Development of prevention and treatment of sarcopenia by strength training with blood flow restriction

The aim of this study was to evaluate the impact of high-intensity strength training (ST) or low-intensity strength training with blood flow restriction (ST-BFR) on monocyte subsets, the expression of C-C chemokine receptor 5 (CCR5), and CD16 on monocytes, and tumor necrosis factor alpha (TNF-α) production of overweight men. Thirty overweight men were randomly assigned to conventional ST or ST-BFR. Both groups performed exercises of knee extension and biceps curl with equal volume (3 sessions/week) over 8 weeks, and the peripheral frequency of monocytes (CD14+CD16−, classical monocytes; CD14+CD16+, intermediate monocytes; CD14−CD16+, nonclassical monocytes), the mean fluorescence intensity (MFI) of CCR5 and CD16 on CD14+ monocytes; and the production of TNF-α by lipopolysaccharide (LPS)-stimulated cells were quantified. Eight weeks of ST increased the frequency of CD14+CD16− monocytes (p = 0.04) and reduced the percentage of CD14−CD16+ (p = 0.02) and the production of TNF-α by LPS-stimulated cells (p = 0.03). The MFI of CD16 on CD14+ monocytes decreased after the ST intervention (p = 0.02). No difference in monocyte subsets, CCR5 or CD16 expression, and TNF-α production were identified after ST-BFR intervention (p > 0.05). The adoption of ST promotes anti-inflammatory effects on monocyte subsets of overweight men, but this effect was lost when BFR was adopted. Novelty High-intensity strength training reduces the production of TNF-α and the peripheral frequency of CD16+ monocytes in overweight men. Blood flow restriction method blunts the strength training adaptations on monocyte subsets and pro-inflammatory TNF-α production in overweight men.

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BLOOD FLOW RESTRICTION IN STRENGTH TRAINING (REVIEW)

European Journal of Physical Education and Sport Science ◽

10.46827/ejpe.v6i11.3629 ◽

2021 ◽

Vol 6 (11) ◽

Author(s):

Ömür Gülfirat ◽

Halil Bişgin

Keyword(s):

Blood Flow ◽

Resistance Training ◽

Strength Training ◽

Venous Blood ◽

General Information ◽

Blood Flow Restriction ◽

Venous Blood Flow ◽

Training Methods ◽

Post Injury ◽

Flow Restriction

Background/Objective: The aim of this review is to investigate general information about blood flow restriction in strength training. Methods: In this study, the related literature was studied by using the screening model. Data were obtained from various articles and internet websites. Of the indexes and databases used in the research; (6) scientific studies on Yöktez, (3) on Pubmed, (3) on Researchgate, (2) on Physiopedia and (4) on Google Scholar were examined. Scientific studies where the effects of blood flow restriction on sedentary individuals (11), the effects of blood flow restriction on individual athletes (1), the effects of blood flow restriction on team athletes (3), and the effects of blood flow restriction on individuals after injury examined (3), were used in our research. Conclusion: The aim of this review is to investigate the application methods and effects of venous blood flow restriction technique, which has recently become popular in resistance training. In this direction, resistance training applied with the BFR technique has been examined with this review by making a literature review. As a result, it is thought that the BFR technique may have a positive effect on the post-injury recovery process and can also help increase the sportive performance and competition gain. It can be said that it can give positive results in terms of hypertrophy if it is evaluated as an aid to strength training, which is quite popular. It is estimated that they will be able to do their daily activities more freely if it is applied to elderly people. It is thought that a very popular movement such as squat, when applied together with venous blood flow restriction, can increase the strength of jumping, besides, if it is applied in anaerobic-based branches, sportive performance can also increase positively. Article visualizations:<img src="/-counters-/edu_01/0777/a.php" alt="Hit counter" />

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