scholarly journals Involvement of "Thermal Interference" in the Multiple Working Strokes Per Hydrolyzed ATP Observed in Muscle Contraction.

1993 ◽  
Vol 69 (8) ◽  
pp. 227-232
Author(s):  
Kenichiro MOGI
Author(s):  
H. Mohri

In 1959, Afzelius observed the presence of two rows of arms projecting from each outer doublet microtubule of the so-called 9 + 2 pattern of cilia and flagella, and suggested a possibility that the outer doublet microtubules slide with respect to each other with the aid of these arms during ciliary and flagellar movement. The identification of the arms as an ATPase, dynein, by Gibbons (1963)strengthened this hypothesis, since the ATPase-bearing heads of myosin molecules projecting from the thick filaments pull the thin filaments by cross-bridge formation during muscle contraction. The first experimental evidence for the sliding mechanism in cilia and flagella was obtained by examining the tip patterns of molluscan gill cilia by Satir (1965) who observed constant length of the microtubules during ciliary bending. Further evidence for the sliding-tubule mechanism was given by Summers and Gibbons (1971), using trypsin-treated axonemal fragments of sea urchin spermatozoa. Upon the addition of ATP, the outer doublets telescoped out from these fragments and the total length reached up to seven or more times that of the original fragment. Thus, the arms on a certain doublet microtubule can walk along the adjacent doublet when the doublet microtubules are disconnected by digestion of the interdoublet links which connect them with each other, or the radial spokes which connect them with the central pair-central sheath complex as illustrated in Fig. 1. On the basis of these pioneer works, the sliding-tubule mechanism has been established as one of the basic mechanisms for ciliary and flagellar movement.


Author(s):  
S. V. Korobkov ◽  
A. I. Gnyrya ◽  
V. I. Terekhov

The paper considers the dynamic and thermal interference effects on two neighbouring building models in the form of square prisms arranged at a short distance from each other. It is shown how relative positions of the models affect the specific phenomena caused by the airflow interactions.The aim of this paper is to experimentally study the dynamic and thermal interference of a tandem of two building models in the form of square prisms depending on their relative position.The phenomenon of wind loads on buildings and structures has always attracted great interest among engineers and researchers. With the accumulation of knowledge and technical capabilities, the potential for likely ways to study wind flows and their impact on different objects increased. In recent years, the world science has accumulated an extensive knowledge base on wind impacts on objects of various shapes, such as prisms, pyramids, cylinders, etc. Studies are carried out for their mutual impact of several objects on changes in both the wind load and heat exchange. Their mutual effect on the air motion and turbulence is considered.There are two main areas in the field of the wind impact. The first impact is the force load on building, the second is the wind as a source of convective heat exchange. The object of this study is the interference parameters allowing to assess the influence on the field of pressure and heat recoil of disturbances evoked in front of the barriers.At the first stage, physical models help to study the pressure field on different facets and ratios of the local and medium heat exchange under the forced convection conditions. The next step is to jointly consider the wind (dynamic) load and heat flows, attempting to detect the total contribution to changes depending on the reciprocal model arrangement. All experiments are performed in the aerodynamic tube, at the TSUAB department. It is shown that the dynamic and thermal interference ratios vary greatly in two building models. At the same time, the thermal interference is very conservative compared to the dynamic. Using the interference parameters, it is easy to analyze the extreme pressure and the heat flow on the model surface depending on a large number of factors, including their arrangement.


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