scholarly journals Kajian Sifat Dielektrik pada Lempeng Nanopartikel Magnetit (Fe3O4) yang dienkapsulasi dengan Polyvinyl Alcohol (PVA) (Halaman 34 s.d. 37)

2015 ◽  
Vol 19 (55) ◽  
Author(s):  
Mustawarman ◽  
Heriansyah ◽  
Edi Suharyadi

Telah dilakukan sintesis nanopartikel Fe3O4 yang kemudian dienkapsulasi dengan Polyvinyl alcohol (PVA) dengan perbandingan 1:0, 1:3, 1:4, 1:5 dan 1:6 menggunakan metode kopresipitasi. Pengukuran dilakukan menggunakan sistem spektroskopi impedansi terkomputerisasi pada wilayah frekuensi 10 kHz  hingga 120 kHz untuk mengetahui sifat dielektrik dari nanopartikel. Hasil pengukuran sifat dielektrik menunjukkan nilai permitivitas dielektrik pada seluruh sampel mengalami penurunan dengan bertambahnya frekuensi. Penambahan PVA mempengaruhi sifat dielektrik dari nanopartikel Fe3O4. Nilai permitivitas dielektrik riil  seluruh sampel secara berturut-turut pada frekuensi 10 kHz yaitu 522, 212, 36, 234 dan 692.  Nilai permitivitas dielektrik yang paling baik adalah nanopartikel Fe3O4+PVA (1:6 ) sehingga dapat digunakan untuk aplikasi biosensor Surface Plasmon Resonance(SPR) sebagai bahan aktif untuk meningkatkan sensitifitas sensor dan mengikat biomolekuler.

2017 ◽  
Vol 2017 ◽  
pp. 1-11 ◽  
Author(s):  
Mauricio E. Di Ianni ◽  
Germán A. Islan ◽  
Cecilia Y. Chain ◽  
Guillermo R. Castro ◽  
Alan Talevi ◽  
...  

The applications of pharmaceutical and medical nanosystems are among the most intensively investigated fields in nanotechnology. A relevant point to be considered in the design and development of nanovehicles intended for medical use is the formation of the “protein corona” around the nanoparticle, that is, a complex biomolecular layer formed when the nanovehicle is exposed to biological fluids. The chemical nature of the protein corona determines the biological identity of the nanoparticle and influences, among others, the recognition of the nanocarrier by the mononuclear phagocytic system and, thus, its clearance from the blood. Recent works suggest that Surface Plasmon Resonance (SPR), extensively employed for the analysis of biomolecular interactions, can shed light on the formation of the protein corona and its interaction with the surroundings. The synthesis and characterization of solid lipid nanoparticles (SLN) coated with polymers of different chemical nature (e.g., polyvinyl alcohol, chitosans) are reported. The proof-of-concept for the use of SPR technique in characterizing protein-nanoparticle interactions of surface-immobilized proteins (immunoglobulin G and bovine serum albumin, both involved in the formation of the corona) subjected to flowing SLN is demonstrated for non-chitosan-coated nanoparticles. All assayed nanosystems show more preference for IgG than for BSA, such preference being more pronounced in the case of polyvinyl-alcohol-coated SLN.


Biosensors ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 461
Author(s):  
Ying Wang ◽  
Jingru Wang ◽  
Yu Shao ◽  
Changrui Liao ◽  
Yiping Wang

A surface-plasmon-resonance-based fiber device is proposed for highly sensitive relative humidity (RH) sensing and human breath monitoring. The device is fabricated by using a polyvinyl alcohol (PVA) film and gold coating on the flat surface of a side-polished polymer optical fiber. The thickness and refractive index of the PVA coating are sensitive to environmental humidity, and thus the resonant wavelength of the proposed device exhibits a redshift as the RH increases. Experimental results demonstrate an average sensitivity of 4.98 nm/RH% across an ambient RH ranging from 40% to 90%. In particular, the sensor exhibits a linear response between 75% and 90% RH, with a sensitivity of 10.15 nm/RH%. The device is suitable for human breath tests and shows an average wavelength shift of up to 228.20 nm, which is 10 times larger than that of a silica-fiber-based humidity sensor. The corresponding response and recovery times are determined to be 0.44 s and 0.86 s, respectively. The proposed sensor has significant potential for a variety of practical applications, such as intensive care and human health analysis.


2020 ◽  
pp. 44-49
Author(s):  
I. N. Pavlov

Two optical methods, namely surface plasmon resonance imaging and frustrated total internal reflection, are described in the paper in terms of comparing their sensitivity to change of refractive index of a thin boundary layer of an investigated medium. It is shown that, despite the fact that the theoretically calculated sensitivity is higher for the frustrated total internal reflection method, and the fact that usually in practice the surface plasmon resonance method, on the contrary, is considered more sensitive, under the same experimental conditions both methods show a similar result.


2010 ◽  
Vol 130 (7) ◽  
pp. 269-274 ◽  
Author(s):  
Takeshi Onodera ◽  
Takuzo Shimizu ◽  
Norio Miura ◽  
Kiyoshi Matsumoto ◽  
Kiyoshi Toko

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