scholarly journals Comparing effectiveness between a mobile application program and traditional cognitive behavior therapy in the treatment of obsessive-compulsive disorder (Preprint)

2020 ◽  
Author(s):  
Hyunchan Hwang ◽  
Sujin Bae ◽  
Jisun Hong ◽  
Doug Hyun Han
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Behavior Therapy ◽  
Cognitive Behavior Therapy ◽  
Clinical Symptoms ◽  
Brain Connectivity ◽  
Brain Activity ◽  
Cognitive Behavior ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Significant Difference

BACKGROUND This study proposes a digital program for the treatment of mental illness that could increase motivation and learning outcomes for patients. Several studies have already applied this method by using an exposure and response prevention inspired serious game to treat patients with obsessive-compulsive disorder (OCD). OBJECTIVE We hypothesized that a mobile cognitive behavior therapy (CBT) program would be effective in treating OCD as much as traditional offline CBT. In addition, the treatment efficacy in response to mobile CBT for OCD might be associated with increased brain activity within the cortico-striato-thalamo-cortical (CSTC) tract. METHODS The digital CBT treatment program for OCD, OCfree, consists of 6 education sessions, 10 quests, and 7 casual games. The information of 27 patients with OCD (15 offline CBT and 12 OCFree CBT) were gathered. During the 6-week intervention period, changes in the clinical symptoms and brain function activity were analyzed. RESULTS There was no significant difference in the change in OCD symptoms and depressive symptoms between the two groups. However, the OCfree group showed greater improvement in anxiety symptoms compared to the offline CBT group. Both offline CBT and OCfree CBT increased the functional connectivity within the CSTC tract in all patients with OCD. However, CBT using OCfree showed greater changes in brain connectivity within the thalamus and insula, compared to offline CBT. CONCLUSIONS : The OC free, an OCD treatment App program, was effective in the treatment of drug-naïve patients with OCD. The treatment effects of OCfree are associated with increased brain connectivity within the CSTC tract. Multisensory stimulation by education, quest, and games in OCfree increases the activity within the thalamus and insula in patients with OCD. CLINICALTRIAL

Effect of religious cognitive- behavior therapy on religious content obsessive compulsive disorder and marital satisfaction

2011 ◽  
Vol 26 (S2) ◽  
pp. 1742-1742 ◽  
Author(s):  
V. Omranifard ◽  
S. Akuchakian ◽  
A. Almasi ◽  
M.R. Maraci
Keyword(s):  
Marital Satisfaction ◽  
Obsessive Compulsive Disorder ◽  
Behavior Therapy ◽  
Cognitive Behavior Therapy ◽  
Repeated Measure ◽  
Controlled Clinical Trial ◽  
Cognitive Behavior ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Significant Difference

ObjectiveReligious themes commonly feature in religious with Obsessive-compulsive disorder (OCD). OCD which includes cognitive, emotional, and behavioral components, is a debilitating chronic disorder and can affects on patient’ marital satisfaction. The aim of us was to evaluate efficacy of Religious Cognitive- Behavior therapy (RCBT) on religious oriented Obsessive-Compulsive disorder and marital satisfaction.MethodThis is a randomized controlled clinical trial. This study conducted on 90 OCD outpatients with 17 and more Yale Brown obsessive compulsive scale(Y-BOCS) and religious content OCD. Intervention consists of 10 weekly RCBT. We used Enrich scale for asses’ marital satisfaction and Y-BOCS scale before and after treatment.Data were analyzed by ANCOVA/ANOVA repeated measure test using SPSS version ver.15.ResultIn our study duration of OCD was 11.5 ± 8.6 years & 11.5 ± 8.8 years and duration of marriage was 16.88 ± 11.6 & 13.51 ± 10.9 years Yale Brown scores after intervention decreased with significant difference (p = 0.001). There were significant difference between mean scores of two groups (p = 0.001). Comparison of obsession subscale and compulsion subscale of Yale Brown scale showed decreasing trend in both of obsession subscale and compulsion either within or between group is statistically significant (p = 0.001).Also marital satisfaction significantly improved in case group (p = 0.001).ConclusionIn religious patients with religious contents, religious based interventions like religious CBT could significantly increase clinical responses. Also theses interventions could improve marital status. These results suggest that Religious Cognitive-Behavior Therapy can be effective for religious oriented OCD patients.

scholarly journals “On My Own, but Not Alone” - Adolescents’ Experiences of Internet-Delivered Cognitive Behavior Therapy for Obsessive-Compulsive Disorder

PLoS ONE ◽  
2016 ◽  
Vol 11 (10) ◽  
pp. e0164311 ◽  
Author(s):  
Fabian Lenhard ◽  
Sarah Vigerland ◽  
Hedvig Engberg ◽  
Anna Hallberg ◽  
Hanna Thermaenius ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Behavior Therapy ◽  
Cognitive Behavior Therapy ◽  
Cognitive Behavior ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

Exposure and Ritual Prevention, Clomipramine, or Their Combination for Obsessive-Compulsive Disorder

2018 ◽  
Author(s):  
Brandon M. Kitay ◽  
Michael H. Bloch
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Behavior Therapy ◽  
Cognitive Behavior Therapy ◽  
Clinical Management ◽  
Clinical Case ◽  
Cognitive Behavior ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Landmark Study

This chapter provides a summary of a landmark study on the management of obsessive-compulsive disorder (OCD) in adults. Is the combination of exposure and ritual prevention (a cognitive behavior therapy based intervention) along with clomipramine more efficacious than monotherapy with either treatment for OCD? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study design, study interventions, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications for clinical management, and concludes with an exemplary clinical case applying the evidence.

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