Ultrasound imaging and guidance in peripheral nerve entrapment: hydrodissection highlighted

2020 ◽  
Vol 10 (2) ◽  
pp. 97-106 ◽  
Author(s):  
Ke-Vin Chang ◽  
Wei-Ting Wu ◽  
Levent Özçakar

Ultrasound (US) imaging has become one of the most useful modalities to assess peripheral nerve disorders. Nowadays, it is as important as nerve conduction studies and electromyography for peripheral nerve entrapment. Additionally, US is also helpful in guiding a possible intervention. As peripheral nerves are tiny, palpation-guided injections are really challenging for precisely targeting the nerves. By using US, perineural injections have significantly become safe and effective. Recently, US-guided hydrodissection has emerged as the mainstream for nerve entrapment. Accordingly, this review aims to summarize and update the mechanism and evidence regarding this imperative procedure for neuropathic pain management. Furthermore, the pathogenesis, anatomic features, US findings and histological correlations of nerve entrapment syndromes will also be discussed in this article.

2021 ◽  
pp. 261-263
Author(s):  
Arup Mallik

Neurophysiology is a useful investigation to assess peripheral nerve injury. It consists of nerve conduction studies and electromyography, providing information on anatomical distribution of the lesion (pre/postganglionic, single/multiple nerves), whether the lesion is primarily demyelinating or axonal, and whether the lesion is in continuity, as well as the overall prognosis.


Author(s):  
Bashar Katirji

Neuromuscular disorders are often classified into four major categories: anterior horn cell disorders, peripheral neuropathies, neuromuscular junction disorders and myopathies. This chapter discusses the electrodiagnostic and clinical EMG findings in these various neuromuscular disorders. Peripheral neuropathies are subdivided into focal mononeuropathies, radiculopathies, plexopathies and generalized peripheral polyneuropathies. Focal peripheral nerve lesions and generalized peripheral polyneuropathies may be axonal or demyelinating, and manifest quite distinctly on nerve conduction studies. Neuromuscular junction disorders may be presynaptic, as seen with the Lambert-Eaton myasthenic syndrome, or postsynaptic, as seen with myasthenia gravis.


2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S107-S107
Author(s):  
Stacy A Hussong ◽  
Veronica Galvan

Abstract With age, peripheral nerves undergo demyelination along with overall decrease in peripheral nerve conduction velocity in both sensory and motor nerves. Loss of innervation in muscles is thought to be a major factor in causing age-related sarcopenia including a decrease in muscle function. Dietary restriction attenuates the detrimental effects of aging in mice. Reduction of mTOR signaling is hypothesized to have overlapping mechanisms with dietary restriction. Furthermore, inhibition of mTOR via rapamycin treatment is known to extend lifespan in mice as well as improve peripheral nerve myelination. Therefore, I hypothesized that reducing mTORC1 signaling in neurons would be able to ameliorate the deleterious effects of aging in peripheral nerves. An overall decrease in nerve conduction velocity was observed in both tail sensory and sural nerves with age (15 vs. 30 months). In neuronal mTORC1 KD animals, there was an age-related preservation of both sural and sciatic nerve conduction. Rapamycin treatment produced similar effects with a trend towards increased sciatic nerve conduction velocity in rapamycin-treated wild-type mice at 19 months. The preserve sciatic nerve conduction velocity could be partially explained by preserved myelination. Neuronal mTORC1 knockdown animals had more myelin in the sciatic nerve at 30 mo. as compared to age-matched controls. Overall, these data indicate that mTORC1 signaling plays a role in the age-related decline in peripheral nerve myelination as well as nerve conduction velocity. Future therapeutics could utilize rapamycin or other rapalogs to combat the decline in peripheral nerve function associated with age and other diseases as well.


2016 ◽  
Vol 35 (6) ◽  
pp. 1367-1368
Author(s):  
Jonathan K. Smith ◽  
Matthew E. Miller ◽  
David E. Reece ◽  
Yin-Ting Chen ◽  
Mark E. Landau

Ból ◽  
2019 ◽  
Vol 19 (4) ◽  
pp. 59-62
Author(s):  
Osman Chaudhary ◽  
Teodor Goroszeniuk ◽  
Christopher Chan

Chronic pain attributed to the abdominal wall is seen in 10-30% of patients who present to specialist pain clinics [24]. The most common cause is abdominal cutaneous nerve entrapment syndrome (ACNES). Trauma, including surgical incisions and tissue scarring, are well accepted causes of cutaneous nerve entrapment causing neuropathic pain [24]. The occurrence of peristomal neuropathic pain associated with an ileal-conduit formation is rare. A case of chronic cutaneous peristomal pain of the abdominal wall, refractory to conventional pharmacological therapies is described. The technique of peripheral nerve field stimulation (PNFS) for the successful management of peristomal neuropathic abdominal wall pain is reported.


2014 ◽  
Vol 5 (3) ◽  
pp. 64-66
Author(s):  
Marina Nikolayevna Romanova ◽  
Nikolay Grigoryevich Zhila ◽  
Yelena Vladimirovna Sinelnikova

Ultrasound imaging of peripheral nerves can accurately determine the level of damage, and also to assess the extent of damage to the structure of the nerve fiber. Early detection of the type of damage can significantly improve patient outcomes.


2009 ◽  
Vol 26 (2) ◽  
pp. E13 ◽  
Author(s):  
Ralph W. Koenig ◽  
Maria T. Pedro ◽  
Christian P. G. Heinen ◽  
Thomas Schmidt ◽  
Hans-Peter Richter ◽  
...  

High-resolution ultrasonography is a noninvasive, readily applicable imaging modality, capable of depicting real-time static and dynamic morphological information concerning the peripheral nerves and their surrounding tissues. Continuous progress in ultrasonographic technology results in highly improved spatial and contrast resolution. Therefore, nerve imaging is possible to a fascicular level, and most peripheral nerves can now be depicted along their entire anatomical course. An increasing number of publications have evaluated the role of high-resolution ultrasonography in peripheral nerve diseases, especially in peripheral nerve entrapment. Ultrasonography has been shown to be a precious complementary tool for assessing peripheral nerve lesions with respect to their exact location, course, continuity, and extent in traumatic nerve lesions, and for assessing nerve entrapment and tumors. In this article, the authors discuss the basic technical considerations for using ultrasoniography in peripheral nerve assessment, and some of the clinical applications are illustrated.


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