Application of a new hyperbaric oxygen therapy protocol in patients with arterial and venous gas embolism due to hydrogen peroxide poisoning

2021 ◽  
pp. 187-193
Author(s):  
Je-seop Lee ◽  
◽  
Youn Sung Cha ◽  

Hydrogen peroxide (H2O2) ingestion can cause vascular gas embolism (GE). Hyperbaric oxygen therapy (HBO2) is known to improve neurological abnormalities in patients with arterial gas embolism (AGE). Previously, HBO2 based on the U.S. Navy Table 6 diving protocol has been adopted for treating AGE and preventing the progression of portal venous GE, caused by H2O2 ingestion, to AGE. However, the indication and protocol for HBO2 have not been established for GE related to H2O2 ingestion. Herein, we describe a case in which GE caused by H2O2 ingestion was treated using HBO2 with a short protocol. A 69-year-old female patient presented with abdominal pain, vomiting, and transient loss of consciousness after ingesting 35% H2O2. Computed tomography revealed gastric wall and portal venous gas. She was administered an HBO2 protocol with 2.8-atmosphere absolute (ATA) compression for 45 minutes. This was followed by a 2.0-ATA treatment for 60 minutes with a five-minute air break, after which all gas bubbles disappeared. After HBO2 treatment, brain magnetic resonance imaging revealed focal cytotoxic edema lesions; however, the patient was discharged without additional symptoms.

2021 ◽  
pp. 177-186
Author(s):  
Stella Pak ◽  
◽  
Christopher Lee ◽  
Joseph Lach ◽  
George Ortiz ◽  
...  

A 52-year-old male accidentally ingested approximately 100 mL of 35% hydrogen peroxide (H2O2), resulting in the sudden onset of gastrointestinal and neurologic symptoms. Non-contrast abdominal CT revealed extensive portal venous gas and gastric pneumatosis. The patient was treated with hyperbaric oxygen therapy which resulted in complete resolution of symptoms. The case highlights the therapeutic value of hyperbaric oxygen therapy in the treatment of vascular gas embolism and mitigation of concentrated H2O2 ingestion toxicity.


2014 ◽  
Vol 46 (2) ◽  
pp. 171-175 ◽  
Author(s):  
Brendan Byrne ◽  
Robert Sherwin ◽  
Cheryl Courage ◽  
Alfred Baylor ◽  
Bram Dolcourt ◽  
...  

2017 ◽  
Vol 35 (5) ◽  
pp. 809.e5-809.e8 ◽  
Author(s):  
Stephen M. Hendriksen ◽  
Nicholas L Menth ◽  
Bjorn C. Westgard ◽  
Jon B. Cole ◽  
Joseph W. Walter ◽  
...  

2020 ◽  
Vol 81 (3) ◽  
pp. 96
Author(s):  
Ana Margarida Fernandes ◽  
Tatiana Fonseca ◽  
Ana Isabel Paixão ◽  
Paula Castelões

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Giorgio Berlot ◽  
Adriano Rinaldi ◽  
Marco Moscheni ◽  
Massimo Ferluga ◽  
Perla Rossini

Many different risk factors have been associated with the occurrence of gas embolism making this potentially lethal complication easily avoidable. However, this condition can occur in circumstances not commonly reported. Three different and extremely uncommon cases of gas embolism are presented and discussed: the first was caused by the voluntary ingestion of hydrogen peroxide, the second occurred during a retrograde cholangiopancreatography, and the last followed the intrapleural injection of Urokinase. Whereas in the first patient the gas embolism was associated with only relatively mild digestive symptoms, in the remaining two it caused a massive cerebral ischemia and an extended myocardial infarction, respectively. Despite a hyperbaric oxygen therapy performed timely in each case, only the first patient survived. The classical risk factors associated with gas embolism like indwelling central venous catheters, diving accidents, etc. are rather well known and thus somewhat preventable; however, a number of less common and difficult-to-recognize causes can determine this condition, making the correct diagnosis elusive and delaying the hyperbaric oxygen therapy, whose window of opportunity is rather narrow. Thus, a gas embolism should be suspected in the presence of not otherwise explainable sudden neurologic and/or cardiovascular symptoms also in circumstances not typically considered at risk.


2019 ◽  
Vol 68 (7) ◽  
pp. 456-460
Author(s):  
L. Hellinger ◽  
A. M. Keppler ◽  
H. Schoeppenthau ◽  
J. Perras ◽  
R. Bender

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