scholarly journals The effects of vitamin D supplementation on endogen amylin hormone, hormonal and biochemical parameters, and insulin resistance in type-2 diabetic patients with vitamin D deficiency in the Kurdistan Region of Iraq

2019 ◽  
Vol 60 (4) ◽  
pp. 310-318
Author(s):  
Mudhafar Mohamed M. Saeed ◽  
◽  
Abdulqader Azeez Al-Naqshabandi ◽  
Hawri Fatih Sami Aldawoodi ◽  
◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Biochemical Parameters ◽  
Vitamin D Supplementation ◽  
Diabetic Patients ◽  
Kurdistan Region ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic

scholarly journals Effect of Vitamin D supplementation on vascular functions and oxidative stress in type 2 diabetic patients with Vitamin D deficiency

2017 ◽  
Vol 21 (4) ◽  
pp. 555 ◽  
Author(s):  
Sandhiya Selvarajan ◽  
Nishanthi Anandabaskar ◽  
StevenAibor Dkhar ◽  
SadishKumar Kamalanathan ◽  
Kadhiravan Tamilarasu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Vitamin D Supplementation ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
And Oxidative Stress ◽  
Type 2 Diabetic

Vitamin D3 supplementation improves glycemic control in type 2 diabetic patients: Results from an Italian clinical trial

2020 ◽  
pp. 1-10
Author(s):  
Giuseppe Derosa ◽  
Angela D’Angelo ◽  
Chiara Martinotti ◽  
Maria Chiara Valentino ◽  
Sergio Di Matteo ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Metabolic Control ◽  
Vitamin D3 ◽  
Therapy Group ◽  
Hypoglycemic Agents ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic

Abstract. Background: to evaluate the effects of Vitamin D3 on glyco-metabolic control in type 2 diabetic patients with Vitamin D deficiency. Methods: one hundred and seventeen patients were randomized to placebo and 122 patients to Vitamin D3. We evaluated anthropometric parameters, glyco-metabolic control, and parathormone (PTH) value at baseline, after 3, and 6 months. Results: a significant reduction of fasting, and post-prandial glucose was recorded in Vitamin D3 group after 6 months. A significant HbA1c decrease was observed in Vitamin D3 (from 7.6% or 60 mmol/mol to 7.1% or 54 mmol) at 6 months compared to baseline, and to placebo (p < 0.05 for both). At the end of the study period, we noticed a change in the amount in doses of oral or subcutaneous hypoglycemic agents and insulin, respectively. The use of metformin, acarbose, and pioglitazone was significantly lower (p = 0.037, p = 0.048, and p = 0.042, respectively) than at the beginning of the study in the Vitamin D3 therapy group. The units of Lispro, Aspart, and Glargine insulin were lower in the Vitamin D3 group at the end of the study (p = 0.031, p = 0.037, and p = 0.035, respectively) than in the placebo group. Conclusions: in type 2 diabetic patients with Vitamin D deficiency, the restoration of value in the Vitamin D standard has led not only to an improvement in the glyco-metabolic compensation, but also to a reduced posology of some oral hypoglycemic agents and some types of insulin used.

scholarly journals Analysis of the Associations between Vitamin D and Albuminuria orβ-Cell Function in Chinese Type 2 Diabetes

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Xiaoling Cai ◽  
Zhaoheng Hu ◽  
Ling Chen ◽  
Xueyao Han ◽  
Linong Ji
Keyword(s):  
Insulin Resistance ◽  
Vitamin D ◽  
Cell Function ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Albumin Creatinine Ratio ◽  
Urine Albumin ◽  
Vitamin D Supplement ◽  
Type 2 Diabetic

Objective. To investigate the associations of 25-(OH)D andβ-cell function or insulin resistance or albuminuria in Chinese type 2 diabetic patients.Methods. In total, 1408 type 2 diabetic patients without vitamin D supplement were included in this retrospective study.Results. Comparison between patients with and without 25-(OH)D deficiency indicated that, compared with patients with 25-(OH)D ≥ 50 nmol/L, patients with 25-(OH)D < 50 nmol/L showed a higher level of urine albumin-creatinine ratio (ACR) (90.15±10.30 mg/g versus52.79±14.97 mg/g). Multiple regression analysis indicated that 25-(OH)D was independently and negatively correlated with urine ACR (OR=0.985, 95%CI 0.972–0.999,P=0.03), adjusted by age, diabetic duration, HBP duration, SBP, HbA1c, creatinine, LDL-C, triglyceride, total cholesterol, and HDL-C. Compared with patients with normal level of urine ACR, patients with higher level of urine ACR showed a significant lower level of 25-(OH)D (34.49±13.52 nmol/L versus37.46±13.6 nmol/L,P=0.00). Analysis of the associations of 25-(OH)D andβ-cell function or insulin resistance showed that 25-(OH)D may not correlate withβ-cell function or insulin resistance.Conclusion. 25-(OH)D was independently associated with albuminuria in Chinese type 2 diabetic patients but was not associated withβ-cell function or insulin resistance.

scholarly journals Effects of 12-month, 2000IU/day vitamin D supplementation on treatment naïve and vitamin D deficient Saudi type 2 diabetic patients

2015 ◽  
Vol 36 (12) ◽  
pp. 1432-1438 ◽  
Author(s):  
May Al-Shahwan ◽  
Abdulaziz Al-Othman ◽  
Nasser Al-Daghri ◽  
Shaun Sabico
Keyword(s):  
Vitamin D ◽  
Vitamin D Supplementation ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Treatment Naïve ◽  
Type 2 Diabetic

scholarly journals Vitamin D Deficiency Among Type 2 Diabetic Patients in Najran Area, Saudi Arabia.

2020 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Omar Mohamed ◽  
Amar Elhussein ◽  
Walid Babikr ◽  
Mariam AlSayed
Keyword(s):  
Vitamin D ◽  
Saudi Arabia ◽  
Vitamin D Deficiency ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic
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