value lies within the normal range measured using this technique. Patients with acute hydrocephalus had a similar CSF production rate of 0.4 ± 0.13 ml/minute, whereas patients with chronic hydrocephalus had a significantly decreased mean CSF production rate of 0.25 ± 0.08 ml/minute. Conclusions. The authors postulate that chronic increased intracranial pressure causes downregulation of CSF production.

Effect of certain drugs on cerebrospinal fluid production in the dog

1964 ◽  
Vol 206 (2) ◽  
pp. 247-250 ◽  
Author(s):  
W. W. Oppelt ◽  
C. S. Patlak ◽  
D. P. Rall
Keyword(s):  
Cerebrospinal Fluid ◽  
Carbonic Anhydrase ◽  
Production Rate ◽  
Cardiac Glycoside ◽  
Intrathecal Administration ◽  
Production Rates ◽  
Ventriculocisternal Perfusion ◽  
Fluid Production ◽  
Significant Change ◽  
Csf Production

Cerebrospinal fluid (CSF) production rates were measured in the dog by ventriculocisternal perfusion with inulin containing buffer. Normal CSF production rate was found to be about 0.05 ml/min which represents a turnover of 0.4%/min. After intravenous administration of the carbonic anhydrase inhibitors, acetazolamide and methazolamide, a 40–50% decrease in CSF production occurred. An increase in plasma pCO2, by allowing the animals to inhale 95% oxygen, 5% CO2, did not result in any significant change in CSF production. Both intravenous and intrathecal administration of varying doses of the cardiac glycoside, ouabain, did not cause any significant change in CSF production rates. It is concluded that CSF production, in part, is controlled by a carbonic anhydrase system.

Effects of irregular cerebrospinal fluid production rate in human brain ventricular system

2012 ◽  
Author(s):  
Edi Azali Hadzri ◽  
Amir Hamzah Shamsudin ◽  
Kahar Osman ◽  
Mohammed Rafiq Abdul Kadir ◽  
Azian Abd Aziz
Keyword(s):  
Cerebrospinal Fluid ◽  
Human Brain ◽  
Production Rate ◽  
Ventricular System ◽  
Fluid Production ◽  
Brain Ventricular System
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