Are superoxide and/or hydrogen peroxide responsible for some of the beneficial effects of hyperbaric oxygen therapy?

2001 ◽  
Vol 57 (6) ◽  
pp. 764-769 ◽  
Author(s):  
J. Hink ◽  
E. Jansen
2021 ◽  
pp. 177-186
Author(s):  
Stella Pak ◽  
◽  
Christopher Lee ◽  
Joseph Lach ◽  
George Ortiz ◽  
...  

A 52-year-old male accidentally ingested approximately 100 mL of 35% hydrogen peroxide (H2O2), resulting in the sudden onset of gastrointestinal and neurologic symptoms. Non-contrast abdominal CT revealed extensive portal venous gas and gastric pneumatosis. The patient was treated with hyperbaric oxygen therapy which resulted in complete resolution of symptoms. The case highlights the therapeutic value of hyperbaric oxygen therapy in the treatment of vascular gas embolism and mitigation of concentrated H2O2 ingestion toxicity.


2018 ◽  
Vol 62 (1) ◽  
pp. 75-83
Author(s):  
Gabriela Henrykowska ◽  
Andrzej Buczyński ◽  
Małgorzata Lewicka ◽  
Magdalena Zawadzka

Abstract During the last decades, there has been a rapid development in the research and use of hyperbaric oxygen therapy (HBO), and modern medicine is increasingly taking advantage of its beneficial effects. The aim of the study was to check the level of knowledge of future doctors (medical students) on hyperbaric oxygen therapy. The survey was conducted among 240 students of the medical faculty (3rd and 5th year of study) of the Military and Medical Faculty of the Medical University of Lodz. The author’s questionnaire with forced-choice questions was used as research tool. The students’ knowledge of hyperbaric oxygen therapy was varied and in some cases was not dependent on the year of study. It was observed that students’ knowledge of the subject matter depends on the number of teaching hours allocated to it.


NSC Nursing ◽  
2021 ◽  
pp. 1-22
Author(s):  
Vincenza Giordano ◽  
Luca Cardillo

Introduction: Fournier's Gangrene is a severe necrotising infection that can be fatal if not recognised and treated immediately. Treatment consists of a combination of conventional therapy with a multidisciplinary approach (early diagnosis, surgical debridement, antibiotic therapy, intensive care and reconstructive surgery) and adjuvant therapy with hyperbaric oxygen therapy sessions. Objective: To identify the role and evaluate the efficacy of hyperbaric oxygen therapy in Fournier's gangrene. Method: To conduct the following narrative review a research question was outlined using the PIO methodology. Subsequently, a literature review was conducted using the PubMed, Scopus and CINAHL Complete databases from December 2020 to February 2021. Results: Eight studies emerged from the literature review showing that the use of adjuvant Hyperbaric oxygen therapy (HBOT) in combination with classical treatment has beneficial effects and enhances the efficacy of hyperbaric oxygen therapy, resulting in lower mortality rates, in contrast to the average number of hospital days spent in intensive care, which do not undergo any significant change. But in contrast to mortality, the average number of days spent in intensive care differed significantly in favour of the standard treatment group. Conclusion: The combined effect of hyperbaric oxygen therapy with conventional therapy offers a significant advantage in the management of FG; furthermore, HBOT is associated with a significant survival advantage. Keywords: Fournier's gangrene, Fournier's disease, Hyperbaric oxygen therapy and HBOT


2014 ◽  
Vol 46 (2) ◽  
pp. 171-175 ◽  
Author(s):  
Brendan Byrne ◽  
Robert Sherwin ◽  
Cheryl Courage ◽  
Alfred Baylor ◽  
Bram Dolcourt ◽  
...  

2002 ◽  
Vol 11 (2) ◽  
pp. 95-101 ◽  
Author(s):  
Jyuhn-Huarng Juang ◽  
Brend Ray-Sea Hsu ◽  
Chien-Hung Kuo ◽  
Steve Wen-Neng Ueng

2021 ◽  
pp. 187-193
Author(s):  
Je-seop Lee ◽  
◽  
Youn Sung Cha ◽  

Hydrogen peroxide (H2O2) ingestion can cause vascular gas embolism (GE). Hyperbaric oxygen therapy (HBO2) is known to improve neurological abnormalities in patients with arterial gas embolism (AGE). Previously, HBO2 based on the U.S. Navy Table 6 diving protocol has been adopted for treating AGE and preventing the progression of portal venous GE, caused by H2O2 ingestion, to AGE. However, the indication and protocol for HBO2 have not been established for GE related to H2O2 ingestion. Herein, we describe a case in which GE caused by H2O2 ingestion was treated using HBO2 with a short protocol. A 69-year-old female patient presented with abdominal pain, vomiting, and transient loss of consciousness after ingesting 35% H2O2. Computed tomography revealed gastric wall and portal venous gas. She was administered an HBO2 protocol with 2.8-atmosphere absolute (ATA) compression for 45 minutes. This was followed by a 2.0-ATA treatment for 60 minutes with a five-minute air break, after which all gas bubbles disappeared. After HBO2 treatment, brain magnetic resonance imaging revealed focal cytotoxic edema lesions; however, the patient was discharged without additional symptoms.


2017 ◽  
Vol 35 (5) ◽  
pp. 809.e5-809.e8 ◽  
Author(s):  
Stephen M. Hendriksen ◽  
Nicholas L Menth ◽  
Bjorn C. Westgard ◽  
Jon B. Cole ◽  
Joseph W. Walter ◽  
...  

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