scholarly journals Transvertebral magnetic neuromodulation for the treatment of overactive bladder: 6 months follow-up

2020 ◽  
Vol 8 (4) ◽  
pp. 62-71
Author(s):  
G V. Kovalev ◽  
D. D. Shkarupa ◽  
N. D. Kubin ◽  
A. O. Zaitseva ◽  
I. V. Borodulina ◽  
...  

Introduction. The most common type of lower urinary tract dysfunction is an overactive bladder (OAB). Today there is a need to search for new effective methods of treating this disease.Purpose of the study. To evaluate the effectiveness of transvertebral magnetic neuromodulation (TMN) of the lumbar spine in patients with OAB.Materials and methods. 26 patients were enrolled in the clinical study. The treatment course consisted of 15 procedures (3 times a week for 5 weeks). Before and after treatment at 1, 3 and 6 months, complaints were assessed using the ICIQ-SF and OAB-q SF questionnaires. Objective parameters were assessed by urodynamic tests before and 6 months after treatment.Results. We observed a significant improvement in patients subjective clinical status at all points of assessment. Transvertebral magnetic neuromodulation had the greatest influence on such urodynamic parameters as the first sensation, the first desire, strong desire, maximum cystometric capacity. Patterns of phase hyperactivity were absent in 60.8% of patients after treatment and terminal hyperactivity in 41.7% of patients.Conclusions. This small study observed a significant therapeutic effect of TMN in patients with OAB. Further large placebo-controlled trials are needed to develop universal effective protocols for lower urinary tract dysfunction treatment. 

2021 ◽  
Vol 11 (1) ◽  
pp. 27-32
Author(s):  
Aleksandr I. Gorbunov ◽  
Aleksandr N. Murav’ev ◽  
Evgenij G. Sokolovich ◽  
Petr K. Yablonsky

ABSTRACT: Tuberculosis inflammation of vertebral column (spondylitis) can lead to neurogenic lower urinary tract dysfunction. There is lack of available publications for neurogenic lower urinary tract dysfunction in spinal tuberculosis. OBJECTIVE: To evaluate urodynamic disturbances in spinal tuberculosis before and after surgery for spondylitis. MATERIALS AND METHODS: We observed 19 patients with spinal tuberculosis, who had symptoms of micturitions impairment. 14 patients (73,6%) were male and 5 (26,4%) were female, average age was 43,7 7,9 years (2766). Control evaluation was performed after surgery on day 2128. RESULTS: Before surgery we found detrusor overactivity in 11 (57,9%) patients and 2 of those with detrusor overactivity had detrusor-sphincter dyssynergia. Detrusor hypo-/acontractility was diagnosed in 8 (42,1%). After surgery 5 patients (26,3%) exhibited improvement, in one case urodynamic disturbances were resolved. One patient developed detrusor overactivity and incontinence de novo and one patient had worsening neurological status, loss of sensitivity and acontractile bladder. CONCLUSION: Variable lower urinary tract dysfunction can be diagnosed in spinal tuberculosis. Only 26,3% of patients have improvement after surgery. New conditions or worsening of previous neurogenic lower urinary tract dysfunctions can be observed.


2009 ◽  
Vol 15 (9) ◽  
pp. 1118-1122 ◽  
Author(s):  
JN Panicker ◽  
D Nagaraja ◽  
JME Kovoor ◽  
KPS Nair ◽  
DK Subbakrishna

Background Lower urinary tract dysfunction (LUTD) in multiple sclerosis has been well documented. However, its occurrence and outcome in acute disseminated encephalomyelitis (ADEM) has only been variably reported. Objective To evaluate LUTD in ADEM, correlation with other neurological deficits, and outcome. Methods Patients with ADEM having significant LUTD were evaluated. LUTD was evaluated by symptom analysis, ultrasonography, and urodynamics. Storage symptoms were managed using antimuscarinics and significant voiding dysfunction by catheterization. Results Of 61 patients, 20 (33%) had LUTD. Voiding dysfunction was more common and 16 patients were in urinary retention. Cystometry demonstrated detrusor overactivity in four patients and underactivity in four patients. Incontinence was reported more often in patients with frontoparietal white matter changes in MR imaging. LUTD was found to be associated with occurrence of paraparesis or tetraparesis, though did not predict functional outcome at discharge. At 3 months follow up, five patients continued to have LUTD and urgency and hesitancy were commonest symptoms. Conclusion LUTD is common in ADEM, especially in patients with lower limb pyramidal involvement and its causes multifactorial. Presence of LUTD does not influence the functional outcome of patients with ADEM. Recovery may be incomplete and symptoms may persist even after recovery of other neurological deficits.


2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Fatemeh Saffari ◽  
Abolfazl Mahyar ◽  
Amir Kavian ◽  
Banafsheh Arad

Background: Overactive bladder (OAB) is a common cause of voiding dysfunction in children and is classified as lower urinary tract dysfunction (LUTD). In recent studies, obesity and overweight are assumed as risk factors for voiding dysfunction and urinary incontinence in children. Objectives: This study was conducted to evaluate the correlation between overweight and obesity with OAB in children. Methods: This cross-sectional study measured BMI in 56 children aged between 3 and 16 years with OAB (case group) and 56 healthy matched children (control group). Overweight and obesity were compared between the two groups. The study also accessed lower urinary tract symptoms and their association with BMI in the OAB children. The data were analyzed using the SPSS software version 18.0 for windows (SPSS Inc., Chicago, IL). Results: The mean age of the OAB patients was 7.71 ± 2.65 years, and 38 (67.8%) of them were female. Frequency and holding maneuvers were the most prevalent complaints. A history of urinary tract infection was detected in 46 (82.1%) of the OAB patients. There were no significant differences in overweight and obesity between the two groups (P = 0.23). Conclusions: No correlation was observed between overweight and obesity with OAB. The reason may be different socioeconomic conditions or malnutrition in these children. Thus, it is recommended to perform a study with a larger sample size in our community to assess malnutrition in the general children population.


2017 ◽  
Vol 7 (1) ◽  
pp. 125
Author(s):  
Patrícia Lordêlo ◽  
Alcina Teles

A disfunção do trato urinário inferior (DTUI) na infância apresenta alta prevalência, podendo levar a sintomas de urgência miccional, incontinência urinária, infecção do trato urinário, refluxo vesicoureteral, lesão renal, além de impactos psicoemocionais. A hiperatividade vesical (HV) é a forma mais comum de apresentação da DTUI, sendo caracterizada como uma alteração na fase de enchimento vesical, acompanhada por sintomas urinários próprios desta fase, mas com um padrão de fluxo urinário normal e sem apresentação de resíduo pós-miccional. A sua fisiopatologia ainda é controversa, e engloba possibilidades de alterações de origem central, de desencadeamento de contrações não inibidas do detrusor devido ao quadro de constipação intestinal, ou ainda a possibilidade de ser causada pelo quadro de infecção do trato urinário. Há três principais tratamentos disponíveis para tratar crianças com HV: medicação, uroterapia e eletroestimulação. Destes, a terapia medicamentosa ainda é a mais difundida pelo mundo, apesar de trazer diversos efeitos colaterais e baixa taxa de cura. A uroterapia é baseada em orientações miccionais e alimentares e deve ser indicada como a primeira linha terapêutica. A eletroestimulação ainda apresenta diversidade em relação à posição do eletrodo, tempo e frequência da aplicação e parâmetros diferentes em relação à corrente terapêutica. Apesar dessa variabilidade, as terapias combinadas da uroterapia com a eletroestimulação apresentam melhores resultados clínicos de acordo com os trabalhos disponíveis na literatura.


Author(s):  
David A. Ginsberg ◽  
Timothy B. Boone ◽  
Anne P. Cameron ◽  
Angelo Gousse ◽  
Melissa R. Kaufman ◽  
...  

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