Equine astma: huidige kennis van zaken

Equine astma is de overkoepelende term voor een inflammatoir proces ter hoogte van de diepere luchtwegen. Deze aandoening wordt verder onderverdeeld in lichte tot matige astma, beter bekend als “inflammatory airway disease” (IAD), en ernstige astma, beter bekend als “recurrent airway obstruction” (RAO). RAO veroorzaakt inflammatie en obstructie van de diepe luchtwegen, wat leidt tot chronische hoest, verhoogde ademhalingsinspanning in rust en inspanningsintolerantie, meestal bij paarden ouder dan zeven jaar. IAD daarentegen kan op elke leeftijd voorkomen en de klinische tekenen zijn vaak veel subtieler, namelijk verminderd presteren en occasioneel hoesten. Equine astma wordt voornamelijk getriggerd door een hoge concentratie aan stof en schimmelsporen in de stalomgeving of pollen tijdens de zomermaanden in het geval van “summer pasture associated” RAO (SPARAO). De gouden standaard om equine astma te diagnosticeren is het uitvoeren van een endoscopie, gevolgd door een broncho-alveolaire lavage (BAL). Het aanpassen van de omgeving is en blijft de belangrijkste behandelingsmethode, vaak in combinatie met het tijdelijk toedienen van corticosteroïden en bronchodilatatoren.

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Spi2 gene polymorphism is not associated with recurrent airway obstruction and inflammatory airway disease in thoroughbred horses

Genetics and Molecular Biology ◽

10.1590/s1415-47572011005000017 ◽

2011 ◽

Vol 34 (3) ◽

pp. 456-458

Author(s):

Aline Correa da Silva ◽

Karin Erica Brass ◽

Elgion da Silva Loreto ◽

Myriam Elizabeth Vinocur ◽

Ricardo Pozzobon ◽

...

Keyword(s):

Gene Polymorphism ◽

Airway Obstruction ◽

Airway Disease ◽

Recurrent Airway Obstruction ◽

Thoroughbred Horses ◽

Inflammatory Airway Disease

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Usefulness of the assessment of discharge accumulation in the lower airways and tracheal septum thickening in the differential diagnosis of recurrent airway obstruction (RAO) and inflammatory airway disease (IAD) in the horse

Polish Journal of Veterinary Sciences ◽

10.2478/pjvs-2014-0035 ◽

2014 ◽

Vol 17 (2) ◽

pp. 247-253 ◽

Cited By ~ 7

Author(s):

B. Wysocka ◽

W. Kluciński

Keyword(s):

Differential Diagnosis ◽

Airway Obstruction ◽

Airway Disease ◽

Endoscopic Examination ◽

Recurrent Airway Obstruction ◽

Tracheal Lumen ◽

Endoscopic Evaluation ◽

Inflammatory Airway Disease ◽

Lower Airways ◽

Tracheal Bifurcation

Abstract The aim of the present study was to use endoscopic evaluation to compare the grade of accumulation of discharge in the lower airways of horses with recurrent airway obstruction (RAO) and inflammatory airway disease (IAD), and to estimate the usefulness of endoscopic evaluation in differential diagnosis of these diseases. Endoscopic evaluation consists of: the amount of discharge in the lower part of the trachea and tracheal bifurcation, and the assessment of tracheal septum thickness. This study was performed on 248 horses, 10 were healthy, 97 were diagnosed as RAO, and 141 were diagnosed as IAD. In all animals both a clinical and endoscopic examination were performed. During endoscopy, a score of mucus accumulation was estimated in 3/4 lower of the trachea and in the tracheal bifurcation. In addition to this, thickening of the tracheal septum was also assessed. According to the results of this study, it was estimated that the accumulation of mucus in the lower airways was much more advanced in RAO horses compared to horses with IAD. In horses with RAO there was a marked thickening of the tracheal septum compared to IAD horses. The results indicate the efficacy of scoring the amount of mucus in the tracheal lumen and tracheal bifurcation, as well as the efficacy of the assessment of tracheal septum thickness in the diagnosis of these diseases

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Recurrent Airway Obstruction and Inflammatory Airway Disease

Veterinary Allergy ◽

10.1002/9781118738818.ch55 ◽

2013 ◽

pp. 371-383

Author(s):

Vinzenz Gerber

Keyword(s):

Airway Obstruction ◽

Airway Disease ◽

Recurrent Airway Obstruction ◽

Inflammatory Airway Disease

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Equine asthma: managing the environment

UK-Vet Equine ◽

10.12968/ukve.2019.3.3.78 ◽

2019 ◽

Vol 3 (3) ◽

pp. 78-84 ◽

Cited By ~ 1

Author(s):

Joel William Hotchkiss

Keyword(s):

Environmental Management ◽

Airway Obstruction ◽

Airway Inflammation ◽

Airway Disease ◽

Lower Airway ◽

Recurrent Airway Obstruction ◽

Organic Dust ◽

Inflammatory Airway Disease ◽

Equine Asthma ◽

Environmental Challenge

Equine asthma is an umbrella term defined by nonseptic lower airway inflammation. Currently there are two broad categories, namely mild to moderate equine asthma (formerly known as inflammatory airway disease) and severe equine asthma (formerly known as recurrent airway obstruction or heaves). Environmental challenge is involved in the aetiopathogenesis of both these subcategories. Much of this challenge, and the part that we can control, is provided by the organic dust associated with the stabling of horses. This article reviews the available evidence relating to the environmental management of equine asthma and tries to relate this to practical options for providing a low-dust environment.

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Recurrent Airway Obstruction and Inflammatory Airway Disease

Robinson's Current Therapy in Equine Medicine ◽

10.1016/b978-1-4557-4555-5.00059-5 ◽

2015 ◽

pp. 257-261 ◽

Cited By ~ 2

Author(s):

M. Eilidh Wilson ◽

N. Edward Robinson

Keyword(s):

Airway Obstruction ◽

Airway Disease ◽

Recurrent Airway Obstruction ◽

Inflammatory Airway Disease

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Letter To The Editor

PEDIATRICS ◽

10.1542/peds.98.4.800b ◽

1996 ◽

Vol 98 (4) ◽

pp. 800-801

Author(s):

Clifton T. Furukawa

Keyword(s):

Airway Obstruction ◽

Airway Disease ◽

Airway Responsiveness ◽

Infectious Bronchitis ◽

Airway Diseases ◽

Letter To The Editor ◽

Inflammatory Airway Disease

Asthma is "inflammatory airway disease." However, additional characteristics are necessary to distinguish asthma from other inflammatory airway diseases, such as infectious bronchitis and pneumonia (infectious and toxic). These additional characteristics are at least partial reversibility of airway obstruction and increased airway responsiveness to a variety of stimuli. Thus, "infectious bronchitis" and "allergic bronchitis" are specific for those children who do not have reversible obstruction and hyperresponsiveness to other factors that can trigger obstruction. Wheezing is not necessarily a symptom shared in common among these airway diseases.

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