scholarly journals Association of Lesion Location and Depressive Symptoms Poststroke

Stroke ◽  
2021 ◽  
Author(s):  
Julian Klingbeil ◽  
Max-Lennart Brandt ◽  
Max Wawrzyniak ◽  
Anika Stockert ◽  
Hans R. Schneider ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Depressive Symptoms ◽  
Right Hemisphere ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Stroke Severity ◽  
Poststroke Depression ◽  
Hospital Anxiety ◽  
Ventrolateral Prefrontal Cortex ◽  
The Right

Background and Purpose: Poststroke depression is a common stroke sequel, yet its neurobiological substrates are still unclear. We sought to determine whether specific lesion locations are associated with depressive symptoms after stroke. Methods: In a prospective study, 270 patients with first ever stroke were repeatedly tested with the depression subscale of the Hospital Anxiety and Depression Scale within the first 4 weeks and 6 months after stroke. Voxel-based lesion behavior mapping based on clinical imaging was performed to test for associations between symptoms of depression and lesion locations. Results: Frequency of poststroke depression (Hospital Anxiety and Depression Scale-D score >7) after 6 months was 19.6%. Higher Hospital Anxiety and Depression Scale-D scores for depression within the first 4 weeks were the only independent predictor for poststroke depression after 6 months in a multiple logistic regression also including age, sex, lesion volume, stroke severity, Barthel-Index, and the anxiety subscale of the Hospital Anxiety and Depression Scale. Nonparametric permutation-test based voxel-based lesion behavior mapping identified a cluster of voxels mostly within the left ventrolateral prefrontal cortex where lesions were significantly associated with more depressive symptoms after 6 months. No such association was observed within the right hemisphere despite better lesion coverage. Conclusions: Lesions in the left ventrolateral prefrontal cortex increase the risk of depressive symptoms 6 months poststroke. Lesions within the right hemisphere are unrelated to depressive symptoms. Recognition of left frontal lesions as a risk factor should help in the early diagnosis of poststroke depression through better risk stratification. The results are in line with evidence from functional imaging and noninvasive brain stimulation in patients without focal brain damage indicating that dysfunction in the left lateral prefrontal cortex contributes to depressive disorders.

A-121 Functional Outcomes in Bilingual Persons with Traumatic Brain: The Role of Mood

2021 ◽  
Vol 36 (6) ◽  
pp. 1171-1171
Author(s):  
Winter Olmos ◽  
Daniel W Lopez-Hernandez ◽  
Isabel Munoz ◽  
Laura Schierholz ◽  
Rachel A Rugh-Fraser ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Functional Outcomes ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Depression And Anxiety ◽  
Hospital Anxiety ◽  
Anxiety Levels ◽  
The Relationship ◽  
Pearson Correlations

Abstract Introduction We examined the relationship between depression and anxiety, language, and functional outcomes in persons with traumatic brain injury (TBI). Methods The sample consisted of 48 acute TBI (ATBI: 23 Spanish-English Bilinguals; 25 English monolinguals), 30 chronic TBI (CTBI: 17 Spanish English Bilinguals; 12 English monolinguals), and 47 healthy comparison (HC: 29 Spanish-English Bilinguals; 18 English monolinguals) participants. The Hospital Anxiety and Depression Scale was used to measure depression (HADS-D) and anxiety (HADS-A). The Mayo Portland Adaptability Inventory-4 (MPAI-4) was used to measure functional outcomes (ability, adjustment, participation). Results An ANCOVA, controlling for age, revealed the ATBI group reported lower anxiety levels compared to the CTBI group, p = 0.034 np2 = 0.06. HC participants demonstrated significantly higher functional ability compared to both TBI groups, p < 0.05, np2 = 0.08–0.19. The ATBI group demonstrated worse participation scores compared to the CTBI and HC groups, p = 0.001, np2 = 0.11. Pearson correlations revealed mood was related to functional status in ATBI monolinguals (HADS-A: r = 0.29–0.64; HADS-D, r = 0.49–0.62). Monolingual participants with ATBI demonstrated correlations between depressive symptoms and functional adjustment (r = 0.57, p = 0.005) and ability (r = 0.44, p = 0.034). For monolinguals with CTBI, HADS-A correlated with functional outcomes, r = 0.60–0.66, p < 0.05. For bilinguals with CTBI, functional outcomes correlated with HADS-A, r = 0.53–0.66, p < 0.05, and HADS-D, r = 0.54–0.66, p < 0.05. For HC monolinguals, functional outcomes correlated with HADS-A, r = 0.53–0.70, p < 0.05, and HADS-D, r = 0.50–0.72, p < 0.05. Finally, for HC bilinguals, functional outcomes correlated with HADS-A, r = 0.59–0.68, p < 0.05. Conclusion Our results suggest that a relationship between anxiety and depressive symptoms is related more to functional outcomes in monolingual TBI survivors compared to bilingual TBI survivors.

scholarly journals Influence of socio-economic deprivation on the prevalence and outcome of depression in primary care

2001 ◽  
Vol 178 (1) ◽  
pp. 12-17 ◽  
Author(s):  
K. Ostler ◽  
C. Thompson ◽  
A.-L. K. Kinmonth ◽  
R. C. Peveler ◽  
L. Stevens ◽  
...  
Keyword(s):  
Primary Care ◽  
General Practice ◽  
Depressive Symptoms ◽  
Health Inequalities ◽  
Employment Status ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Hospital Anxiety ◽  
Powerful Predictor ◽  
Economic Deprivation

BackgroundHealth inequalities exist for many disorders, but the contribution of deprivation to the prevalence and outcome of depressive symptoms in primary care populations has been infrequently studied.AimsTo examine the influence of Jarman under-privileged area (UPA) scores on the prevalence and outcome of depressive symptoms in general practice patients.Method18 414 patients attending 55 representative practices completed the Hospital Anxiety and Depression Scale and a questionnaire for employment status. Outcome of those screening positive was assessed at 6 weeks and 6 months.ResultsThe UPA score accounted for 48.3% of the variance between practices in prevalence of depressive symptoms. Attending a high UPA score practice predicted persistence of depressive symptoms to 6 months.ConclusionsThe socio-economic deprivation of a practice locality is a powerful predictor of the prevalence and persistence of depressive symptoms.

scholarly journals RHYTHMIC TRANSKRANIAL MAGNETIC STIMULATION IN TREATMENT OF PATIENTS WITH DEPRESSION

2019 ◽  
pp. 90-94
Author(s):  
A. I. Tretiakova ◽  
L. L. Chebotariova ◽  
L. M. Sulii ◽  
V. L. Matrenytskiy
Keyword(s):  
Dorsolateral Prefrontal Cortex ◽  
Depression Scale ◽  
Low Frequency ◽  
Anxiety And Depression ◽  
Depression Severity ◽  
Hospital Anxiety ◽  
Treatment Of Depression ◽  
Dorsolateral Prefrontal ◽  
The Right ◽  
Assessment Scales

23 patients with clinically proven diagnosis of depression were treated with the help of rTMS. The signs of depression were assessed according to the Hospital Anxiety and Depression Scale (HADS) and Zung Self-Rating Depression Scale. The low-frequency (1 Hz) rTMS was conducted on “Neuro-MS/T” with the intensity of 80% from the threshold of motor response to the TMS of the right dorsolateral prefrontal cortex, number of trains – 60, duration – 23 minutes. After 10 sessions of rTMS, the patients noted the improvement of sleep (15), mood improvement (19), a calmer reaction to stressful situations (14). A reduction of depression severity according to assessment scales was also registered (р < 0,05). The therapeutic rTMS method and the chosen protocol of stimulation proved to be effective in treatment of depression and can be used in medical practice under the control of psychotherapist. 23 patients with clinically proven diagnosis of depression were treated with the help of rTMS. The signs of depression were assessed according to the Hospital Anxiety and Depression Scale (HADS) and Zung Self-Rating Depression Scale. The low-frequency (1 Hz) rTMS was conducted on “Neuro-MS/T” with the intensity of 80% from the threshold of motor response to the TMS of the right dorsolateral prefrontal cortex, number of trains – 60, duration – 23 minutes. After 10 sessions of rTMS, the patients noted the improvement of sleep (15), mood improvement (19), a calmer reaction to stressful situations (14). A reduction of depression severity according to assessment scales was also registered (р < 0,05). The therapeutic rTMS method and the chosen protocol of stimulation proved to be effective in treatment of depression and can be used in medical practice under the control of psychotherapist. 23 patients with clinically proven diagnosis of depression were treated with the help of rTMS. The signs of depression were assessed according to the Hospital Anxiety and Depression Scale (HADS) and Zung Self-Rating Depression Scale. The low-frequency (1 Hz) rTMS was conducted on “Neuro-MS/T” with the intensity of 80% from the threshold of motor response to the TMS of the right dorsolateral prefrontal cortex, number of trains – 60, duration – 23 minutes. After 10 sessions of rTMS, the patients noted the improvement of sleep (15), mood improvement (19), a calmer reaction to stressful situations (14). A reduction of depression severity according to assessment scales was also registered (р < 0,05). The therapeutic rTMS method and the chosen protocol of stimulation proved to be effective in treatment of depression and can be used in medical practice under the control of psychotherapist. 23 patients with clinically proven diagnosis of depression were treated with the help of rTMS. The signs of depression were assessed according to the Hospital Anxiety and Depression Scale (HADS) and Zung Self-Rating Depression Scale. The low-frequency (1 Hz) rTMS was conducted on “Neuro-MS/T” with the intensity of 80% from the threshold of motor response to the TMS of the right dorsolateral prefrontal cortex, number of trains – 60, duration – 23 minutes. After 10 sessions of rTMS, the patients noted the improvement of sleep (15), mood improvement (19), a calmer reaction to stressful situations (14). A reduction of depression severity according to assessment scales was also registered (р < 0,05). The therapeutic rTMS method and the chosen protocol of stimulation proved to be effective in treatment of depression and can be used in medical practice under the control of psychotherapist. 23 patients with clinically proven diagnosis of depression were treated with the help of rTMS. The signs of depression were assessed according to the Hospital Anxiety and Depression Scale (HADS) and Zung Self-Rating Depression Scale. The low-frequency (1 Hz) rTMS was conducted on “Neuro-MS/T” with the intensity of 80% from the threshold of motor response to the TMS of the right dorsolateral prefrontal cortex, number of trains – 60, duration – 23 minutes. After 10 sessions of rTMS, the patients noted the improvement of sleep (15), mood improvement (19), a calmer reaction to stressful situations (14). A reduction of depression severity according to assessment scales was also registered (р < 0,05). The therapeutic rTMS method and the chosen protocol of stimulation proved to be effective in treatment of depression and can be used in medical practice under the control of psychotherapist.

scholarly journals Comparing the Performance of the HADS and the GDS-15 in the AIBL Study

2015 ◽  
Vol 27 (9) ◽  
pp. 1577-1578 ◽  
Author(s):  
Guy Campbell ◽  
Christina Bryant ◽  
Kathryn A. Ellis ◽  
Rachel Buckley ◽  
David Ames ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Depressive Symptoms ◽  
Geriatric Depression Scale ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Hospital Inpatient ◽  
Geriatric Depression ◽  
Hospital Anxiety ◽  
Depression Subscale ◽  
Inpatient Settings

Screening measures such as the 15-item Geriatric Depression Scale (GDS-15) (Sheikh and Yesavage, 1986) and the Hospital Anxiety and Depression Scale (HADS) (Zigmond and Snaith, 1983) are important tools in the recognition of depressive symptoms in older people. While these measures are widely used, there is evidence of specific weaknesses in some cohorts and contexts, with the GDS-15 showing limitations in the context of cognitive impairment (Gilley and Wilson, 1997), and the depression subscale of the HADS (HADS-D) losing sensitivity in the context of older participants in hospital inpatient settings (Davies et al., 1993).

scholarly journals Exploring the factors associated with coronaphobia among physicians during the COVID-19 outbreak in Egypt

2021 ◽  
Vol 57 (1) ◽  
Author(s):  
Mohamed Abdelghani ◽  
Mervat S. Hassan ◽  
Hayam M. Elgohary ◽  
Eman Fouad
Keyword(s):  
Depressive Symptoms ◽  
Virus Infection ◽  
Depression Scale ◽  
Cross Sectional Study ◽  
Anxiety And Depression ◽  
Hospital Anxiety ◽  
Cross Sectional ◽  
Factors Associated ◽  
Death Wishes ◽  
Assessment Measures

Abstract Background Coronaphobia refers to intensified and persistent fears of contracting COVID-19 virus infection. This study aimed to evaluate the newly termed phenomenon, coronaphobia, and address its associated correlates among Egyptian physicians during the outbreak. A cross-sectional study, including a total of 426 Egyptian physicians working during COVID-19 outbreak, was conducted between March 1st and May 1st, 2020. The Fear of COVID-19 Scale (FCV-19S) and Hospital Anxiety and Depression Scale (HADS) were utilized for assessment of coronaphobia, and comorbid anxiety and depressive symptoms among physicians, respectively during the outbreak. Results Moderate-to-severe symptoms of anxiety and depression were reported by 28% and 30% of physicians, respectively. Physicians experiencing higher levels of coronaphobia were more likely to be females, nonsmokers, having death wishes and/or self-harming thoughts, receiving insufficient training, dissatisfied with their personal protective equipment (PPE), and had colleagues infected with COVID-19 virus infection. Coronaphobia was positively correlated with anxiety (r = 0.59, P < 0.001) and depressive symptoms (r = 0.47, P < 0.001). Conclusions Egyptian physicians experienced higher levels of coronaphobia, anxiety, and depressive symptoms during the COVID-19 outbreak. Yet, frontline physicians did not differ from their second-line counterparts regarding the aforementioned symptoms. Routine mental and physical assessment measures of medical staff should be implemented.

scholarly journals Relationship between emotional states before cardiac valve surgeries with postoperative complications

2020 ◽  
Vol 41 ◽  
Author(s):  
Hélen Francine Rodrigues ◽  
Rejane Kiyoma Furuya ◽  
Rosana Aparecida Spadoti Dantas ◽  
Rafaela Dias Coloni Morelato ◽  
Carina Aparecida Marosti Dessotte
Keyword(s):  
Depressive Symptoms ◽  
Postoperative Complications ◽  
Depression Scale ◽  
University Hospital ◽  
Anxiety And Depression ◽  
Depression Symptoms ◽  
Emotional States ◽  
Hospital Anxiety ◽  
Valve Repair ◽  
Probabilistic Sample

ABSTRACT Objective: To investigate associations between preoperative anxiety and depression symptoms and postoperative complications and the sociodemographic and clinical characteristics of patients undergoing valve repair surgery. Method: Observational, exploratory and prospective study. The consecutive non-probabilistic sample consisted of patients undergoing their first valve repair surgery. Data were collected from September 2013 to September 2015, in a university hospital in the interior of São Paulo, Brazil. Symptoms were assessed using the Hospital Anxiety and Depression Scale and analyzed using Mann-Whitney and Spearman correlation; alpha was established at 5%. Results: Among the 70 participants, depressive symptoms were more frequent among women (p=0.042) and among patients experiencing postoperative agitation (p=0.039) Conclusion: In this study, depressive symptoms were associated with being a woman and postoperative agitation; the same was not true in regard to anxiety symptoms.

scholarly journals RHYTHMIC TRANSKRANIAL MAGNETIC STIMULATION IN TREATMENT OF PATIENTS WITH DEPRESSION

2019 ◽  
pp. 90-94
Author(s):  
A. I. Tretiakova ◽  
L. L. Chebotariova ◽  
L. M. Sulii ◽  
V. L. Matrenytskiy
Keyword(s):  
Dorsolateral Prefrontal Cortex ◽  
Depression Scale ◽  
Low Frequency ◽  
Anxiety And Depression ◽  
Depression Severity ◽  
Hospital Anxiety ◽  
Treatment Of Depression ◽  
Dorsolateral Prefrontal ◽  
The Right ◽  
Assessment Scales

23 patients with clinically proven diagnosis of depression were treated with the help of rTMS. The signs of depression were assessed according to the Hospital Anxiety and Depression Scale (HADS) and Zung Self-Rating Depression Scale. The low-frequency (1 Hz) rTMS was conducted on “Neuro-MS/T” with the intensity of 80% from the threshold of motor response to the TMS of the right dorsolateral prefrontal cortex, number of trains – 60, duration – 23 minutes. After 10 sessions of rTMS, the patients noted the improvement of sleep (15), mood improvement (19), a calmer reaction to stressful situations (14). A reduction of depression severity according to assessment scales was also registered (р < 0,05). The therapeutic rTMS method and the chosen protocol of stimulation proved to be effective in treatment of depression and can be used in medical practice under the control of psychotherapist. 23 patients with clinically proven diagnosis of depression were treated with the help of rTMS. The signs of depression were assessed according to the Hospital Anxiety and Depression Scale (HADS) and Zung Self-Rating Depression Scale. The low-frequency (1 Hz) rTMS was conducted on “Neuro-MS/T” with the intensity of 80% from the threshold of motor response to the TMS of the right dorsolateral prefrontal cortex, number of trains – 60, duration – 23 minutes. After 10 sessions of rTMS, the patients noted the improvement of sleep (15), mood improvement (19), a calmer reaction to stressful situations (14). A reduction of depression severity according to assessment scales was also registered (р < 0,05). The therapeutic rTMS method and the chosen protocol of stimulation proved to be effective in treatment of depression and can be used in medical practice under the control of psychotherapist. 23 patients with clinically proven diagnosis of depression were treated with the help of rTMS. The signs of depression were assessed according to the Hospital Anxiety and Depression Scale (HADS) and Zung Self-Rating Depression Scale. The low-frequency (1 Hz) rTMS was conducted on “Neuro-MS/T” with the intensity of 80% from the threshold of motor response to the TMS of the right dorsolateral prefrontal cortex, number of trains – 60, duration – 23 minutes. After 10 sessions of rTMS, the patients noted the improvement of sleep (15), mood improvement (19), a calmer reaction to stressful situations (14). A reduction of depression severity according to assessment scales was also registered (р < 0,05). The therapeutic rTMS method and the chosen protocol of stimulation proved to be effective in treatment of depression and can be used in medical practice under the control of psychotherapist. 23 patients with clinically proven diagnosis of depression were treated with the help of rTMS. The signs of depression were assessed according to the Hospital Anxiety and Depression Scale (HADS) and Zung Self-Rating Depression Scale. The low-frequency (1 Hz) rTMS was conducted on “Neuro-MS/T” with the intensity of 80% from the threshold of motor response to the TMS of the right dorsolateral prefrontal cortex, number of trains – 60, duration – 23 minutes. After 10 sessions of rTMS, the patients noted the improvement of sleep (15), mood improvement (19), a calmer reaction to stressful situations (14). A reduction of depression severity according to assessment scales was also registered (р < 0,05). The therapeutic rTMS method and the chosen protocol of stimulation proved to be effective in treatment of depression and can be used in medical practice under the control of psychotherapist. 23 patients with clinically proven diagnosis of depression were treated with the help of rTMS. The signs of depression were assessed according to the Hospital Anxiety and Depression Scale (HADS) and Zung Self-Rating Depression Scale. The low-frequency (1 Hz) rTMS was conducted on “Neuro-MS/T” with the intensity of 80% from the threshold of motor response to the TMS of the right dorsolateral prefrontal cortex, number of trains – 60, duration – 23 minutes. After 10 sessions of rTMS, the patients noted the improvement of sleep (15), mood improvement (19), a calmer reaction to stressful situations (14). A reduction of depression severity according to assessment scales was also registered (р < 0,05). The therapeutic rTMS method and the chosen protocol of stimulation proved to be effective in treatment of depression and can be used in medical practice under the control of psychotherapist.

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