scholarly journals Effect of Stimulus Rate and Gender on Auditory Brainstem Response in Korean Young Adults

2015 ◽  
Vol 11 (2) ◽  
pp. 140-155 ◽  
Author(s):  
Chul-Hee Choi ◽  
Ki-Hyeon Jang ◽  
Seong Hee Choi
1983 ◽  
Vol 92 (2) ◽  
pp. 119-123 ◽  
Author(s):  
Irvin J. Gerling ◽  
Terese Finitzo-Hieber

Normative data were collected on 48 subjects to determine the effects of increasing stimulus rates on the auditory brainstem response. These subjects were then compared to 221 patients referred for otoneurologic evaluation. The 90 patients with impaired auditory sensitivity demonstrated significantly less wave V latency shift than either the 131 patients with normal auditory sensitivity or the normal subjects. The incidence of abnormal wave V latency shift was 12% in the patients with normal auditory sensitivity and 8% in the patients with impaired auditory sensitivity. The high stimulus rate was often the only abr parameter indicative of brainstem involvement in patients with documented CNS pathology. The authors conclude that a high stimulus rate contributes to the diagnosis of brainstem pathology often enough to warrant its routine use.


2020 ◽  
Vol 29 (4) ◽  
pp. 873-886
Author(s):  
Adriana De Necker ◽  
Leigh Biagio-de Jager ◽  
Anton Carel Stoltz

Purpose The study investigated whether the auditory brainstem response (ABR) at a baseline and at higher repetition rates can detect if neurodegeneration has occurred in adults living with HIV who present with normal behavioral pure-tone thresholds. Method An exploratory research design was used. Forty adults with HIV (80 ears, 57.5% female; M age = 26.3 years, SD = 3.68) and 20 adults without HIV participated. Phase 1 compared ABR absolute and interwave latencies at a baseline rate. Phase 2 examined the effect of HIV status and category of immunodeficiency on ABR absolute Wave V latency and Wave V latency shift at increased stimulus rates. Analysis included a two-way analysis of variance of the interaction between stimulus rate and HIV status and between CD4+ category and rate, and multiple regression analysis. Results In adults living with HIV, the baseline ABR yielded prolonged Wave III and V absolute latencies and interpeak prolongations in 22.5%. Interaural Wave V latency differences were present in 15% of participants. An additional 15% of ears presented with abnormal Wave V at increased rates. No significant interaction between HIV status and rate in either ear or between CD4+ category and rate was found in either ear ( p > .05). Although rate and gender contributed significantly to the prediction of Wave V latency of the rate study (left and right, p < .001), HIV status did not (left and right, p > .05). Conclusions Although the interaction of HIV status and CD4+ with rate was not significant, more ears were identified with abnormal results at increased stimulus rates than with the baseline ABR alone. The ABR at increased rates may therefore be a valuable addition for the identification of individuals living with HIV with auditory neural deficiencies.


2013 ◽  
Vol 16 (4) ◽  
pp. 221-226 ◽  
Author(s):  
Ahmad Aidil Arafat bin Dzulkarnain ◽  
Umi Sarah Abdul Hadi ◽  
Nur ’Azzah Zakaria

1983 ◽  
Vol 92 (1) ◽  
pp. 59-64 ◽  
Author(s):  
Steven D. Schaefer ◽  
Irvin J. Gerling ◽  
Terese Finitzo-Hieber ◽  
Frances J. Freeman

Twelve spasmodic dysphonia patients were evaluated by three different auditory brainstem response parameters; 75 % were abnormal. Three of the 12 had prolonged wave I-V interpeak latency. Seven had pathologic wave V latency shifts at a high stimulus rate. Amplitude ratios were normal for all subjects. The authors hypothesize that spasmodic dysphonia is a disorder of variable cranial nerve symptom presentations, and offer several possible models to account for its sporadic representation in the nervous system.


2021 ◽  
pp. 019459982110471
Author(s):  
Christopher E. Niemczak ◽  
Travis White-Schwoch ◽  
Abigail Fellows ◽  
Albert Magohe ◽  
Jiang Gui ◽  
...  

Objective Little is known about peripheral auditory function in young adults with HIV, who might be expected to show early evidence of hearing loss if HIV infection or treatment does affect peripheral function. The goal of this study was to compare peripheral auditory function in 2 age- and gender-matched groups of young adults with clinically normal hearing with and without HIV. Study Design Matched cohort study with repeated measures. Setting Infectious disease center in Dar es Salaam, Tanzania. Methods Participants included HIV-positive (n = 38) and HIV-negative (n = 38) adults aged 20 to 30 years who had clinically normal hearing, defined as type A tympanograms, air conduction thresholds ≤25 dB HL bilaterally from 0.5 to 8 kHz, and distortion product otoacoustic emissions (DPOAEs) >6 dB above the noise floor bilaterally from 1.5 to 8 kHz. Participants were tested multiple times over 6-month intervals (average, 2.7 sessions/participant) for a total of 208 observations. Primary outcome measures included tympanograms, air conduction audiograms, DPOAEs, and click-evoked auditory brainstem responses. Results HIV groups did not significantly differ in age, static immittance, or air conduction thresholds. HIV-positive status was independently associated with approximately 3.7-dB lower DPOAE amplitudes from 2 to 8 kHz (95% CI, 1.01-6.82) in both ears and 0.04-µV lower (95% CI, 0.003-0.076) auditory brainstem response wave I amplitudes in the right ear. Conclusion Young adults living with HIV have slightly but reliably smaller DPOAEs and auditory brainstem response wave I amplitudes than matched HIV-negative controls. The magnitude of these differences is small, but these results support measuring peripheral auditory function in HIV-positive individuals as they age.


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