scholarly journals ADULT ONSET HENOCH: SCHONLEIN PURPURA – AN UNUSUAL PRESENTATION

2017 ◽  
Vol 10 (10) ◽  
pp. 2
Author(s):  
Srujith Chandrakanti ◽  
Oshin Mantro ◽  
Jagadeesan Mohanan ◽  
Mervin Kayipirambil Soman ◽  
Prasanna Karthik Suthakaran ◽  
...  
Keyword(s):  
Rare Case ◽  
Early Recognition ◽  
Leukocytoclastic Vasculitis ◽  
Renal Involvement ◽  
Unusual Presentation ◽  
Organ Involvement ◽  
Adult Onset ◽  
Henoch Schonlein Purpura ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

  Henoch–Schonlein purpura (HSP) is a common leukocytoclastic vasculitis seen in children. However, it is uncommon in adults. HSP is characterized by the classic tetrad of non-thrombocytopenic palpable purpura, arthritis or arthralgias, gastrointestinal, and renal involvement. We report a rare case of adult onset HSP with multi-organ involvement. Early recognition of multi-organ involvement is very important, especially in adults.

scholarly journals Henoch-Schonlein Purpura—A Case Report and Review of the Literature

2010 ◽  
Vol 2010 ◽  
pp. 1-7 ◽  
Author(s):  
Amit B. Sohagia ◽  
Srinivas Guptha Gunturu ◽  
Tommy R. Tong ◽  
Hilary I. Hertan
Keyword(s):  
Early Recognition ◽  
Leukocytoclastic Vasculitis ◽  
Systemic Disease ◽  
Renal Involvement ◽  
Symptomatic Treatment ◽  
Adolescent Male ◽  
Small Vessel Vasculitis ◽  
Henoch Schonlein Purpura ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

We describe a case of an adolescent male with Henoch-Schonlein purpura (HSP), presenting with cutaneous and gastrointestinal manifestations. Endoscopy revealed diffuse ulcerations in the stomach, duodenum, and right colon. Biopsies revealed a leukocytoclastic vasculitis in the skin and gastrointestinal tract. Steroid therapy led to complete resolution of the symptoms. HSP is the most common childhood vasculitis, and is characterized by the classic tetrad of nonthrombocytopenic palpable purpura, arthritis or arthralgias, gastrointestinal and renal involvement. It is a systemic disease where antigen-antibody (IgA) complexes activate the alternate complement pathway, resulting in inflammation and small vessel vasculitis. Mild disease resolves spontaneously, and symptomatic treatment alone is sufficient. Systemic steroids are recommended for moderate to severe HSP. The prognosis depends upon the extent of renal involvement, which requires close followup. Early recognition of multiorgan involvement, especially outside of the typical age group, as in our adolescent patient, and appropriate intervention can mitigate the disease and limit organ damage.

scholarly journals Henoch-Schönlein Purpura Nephritis in Children: A Review

2014 ◽  
Vol 38 (1) ◽  
pp. 24-31
Author(s):  
Golam Muin Uddin ◽  
Afroza Begum
Keyword(s):  
Leukocytoclastic Vasculitis ◽  
Treatment Options ◽  
Renal Involvement ◽  
Henoch Schonlein Purpura ◽  
Multiple Organs ◽  
Systemic Disorder ◽  
Stage Renal Disease ◽  
End Stage ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

Henoch-Schönlein purpura (HSP) is a systemic disorder which involves multiple organs including kidney. The characteristic pathology is leukocytoclastic vasculitis of the capillaries with deposition of IgA immune complexes. The principal cause of morbidity and mortality in this disease is due to renal involvement. Approximately half of the children with HSP develop nephritis (HSPN) within 4-6 weeks of initial presentation and HSPN is a major cause of end stage renal disease (ESRD) in children. So, it is important to be updated about aetio-pathogensis, clinico-pathological aspects and prognostic factors of nephritis related to Henoch Schonlein purpura. The most important is to identify the appropriate treatment options for HSPN. So, herein review has been done on the different aspects of HSPN including treatment. DOI: http://dx.doi.org/10.3329/bjch.v38i1.20024 Bangladesh J Child Health 2014; VOL 38 (1) : 24-31

scholarly journals An adult male with abdominal pain and skin rash

2014 ◽  
Vol 3 (9) ◽  
pp. 38
Author(s):  
Jay Patel ◽  
Imran Umer ◽  
Anand Reddy ◽  
Yasir Ahmed ◽  
Craig Spellman
Keyword(s):  
Renal Failure ◽  
Skin Rash ◽  
Leukocytoclastic Vasculitis ◽  
Gastrointestinal Symptoms ◽  
Adult Onset ◽  
Henoch Schonlein Purpura ◽  
Long Term Prognosis ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

Henoch-Schönlein purpura is generally a disease of children and uncommon in adults, especially after the age of 40. It is characterized by leukocytoclastic vasculitis skin rash, arthralgia, and gastrointestinal symptoms. In adults, glomerulonephritis may occur and the long-term prognosis is poor. We present the case of a 65-year-old man with complaints of abdomen pain and skin rash who subsequently developed renal failure. He was diagnosed with adult onset Henoch-Schönlein purpura and survived after treatment with glucocorticoids and hemodialysis.

scholarly journals 119 Location of skin lesions in Henoch-Schonlein purpura (HSP) and its association with renal involvement

2016 ◽  
Vol 136 (5) ◽  
pp. S22
Author(s):  
J. St. John ◽  
A. Garza-Mayers ◽  
P. Vedak ◽  
M. Hoang ◽  
S. Nigwekar ◽  
...  
Keyword(s):  
Renal Involvement ◽  
Skin Lesions ◽  
Henoch Schonlein Purpura ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

Adult-onset malignancy-associated Henoch–Schönlein purpura

2011 ◽  
Vol 40 (4) ◽  
pp. 325-326 ◽  
Author(s):  
AN Flynn ◽  
B du Prey ◽  
H Al Ardati ◽  
M Raman ◽  
J Lemaire
Keyword(s):  
Adult Onset ◽  
Henoch Schonlein Purpura ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

A rare case of Henoch-Schönlein purpura with neurological involvement

2010 ◽  
Vol 40 (11) ◽  
pp. 795-796 ◽  
Author(s):  
E. Fiaux ◽  
Y. Benhamou ◽  
N. Cailleux ◽  
H. Levesque
Keyword(s):  
Rare Case ◽  
Neurological Involvement ◽  
Henoch Schonlein Purpura ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura
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