scholarly journals Uloga Swan-Ganz PA katetera u proceni hemodinamskih promena tokom hirurske revaskularizacije miokarda u bolesnika sa oslabljenom funkcijom leve komore

2002 ◽  
Vol 49 (1) ◽  
pp. 27-35 ◽  
Author(s):  
M. Jovic ◽  
Zoran Popovic ◽  
Dusko Nezic ◽  
V. Ilic ◽  
Sinisa Gradinac ◽  
...  
Keyword(s):  
Cardiac Function ◽  
Left Ventricular Function ◽  
Ventricular Function ◽  
Repeated Measures ◽  
Artery Bypass ◽  
Randomized Study ◽  
Oxygen Metabolism ◽  
Left Ventricular ◽  
Group A ◽  
Group B

Coronary artery bypass surgery in patient with bad left ventricular function is a challenge for surgical time. Specially important is monitoring of haemodynamics. We performed this open, prospective, randomized study with the aim to assess haemodynamics and oxygen profile monitoring. 34 pts for coronary surgery (EF < 40%) were divided in two groups. Group A, 17 pts. Received glucose-insulin-potassium (GIK) solution. Group B, 127 pts. Received Ringer solution. Haemodynamic and oxygen metabolism parameters were measured in four time points. I after the induction in anesthesia; II after the operation; III 6 hours post op.; IV 24 hour post op. Data are expressed as mean +/-SD, ANOVA for repeated measures followed by Newman-Keuls testing were used. In both groups were evident deterioration of cardiac function during first 6h as well as VO2 and DO:, more prominent in Group B. Significant recovery and improvement of cardiac function were evident in Group A after 24 h. CI during the time in Group A improves significantly (2.14+/-0.36 v. 3.05+/-0.55; p=0.0002) and difference during the time between groups was p=0,005. LVSWI improved significantly during the time him Group A (AIII vs. AIV) p=0.007. Simultaneously. VO improves significantly in Group A (103+/-21 vs. 164+/-30, p=0.00001) while difference between groups in DO was p=0.037. Importance of oxygen metabolism monitoring for both, left ventricular function and haemodynamics assessment was evident in our study.

scholarly journals Echocardiographic analysis of the left ventricular function in elderly runners

2015 ◽  
Vol 13 (4) ◽  
pp. 499-505
Author(s):  
Anibal Monteiro de Magalhães Neto ◽  
Nathália Maria Resende ◽  
Carlos Kusano Bucalen Ferrari ◽  
Almir Fernando Loureiro Fontes ◽  
Rimmel Amador Gusman Heredia ◽  
...  
Keyword(s):  
Left Ventricular Function ◽  
Ventricular Function ◽  
Color Doppler ◽  
Statistical Significance ◽  
Left Ventricular ◽  
Elderly Subjects ◽  
Elderly Male ◽  
Mean Values ◽  
Group A ◽  
Group B

Introduction: During the aging process, cardiovascular function suffers intense changes. Objective: To perform an echocardiographic evaluation of left ventricular function in elderly male athletes and non-athletes. Methods: Eleven elderly males were separated into two groups: group A, with six non-athletes (61.66 ± 3.20y) and group B, with eight athletes (62.75 ± 3.24y). Two-dimensional and M mode color Doppler echocardiography were used to assess heart rate (HR), stroke volume (SV), diastolic dimension (DD), systolic dimension (SD), end diastolic volume (EDV), end systolic volume (ESV), mass of the left ventricle (M), isovolumetric relaxation time (IRT), and deceleration time (DT). Results: HR was significantly higher in Group A. The mean values of EDV, ESV, and DT were significantly higher in athletes (Group B). IRT and SV values were higher in Group A; and DD, DS and M trended to be higher in Group B, but without any statistical significance. Conclusions: The regular practice of running improved both hemodynamic and structural variables in elderly subjects.

scholarly journals Adverse Cardiovascular Effects of Ketamine Infusion in Patients with Catecholamine-Dependent Heart Failure

1997 ◽  
Vol 25 (3) ◽  
pp. 255-259 ◽  
Author(s):  
G. Christ ◽  
G. Mundigler ◽  
C. Merhaut ◽  
M. Zehetgruber ◽  
C. Kratochwill ◽  
...  
Keyword(s):  
Heart Failure ◽  
Left Ventricular Function ◽  
Ventricular Function ◽  
Cardiovascular Effects ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Impaired Left Ventricular Function ◽  
Midazolam Group ◽  
Group A ◽  
Group B

The longterm effects of ketamine on haemodynamic parameters and exogenous catecholamine requirements were studied in twenty-five critically ill patients with catecholamine-dependent heart failure. Following sedation with midazolam (0.15±0.07 mg.kg–1.h–1) and sufentanil (0.88±0.33 μg.kg–1.h–1), patients with impaired left ventricular function (left ventricular ejection fraction area 30±7%) were randomly assigned to receive ketamine (2.5±0.9 mg.kg–1.h–1) and midazolam (Group A) or remained on sufentanil/midazolam (Group B). Haemodynamic measurements were performed throughout the first 24 hours after randomization. In group A cardiac index decreased by 21% (P=0.01), mean arterial pressure increased by 13% (P=0.01), mean pulmonary artery pressure by 14% (P=0.04), pulmonary capillary wedge pressure by 20% (P=0.03), and systemic vascular resistance index by 38% (P<0.001). No significant cardiovascular effects were observed in Group B. Neither group had significant changes of exogenous catecholamine requirement. In conclusion, ketamine exhibits potential negative cardiovascular effects in patients with catecholamine-dependent heart failure. Therefore, ketamine should not be considered a first line drug for longterm sedation of patients with impaired left ventricular function.

scholarly journals A comparison of left ventricular function in patients undergoing beating heart bypass surgery using mixed versus pure venous conduits

2017 ◽  
Vol 4 (5) ◽  
pp. 1599
Author(s):  
Tarun Chaudhary ◽  
Hemant Kumar Nautiyal ◽  
Aratatran Nahak ◽  
Shantanu Sahu
Keyword(s):  
Coronary Artery ◽  
Left Ventricular Function ◽  
Ventricular Function ◽  
Bypass Surgery ◽  
Internal Mammary Artery ◽  
Left Ventricular ◽  
Beating Heart ◽  
Internal Mammary ◽  
Group A ◽  
Group B

Background: The pathophysiology of coronary artery disease was established in 1876 by Adam Hammer when he postulated that angina is caused by interruption of coronary blood supply and that myocardial infarction occurred after the occlusion of at least one coronary artery. Aims of the study were to compare the left ventricular function in patients who have undergone beating heart bypass surgery using mixed (internal mammary artery and venous conduits) versus pure Venous conduits, and to compare the incidence of postoperative complications.Methods: It was an observational, analytical study. All patients admitted with triple vessel disease requiring CABG (n=50), with ejection fraction >30%, were subjected to either left internal mammary artery and venous conduits (group A, n=25) or only venous conduits (group B, n=25). Patient who had undergone prior surgical myocardial revascularization, preexisting valvular disease, any evidence of raised pulmonary arterial pressure more than 40/15 mmHg, operated using cardiopulmonary bypass machine, pre-operative use of Intra-Aortic Balloon Pump, any history of neurological dysfunction/Transient ischemic attack, left atrium size more than 5.5 cm were excluded from the studyResults: Improvement in left ventricular function after coronary artery bypass grafting was objectively demonstrated in both the groups. There was a statistically significant increase in mean LVEF in group B (56.16±4.13) compared to group A (51.96±5.30) at 3 months of follow up (p=0.009). The most common complication in both the groups were atrial fibrillation group A=36% (n=9), group= B 16 % (n=4), renal failure group A=12% and group B=8% and sternal wound infection. The post-operative bleeding (Drain output) in first 24 hours was similar in both the groups, 295.56 ml in group A and 265.20ml in group B (p=) with similar hospital stay (group A=9days, group B=8.5days).Conclusions: Patients with venous conduits have better postoperative LVEF as compared to Mixed conduit with similar rate of post-operative complications.

scholarly journals Environmentally persistent free radicals decrease cardiac function and increase pulmonary artery pressure

2012 ◽  
Vol 303 (9) ◽  
pp. H1135-H1142 ◽  
Author(s):  
Sarah Mahne ◽  
Gin C. Chuang ◽  
Edward Pankey ◽  
Lucy Kiruri ◽  
Philip J. Kadowitz ◽  
...  
Keyword(s):  
Free Radicals ◽  
Left Ventricle ◽  
Cardiac Function ◽  
Left Ventricular Function ◽  
Ventricular Function ◽  
Diastolic Pressure ◽  
Silica Particles ◽  
Left Ventricular ◽  
Heme Oxygenase 1 ◽  
Stroke Work

Epidemiological studies have consistently linked inhalation of particulate matter (PM) to increased cardiac morbidity and mortality, especially in at risk populations. However, few studies have examined the effect of PM on baseline cardiac function in otherwise healthy individuals. In addition, airborne PM contain environmentally persistent free radicals (EPFR) capable of redox cycling in biological systems. The purpose of this study was to determine whether nose-only inhalation of EPFRs (20 min/day for 7 days) could decrease baseline left ventricular function in healthy male Sprague-Dawley rats. The model EPFR tested was 1,2-dichlorobenzene chemisorbed to 0.2-μm-diameter silica/CuO particles at 230°C (DCB230). Inhalation of vehicle or silica particles served as controls. Twenty-four hours after the last exposure, rats were anesthetized (isoflurane) and ventilated (3 l/min), and left ventricular function was assessed using pressure-volume catheters. Compared with controls, inhalation of DCB230 significantly decreased baseline stroke volume, cardiac output, and stroke work. End-diastolic volume and end-diastolic pressure were also significantly reduced; however, ventricular contractility and relaxation were not changed. DCB230 also significantly increased pulmonary arterial pressure and produced hyperplasia in small pulmonary arteries. Plasma levels of C-reactive protein were significantly increased by exposure to DCB230, as were levels of heme oxygenase-1 and SOD2 in the left ventricle. Together, these data show that inhalation of EPFRs, but not silica particles, decreases baseline cardiac function in healthy rats by decreasing cardiac filling, secondary to increased pulmonary resistance. These EPFRs also produced systemic inflammation and increased oxidative stress markers in the left ventricle.

scholarly journals Outcome of CABG with or without Coronary Endarterectomy in Bangladesh: A Retrospective Cohort Study

2018 ◽  
Vol 32 (2) ◽  
pp. 77-84
Author(s):  
Redoy Ranjan ◽  
Dipannita Adhikary ◽  
Heemel Saha ◽  
Sabita Mandal ◽  
Sanjoy Kumar Saha ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Renal Impairment ◽  
Left Ventricular Function ◽  
Ventricular Function ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Left Ventricular ◽  
Coronary Endarterectomy ◽  
Surgical Revascularization ◽  
Poor Left Ventricular Function

Objective: In this review, we assess the outcome of surgical revascularization technique, coronary artery bypass grafting (CABG) with or without coronary endarterectomy (CE) for patients with diffuse coronary artery disease in a single surgeon’s practice.Methods: We retrospectively reviewed 2189 patients who experienced OPCABG with or without CE between January 2009 and December 2016. The following variables were compared in this study- Intubation time, ICU stay, Postoperative MI, Arrhythmia, renal impairment, stroke and ICU mortality.Results: Of 2189 patients, 1000 patients required coronary endarterectomy in addition to OPCABG. Initially, there was a higher mortality rate and incidence of postoperative blood transfusion in the group of patients who had CE in addition to CABG, with no significant difference in other outcomes. But postoperative use of Heparin, Warfarin and Double antiplatelet agent was associated with decreased mortality significantly in our study. In comparison to other group, the patients in the combined CE with CABG group had a higher incidence of male sex, past MI, and poor left ventricular function. However,emergency CABG, renal impairment, poor left ventricular function, and also peripheral vascular disease were associated with higher mortality in both group of the patients; CE was not a predictor of postoperative mortality.Conclusions: Total surgical revascularization is attainable and accomplishes, when Coronary endarterectomy is performed in addition to Off-pump coronary artery bypass graft in patients when there is no other choice for satisfactory revascularization.Bangladesh Heart Journal 2017; 32(2) : 77-84

Effects of Coronary-Artery Bypass on Global and Regional Left Ventricular Function during Exercise

1978 ◽  
Vol 298 (26) ◽  
pp. 1434-1439 ◽  
Author(s):  
Kenneth M. Kent ◽  
Jeffry S. Borer ◽  
M. V. Green ◽  
Stephen L. Bacharach ◽  
C. L. McIntosh ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Left Ventricular Function ◽  
Ventricular Function ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Left Ventricular ◽  
Regional Left Ventricular Function
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