scholarly journals RHYTHMIC TRANSKRANIAL MAGNETIC STIMULATION IN TREATMENT OF PATIENTS WITH DEPRESSION

2019 ◽  
pp. 90-94
Author(s):  
A. I. Tretiakova ◽  
L. L. Chebotariova ◽  
L. M. Sulii ◽  
V. L. Matrenytskiy
Keyword(s):  
Dorsolateral Prefrontal Cortex ◽  
Depression Scale ◽  
Low Frequency ◽  
Anxiety And Depression ◽  
Depression Severity ◽  
Hospital Anxiety ◽  
Treatment Of Depression ◽  
Dorsolateral Prefrontal ◽  
The Right ◽  
Assessment Scales

23 patients with clinically proven diagnosis of depression were treated with the help of rTMS. The signs of depression were assessed according to the Hospital Anxiety and Depression Scale (HADS) and Zung Self-Rating Depression Scale. The low-frequency (1 Hz) rTMS was conducted on “Neuro-MS/T” with the intensity of 80% from the threshold of motor response to the TMS of the right dorsolateral prefrontal cortex, number of trains – 60, duration – 23 minutes. After 10 sessions of rTMS, the patients noted the improvement of sleep (15), mood improvement (19), a calmer reaction to stressful situations (14). A reduction of depression severity according to assessment scales was also registered (р < 0,05). The therapeutic rTMS method and the chosen protocol of stimulation proved to be effective in treatment of depression and can be used in medical practice under the control of psychotherapist. 23 patients with clinically proven diagnosis of depression were treated with the help of rTMS. The signs of depression were assessed according to the Hospital Anxiety and Depression Scale (HADS) and Zung Self-Rating Depression Scale. The low-frequency (1 Hz) rTMS was conducted on “Neuro-MS/T” with the intensity of 80% from the threshold of motor response to the TMS of the right dorsolateral prefrontal cortex, number of trains – 60, duration – 23 minutes. After 10 sessions of rTMS, the patients noted the improvement of sleep (15), mood improvement (19), a calmer reaction to stressful situations (14). A reduction of depression severity according to assessment scales was also registered (р < 0,05). The therapeutic rTMS method and the chosen protocol of stimulation proved to be effective in treatment of depression and can be used in medical practice under the control of psychotherapist. 23 patients with clinically proven diagnosis of depression were treated with the help of rTMS. The signs of depression were assessed according to the Hospital Anxiety and Depression Scale (HADS) and Zung Self-Rating Depression Scale. The low-frequency (1 Hz) rTMS was conducted on “Neuro-MS/T” with the intensity of 80% from the threshold of motor response to the TMS of the right dorsolateral prefrontal cortex, number of trains – 60, duration – 23 minutes. After 10 sessions of rTMS, the patients noted the improvement of sleep (15), mood improvement (19), a calmer reaction to stressful situations (14). A reduction of depression severity according to assessment scales was also registered (р < 0,05). The therapeutic rTMS method and the chosen protocol of stimulation proved to be effective in treatment of depression and can be used in medical practice under the control of psychotherapist. 23 patients with clinically proven diagnosis of depression were treated with the help of rTMS. The signs of depression were assessed according to the Hospital Anxiety and Depression Scale (HADS) and Zung Self-Rating Depression Scale. The low-frequency (1 Hz) rTMS was conducted on “Neuro-MS/T” with the intensity of 80% from the threshold of motor response to the TMS of the right dorsolateral prefrontal cortex, number of trains – 60, duration – 23 minutes. After 10 sessions of rTMS, the patients noted the improvement of sleep (15), mood improvement (19), a calmer reaction to stressful situations (14). A reduction of depression severity according to assessment scales was also registered (р < 0,05). The therapeutic rTMS method and the chosen protocol of stimulation proved to be effective in treatment of depression and can be used in medical practice under the control of psychotherapist. 23 patients with clinically proven diagnosis of depression were treated with the help of rTMS. The signs of depression were assessed according to the Hospital Anxiety and Depression Scale (HADS) and Zung Self-Rating Depression Scale. The low-frequency (1 Hz) rTMS was conducted on “Neuro-MS/T” with the intensity of 80% from the threshold of motor response to the TMS of the right dorsolateral prefrontal cortex, number of trains – 60, duration – 23 minutes. After 10 sessions of rTMS, the patients noted the improvement of sleep (15), mood improvement (19), a calmer reaction to stressful situations (14). A reduction of depression severity according to assessment scales was also registered (р < 0,05). The therapeutic rTMS method and the chosen protocol of stimulation proved to be effective in treatment of depression and can be used in medical practice under the control of psychotherapist.

scholarly journals RHYTHMIC TRANSKRANIAL MAGNETIC STIMULATION IN TREATMENT OF PATIENTS WITH DEPRESSION

2019 ◽  
pp. 90-94
Author(s):  
A. I. Tretiakova ◽  
L. L. Chebotariova ◽  
L. M. Sulii ◽  
V. L. Matrenytskiy
Keyword(s):  
Dorsolateral Prefrontal Cortex ◽  
Depression Scale ◽  
Low Frequency ◽  
Anxiety And Depression ◽  
Depression Severity ◽  
Hospital Anxiety ◽  
Treatment Of Depression ◽  
Dorsolateral Prefrontal ◽  
The Right ◽  
Assessment Scales

23 patients with clinically proven diagnosis of depression were treated with the help of rTMS. The signs of depression were assessed according to the Hospital Anxiety and Depression Scale (HADS) and Zung Self-Rating Depression Scale. The low-frequency (1 Hz) rTMS was conducted on “Neuro-MS/T” with the intensity of 80% from the threshold of motor response to the TMS of the right dorsolateral prefrontal cortex, number of trains – 60, duration – 23 minutes. After 10 sessions of rTMS, the patients noted the improvement of sleep (15), mood improvement (19), a calmer reaction to stressful situations (14). A reduction of depression severity according to assessment scales was also registered (р < 0,05). The therapeutic rTMS method and the chosen protocol of stimulation proved to be effective in treatment of depression and can be used in medical practice under the control of psychotherapist. 23 patients with clinically proven diagnosis of depression were treated with the help of rTMS. The signs of depression were assessed according to the Hospital Anxiety and Depression Scale (HADS) and Zung Self-Rating Depression Scale. The low-frequency (1 Hz) rTMS was conducted on “Neuro-MS/T” with the intensity of 80% from the threshold of motor response to the TMS of the right dorsolateral prefrontal cortex, number of trains – 60, duration – 23 minutes. After 10 sessions of rTMS, the patients noted the improvement of sleep (15), mood improvement (19), a calmer reaction to stressful situations (14). A reduction of depression severity according to assessment scales was also registered (р < 0,05). The therapeutic rTMS method and the chosen protocol of stimulation proved to be effective in treatment of depression and can be used in medical practice under the control of psychotherapist. 23 patients with clinically proven diagnosis of depression were treated with the help of rTMS. The signs of depression were assessed according to the Hospital Anxiety and Depression Scale (HADS) and Zung Self-Rating Depression Scale. The low-frequency (1 Hz) rTMS was conducted on “Neuro-MS/T” with the intensity of 80% from the threshold of motor response to the TMS of the right dorsolateral prefrontal cortex, number of trains – 60, duration – 23 minutes. After 10 sessions of rTMS, the patients noted the improvement of sleep (15), mood improvement (19), a calmer reaction to stressful situations (14). A reduction of depression severity according to assessment scales was also registered (р < 0,05). The therapeutic rTMS method and the chosen protocol of stimulation proved to be effective in treatment of depression and can be used in medical practice under the control of psychotherapist. 23 patients with clinically proven diagnosis of depression were treated with the help of rTMS. The signs of depression were assessed according to the Hospital Anxiety and Depression Scale (HADS) and Zung Self-Rating Depression Scale. The low-frequency (1 Hz) rTMS was conducted on “Neuro-MS/T” with the intensity of 80% from the threshold of motor response to the TMS of the right dorsolateral prefrontal cortex, number of trains – 60, duration – 23 minutes. After 10 sessions of rTMS, the patients noted the improvement of sleep (15), mood improvement (19), a calmer reaction to stressful situations (14). A reduction of depression severity according to assessment scales was also registered (р < 0,05). The therapeutic rTMS method and the chosen protocol of stimulation proved to be effective in treatment of depression and can be used in medical practice under the control of psychotherapist. 23 patients with clinically proven diagnosis of depression were treated with the help of rTMS. The signs of depression were assessed according to the Hospital Anxiety and Depression Scale (HADS) and Zung Self-Rating Depression Scale. The low-frequency (1 Hz) rTMS was conducted on “Neuro-MS/T” with the intensity of 80% from the threshold of motor response to the TMS of the right dorsolateral prefrontal cortex, number of trains – 60, duration – 23 minutes. After 10 sessions of rTMS, the patients noted the improvement of sleep (15), mood improvement (19), a calmer reaction to stressful situations (14). A reduction of depression severity according to assessment scales was also registered (р < 0,05). The therapeutic rTMS method and the chosen protocol of stimulation proved to be effective in treatment of depression and can be used in medical practice under the control of psychotherapist.

scholarly journals Self-compassion and dorsolateral prefrontal cortex activity during sad self-face recognition in depressed adolescents

2020 ◽  
pp. 1-10
Author(s):  
Guanmin Liu ◽  
Na Zhang ◽  
Jia Yuan Teoh ◽  
Christine Egan ◽  
Thomas A. Zeffiro ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Face Recognition ◽  
Dorsolateral Prefrontal Cortex ◽  
Adolescent Depression ◽  
Cingulate Cortex ◽  
Anterior Cingulate ◽  
Depression Severity ◽  
Self Compassion ◽  
Dorsolateral Prefrontal ◽  
The Right

Abstract Background Given the prevalence of adolescent depression and the modest effects of current treatments, research ought to inform development of effective intervention strategies. Self-compassion is inversely associated with depression, and self-compassion interventions have demonstrated promising effects on reducing depression. However, little is known about the neural mechanisms underlying that relationship. Maladaptive self-processing is a characteristic of depression that contributes to the onset and chronicity of depression. Because our own face is an automatic and direct cue for self-processing, this study investigated whether self-compassion was associated with neural responses during sad v. neutral self-face recognition and explore their relationship with depression severity in depressed adolescents and healthy controls (HCs). Methods During functional magnetic resonance imaging, 81 depressed youth and 37 HCs were instructed to identify whether morphed self or other faces with sad, happy, or neutral expressions resembled their own. Results Self-compassion correlated negatively with activity during sad v. neutral self-face recognition in the dorsal anterior cingulate cortex in the total sample, and in the right posterior cingulate cortex/precuneus in HCs, respectively. In depressed adolescents, higher self-compassion correlated with lower activity during sad v. neutral self-face recognition in the right dorsolateral prefrontal cortex (DLPFC), implying that less cognitive effort might be needed to avoid dwelling on sad self-faces and/or regulate negative affect induced by them. Moreover, higher self-compassion mediated the relationship between lower DLPFC activity and reduced depression severity. Conclusions Our findings imply that DLPFC activity might be a biological marker of a successful self-compassion intervention as potential treatment for adolescent depression.

scholarly journals Association of Lesion Location and Depressive Symptoms Poststroke

Stroke ◽  
2021 ◽  
Author(s):  
Julian Klingbeil ◽  
Max-Lennart Brandt ◽  
Max Wawrzyniak ◽  
Anika Stockert ◽  
Hans R. Schneider ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Depressive Symptoms ◽  
Right Hemisphere ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Stroke Severity ◽  
Poststroke Depression ◽  
Hospital Anxiety ◽  
Ventrolateral Prefrontal Cortex ◽  
The Right

Background and Purpose: Poststroke depression is a common stroke sequel, yet its neurobiological substrates are still unclear. We sought to determine whether specific lesion locations are associated with depressive symptoms after stroke. Methods: In a prospective study, 270 patients with first ever stroke were repeatedly tested with the depression subscale of the Hospital Anxiety and Depression Scale within the first 4 weeks and 6 months after stroke. Voxel-based lesion behavior mapping based on clinical imaging was performed to test for associations between symptoms of depression and lesion locations. Results: Frequency of poststroke depression (Hospital Anxiety and Depression Scale-D score >7) after 6 months was 19.6%. Higher Hospital Anxiety and Depression Scale-D scores for depression within the first 4 weeks were the only independent predictor for poststroke depression after 6 months in a multiple logistic regression also including age, sex, lesion volume, stroke severity, Barthel-Index, and the anxiety subscale of the Hospital Anxiety and Depression Scale. Nonparametric permutation-test based voxel-based lesion behavior mapping identified a cluster of voxels mostly within the left ventrolateral prefrontal cortex where lesions were significantly associated with more depressive symptoms after 6 months. No such association was observed within the right hemisphere despite better lesion coverage. Conclusions: Lesions in the left ventrolateral prefrontal cortex increase the risk of depressive symptoms 6 months poststroke. Lesions within the right hemisphere are unrelated to depressive symptoms. Recognition of left frontal lesions as a risk factor should help in the early diagnosis of poststroke depression through better risk stratification. The results are in line with evidence from functional imaging and noninvasive brain stimulation in patients without focal brain damage indicating that dysfunction in the left lateral prefrontal cortex contributes to depressive disorders.

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