Pneumatosis Intestinalis and Bowel Perforation Associated With Molecular Targeted Therapy: An Emerging Problem and the Role of Radiologists in Its Management

2012 ◽  
Vol 199 (6) ◽  
pp. 1259-1265 ◽  
Author(s):  
Atul B. Shinagare ◽  
Stephanie A. Howard ◽  
Katherine M. Krajewski ◽  
Katherine A. Zukotynski ◽  
Jyothi P. Jagannathan ◽  
...  
Keyword(s):  
Targeted Therapy ◽  
Molecular Targeted Therapy ◽  
Bowel Perforation ◽  
Pneumatosis Intestinalis

scholarly journals Role of Small Molecule Targeted Compounds in Cancer: Progress, Opportunities, and Challenges

2021 ◽  
Vol 9 ◽  
Author(s):  
Guoqiang Sun ◽  
Dawei Rong ◽  
Zhouxiao Li ◽  
Guangshun Sun ◽  
Fan Wu ◽  
...  
Keyword(s):  
Immune Response ◽  
Drug Resistance ◽  
Targeted Therapy ◽  
Drug Administration ◽  
Small Molecule ◽  
Molecular Targeted Therapy ◽  
Low Cost ◽  
Future Directions ◽  
Clinical Drug

Research on molecular targeted therapy of tumors is booming, and novel targeted therapy drugs are constantly emerging. Small molecule targeted compounds, novel targeted therapy drugs, can be administered orally as tablets among other methods, and do not draw upon genes, causing no immune response. It is easily structurally modified to make it more applicable to clinical needs, and convenient to promote due to low cost. It refers to a hotspot in the research of tumor molecular targeted therapy. In the present study, we review the current Food and Drug Administration (FDA)-approved use of small molecule targeted compounds in tumors, summarize the clinical drug resistance problems and mechanisms facing the use of small molecule targeted compounds, and predict the future directions of the evolving field.

The role of immunotherapy and molecular‑targeted therapy in the treatment of melanoma (Review)

2021 ◽  
Vol 46 (2) ◽  
Author(s):  
Paulina Stachyra‑Strawa ◽  
Marzanna Ciesielka ◽  
Michał Janiszewski ◽  
Ludmiła Grzybowska‑Szatkowska
Keyword(s):  
Targeted Therapy ◽  
Molecular Targeted Therapy

scholarly journals The role of cytoreductive nephrectomy in the era of molecular targeted therapy

2009 ◽  
Vol 16 (3) ◽  
pp. 227-233 ◽  
Author(s):  
Anthony J Polcari ◽  
Alex Gorbonos ◽  
John E Milner ◽  
Robert C Flanigan
Keyword(s):  
Targeted Therapy ◽  
Molecular Targeted Therapy ◽  
Cytoreductive Nephrectomy

Pneumatosis Intestinalis After Molecular-Targeted Therapy

2019 ◽  
Vol 125 ◽  
pp. 312-315 ◽  
Author(s):  
Nauman S. Chaudhry ◽  
Wenya Linda Bi ◽  
Saksham Gupta ◽  
Abhishek Keraliya ◽  
Naomi Shimizu ◽  
...  
Keyword(s):  
Targeted Therapy ◽  
Molecular Targeted Therapy ◽  
Pneumatosis Intestinalis

scholarly journals The Role of Cancer Genes in Thyroid Cancer and Molecular Targeted Therapy

2009 ◽  
Vol 98 (8) ◽  
pp. 1999-2005 ◽  
Author(s):  
Norisato Mitsutake ◽  
Shunichi Yamashita
Keyword(s):  
Thyroid Cancer ◽  
Targeted Therapy ◽  
Molecular Targeted Therapy ◽  
Cancer Genes
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