scholarly journals Assignment for genes encoding the terminal complement components to porcine chromosome

2014 ◽  
Vol 30 (3) ◽  
pp. 407-414
Author(s):  
Khoa Anh ◽  
K. Wimmers
Keyword(s):  
Radiation Hybrid ◽  
Physical Map ◽  
Radiation Hybrid Panel ◽  
University Of Minnesota ◽  
Porcine Genome ◽  
Porcine Chromosome ◽  
Complement Components ◽  
Genes Encoding ◽  
Terminal Complement ◽  
Genome Projects

One of the major goals of the porcine genome projects is building a physical map. To assign the porcine genes encoding the complement components C6, C7, C8 and C9 to porcine chromosomes, we used a porcine 7000Rad Radiation Hybrid panel (IMpRH) containing 118 clones provided by INRA-University of Minnesota. It resulted in assignment of the porcine C6, C7 and C9 genes to chromosome 16q1.4, the porcine C8A and C8B genes to chromosome 6q3.1-q3.5 as well as the porcine C8G gene lonely to chromosome 1q2.13.

scholarly journals Assignment of three novel genes to porcine chromosome 13 by a radiation hybrid panel

2004 ◽  
Vol 108 (4) ◽  
pp. 363J-363J ◽  
Author(s):  
H. Wang ◽  
Z.M. Zhu ◽  
M. Yerle ◽  
X. Wu ◽  
H.L. Wang ◽  
...  
Keyword(s):  
Radiation Hybrid ◽  
Radiation Hybrid Panel ◽  
Porcine Chromosome ◽  
Novel Genes ◽  
Chromosome 13

scholarly journals A physical map of the human regulator of complement activation gene cluster linking the complement genes CR1, CR2, DAF, and C4BP.

1988 ◽  
Vol 167 (2) ◽  
pp. 664-669 ◽  
Author(s):  
J Rey-Campos ◽  
P Rubinstein ◽  
S Rodriguez de Cordoba
Keyword(s):  
Gene Cluster ◽  
Complement Activation ◽  
Gel Electrophoresis ◽  
Physical Map ◽  
Pulsed Field Gel Electrophoresis ◽  
Complement Components ◽  
Pulsed Field ◽  
Human Genes ◽  
Tight Linkage ◽  
Genes Encoding

We report the organization of the human genes encoding the complement components C4-binding protein (C4BP), C3b/C4b receptor (CR1), decay accelerating factor (DAF), and C3dg receptor (CR2) within the regulator of complement activation (RCA) gene cluster. Using pulsed field gel electrophoresis analysis these genes have been physically linked and aligned as CR1-CR2-DAF-C4BP in an 800-kb DNA segment. The very tight linkage between the CR1 and the C4BP loci, contrasted with the relative long DNA distance between these genes, suggests the existence of mechanisms interfering with recombination within the RCA gene cluster.

scholarly journals Assignment of phosphatidylinositol glycan, class K (PIGK) gene to porcine chromosome 6q32 by somatic cell and radiation hybrid panel mapping

2004 ◽  
Vol 108 (4) ◽  
pp. 363G-363G
Author(s):  
E.W. Park ◽  
J.H. Kim ◽  
H.T. Lim ◽  
B.Y. Seo ◽  
I.C. Cho ◽  
...  
Keyword(s):  
Somatic Cell ◽  
Radiation Hybrid ◽  
Radiation Hybrid Panel ◽  
Porcine Chromosome
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