scholarly journals Metastatic renal cell carcinoma complicated by right atrial thrombus

2021 ◽  
Author(s):  
Hafiz Jeelani ◽  
Muhammad Mubbashir Sheikh ◽  
Adeel Riaz ◽  
Nayha Tahir ◽  
Nikita Jain ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell ◽  
Renal Mass ◽  
Rare Event ◽  
Right Atrial ◽  
Imaging Studies ◽  
Atrial Thrombus ◽  
Right Atrial Thrombus

Metastasis of renal cell carcinoma to the heart is a rare event. Herein we present a case of renal cell carcinoma presenting with progressive fatigue, abdominal pain, and weight loss. Imaging studies revealed complex renal mass with extension to right atrium and histopathology confirmed the metastatic renal cell carcinoma.

scholarly journals Metastatic renal cell carcinoma complicated by right atrial thrombus

2021 ◽  
Author(s):  
Hafiz Muhammad Abrar Jeelani ◽  
Muhammad Mubbashir Sheikh ◽  
Adeel Riaz ◽  
Nikita Jain ◽  
Nayha Tahir ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell ◽  
Right Atrial ◽  
Atrial Thrombus ◽  
Right Atrial Thrombus

scholarly journals Metastatic renal cell carcinoma to the testis: A case report and review of the literature

2014 ◽  
Vol 8 (11-12) ◽  
pp. 924 ◽  
Author(s):  
Karim Marzouk ◽  
Fahad Alyami ◽  
Jennifer Merrimen ◽  
Scott Bagnell
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell ◽  
Renal Mass ◽  
Metastatic Lesion ◽  
Review Of The Literature ◽  
Computed Tomography Scan ◽  
Cytoreductive Nephrectomy ◽  
Tomography Scan

This is a case of a 68-year-old male who presented with a chief compliant of a testicular mass, which was discovered to be a metastatic lesion of undiagnosed renal cell carcinoma. A computed tomography scan revealed a large right renal mass and multiple pulmonary metastasis. Shortly after diagnosis, the patient was initiated on systemic therapy and received a cytoreductive nephrectomy. We discuss the details of this case as well as a pertinent review of metastatic renal cell carcinoma to the testes.

scholarly journals Metastatic renal cell carcinoma with undetectable renal mass presenting as lymphadenopathy

2016 ◽  
Vol 6 (1) ◽  
pp. 36-38 ◽  
Author(s):  
Mohamed Salah Fayaz ◽  
Aishah Ebrahim Al-Qaderi ◽  
Mustafa Shawki El-Sherify
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell ◽  
Renal Mass

scholarly journals Spontaneous Regression of Metastatic Renal Cell Carcinoma after SARS-CoV-2 Infection: A Report of Two Cases

2021 ◽  
Vol 28 (5) ◽  
pp. 3403-3407
Author(s):  
Tomas Buchler ◽  
Lukas Fiser ◽  
Jaroslava Benesova ◽  
Hana Jirickova ◽  
Jana Votrubova
Keyword(s):  
Renal Cell Carcinoma ◽  
Innate Immunity ◽  
Cell Carcinoma ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell ◽  
Spontaneous Regression ◽  
Rare Event ◽  
Morbidity And Mortality ◽  
Tumour Regression ◽  
Mediastinal Involvement

Spontaneous regression of metastatic renal cell carcinoma (mRCC) is a rare event, often associated with an activation of innate immunity by various triggers. SARS-CoV-2 infection induces a strong inflammatory response in some patients and a cytokine storm is one of the main causes of severe morbidity and mortality associated with the virus. Here, we describe two cases of patients with histologically and radiologically proven mRCC whose treatment was delayed due to COVID-19 and who experienced spontaneous tumour regression following the infection. Both patients reported here had predominantly pulmonary and mediastinal involvement and underwent nephrectomy. The interval between the diagnosis of COVID-19 and the detection of tumour regression was 3 and 4 months, respectively. Although approved vaccines and other measures are clearly the best way to prevent COVID-19-associated morbidity and mortality in cancer patients, we hypothesize that innate immunity activation by the infection can contribute to tumour regression in special circumstances.

Abscopal effect after hypofractionated radiotherapy in metastatic renal cell carcinoma pretreated with pazopanib

Immunotherapy ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 869-878 ◽  
Author(s):  
Luigi Cerbone ◽  
Sara Elena Rebuzzi ◽  
Elisabetta Lattanzi ◽  
Letizia Gnetti ◽  
Maria Laura Iaia ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell ◽  
Local Treatment ◽  
Rare Event ◽  
Hypofractionated Radiotherapy ◽  
Tumor Control ◽  
Abscopal Effect

Background: The abscopal effect consists of distant metastases response after local treatment based on systemic immune stimulation. It is a rare event observed in many tumors, especially with radiotherapy and immunotherapy. Clinical case: We report the long-term abscopal effect in a metastatic renal cell carcinoma patient with lung metastasectomy, after hypofractionated radiotherapy on lymph node metastasis. The patient was pretreated with pazopanib, which was discontinued early owing to toxicity before radiotherapy. Methodology: Immunohistological analyses of the primary tumor and metastases were performed. Discussion: We supposed that radiotherapy, and maybe tyrosine kinase inhibitors, could act as immune-primers for abscopal effect modifying the immune tumor microenvironment. Conclusion: Future studies are needed to optimize the combination of radiotherapy with systemic therapy for better long-term tumor control in selected patients.

Right atrial mass with attachment to the atrial septum caused by metastatic renal cell carcinoma

1995 ◽  
Vol 130 (5) ◽  
pp. 1126-1127 ◽  
Author(s):  
Chittur A. Sivaram ◽  
Terrance Khastgir ◽  
Sharon L. Saneman ◽  
Ronald C. Elkins
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell ◽  
Atrial Septum ◽  
Right Atrial ◽  
Atrial Mass ◽  
Right Atrial Mass
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