scholarly journals Transition metal complexes with a new tridentate ligand, 5-[6-(5-mercapto- 1,3,4-oxadiazol-2-yl)pyridin-2-yl]-1,3,4-oxadiazole-2-thiol

2007 ◽  
Vol 72 (4) ◽  
pp. 357-366 ◽  
Author(s):  
Kalagouda Gudasi ◽  
Manjula Patil ◽  
Ramesh Vadavi ◽  
Rashmi Shenoy ◽  
Siddappa Patil
Keyword(s):  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Thermal Studies ◽  
Tridentate Ligand ◽  
Spectral Studies ◽  
1H And 13C Nmr ◽  
Pyridine Nitrogen ◽  
Elemental Analyses ◽  
Thiol Form

A new ligand 5-[6-(5-mercapto-1,3,4-oxadiazol-2-yl)pyridin-2-yl]-1,3,4-oxadiazole- 2-thiol (L) and its Mn(II), Co(II), Ni(II), Cu(II), and Zn(II) complexes were synthesized. The authenticity of the ligand and its transition metal complexes were established by elemental analyses, conductance and magnetic susceptibility measurements, as well as spectroscopic (IR, 1H- and 13C-NMR, electronic, mass, ESR) and thermal studies. The IR and 1H-NMR spectral studies revealed the existence of the ligand in the thiol form in the solid state, whereas in the thione form in the dissolved state. The magnetic and electronic spectral studies suggest an octahedral geometry for all the complexes. The ligand acts as a tridentate ligand coordinating through the pyridine nitrogen and the nitrogen atoms (N-3' and N-3'') of the two oxadiazole rings. Antimicrobial screening of the ligand and its metal complexes were determined against the bacteria Escherichia coli and Bacillus cirroflagellosus, as well as against the fungi, Aspergillus niger and Candida albicans. .

scholarly journals New Ternary Transition Metal Complexes of 2-{[(2-aminophenyl)imino] methyl}Phenol and Metformin: Synthesis, Characterization and Antimicrobial Activity

2011 ◽  
Vol 8 (1) ◽  
pp. 361-367 ◽  
Author(s):  
S. S. Sharma ◽  
J. V. Ramani ◽  
D. P. Dalwadi ◽  
J. J. Bhalodia ◽  
N. K. Patel ◽  
...  
Keyword(s):  
Schiff Base ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Thermal Studies ◽  
Bidentate Ligand ◽  
Octahedral Geometry ◽  
Tridentate Ligand ◽  
Spectral Studies ◽  
Elemental Analyses

Complexes of Co(II), Ni(II) and Cu(II) were synthesized from Schiff base 2-{[(2-aminophenyl)imino]methyl}phenol and metformin. The authenticity of the transition metal complexes were characterized by elemental analyses, conductance and magnetic susceptibility measurements, as well as spectroscopic (IR, electronic) and thermal studies. IR spectral studies revealed the existence of the ligands in the amine form in the solid state. The magnetic and electronic spectral studies suggest an octahedral geometry for all the complexes. The metformin acts as a bidentate ligand and Schiff base ofo-phynelendiamine and salicylaldehyde acts as a tridentate ligand. Antimicrobial screening of the Schiff base, metformin and transition metal complexes were determined against the bacteriaEscherichia coliandBacillus megaterium.

scholarly journals Synthesis, Characterizations and Antimicrobial Activity of Metal Complexes of 2-(2-Furanylmethylaminocarbonyl)benzoic Acid

2011 ◽  
Vol 8 (1) ◽  
pp. 443-448 ◽  
Author(s):  
R. H. Patel ◽  
B. L. Hiran
Keyword(s):  
Antimicrobial Activity ◽  
Antifungal Activity ◽  
Transition Metal ◽  
Benzoic Acid ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Elemental Analysis ◽  
Magnetic Moments ◽  
Thermal Studies ◽  
Spectral Studies

The ligand, 2-(2-furanylmethylaminocarbonyl)benzoic acid (FMBA) and it’s transition metal complexes have been synthesized and characterized by elemental analysis, spectral studies, magnetic moments and thermal studies. The antifungal activity of all the samples was monitored against common fungi.

scholarly journals Synthesis and Characterization of a New Bidentate Ligand 5-Substituted-(2-methyl-5-nitro-1-imidazomethyl)-1,3,4-oxadiazole-2-thione and its Metal Complexes of Ag(I), Cu(II) and Zn(II)

2011 ◽  
Vol 8 (s1) ◽  
pp. S127-S136
Author(s):  
Shabbir A. A. Kazi
Keyword(s):  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Thermal Studies ◽  
Bidentate Ligand ◽  
Octahedral Geometry ◽  
Spectral Studies ◽  
Ligand Molecule ◽  
H Nmr ◽  
Elemental Analyses

A new ligand (2-methyl-5-nitro-1-imidazomethyl)-1,3,4-oxadiazole-2-thione (L) and its Ag(I),Cu(II) and Zn(II) complexes were synthesized. The authenticity of the ligand and its transition metal complexes were established by elemental analyses, conductance and magnetic susceptibility measurements, as well as spectroscopic (IR,1H NMR, electronic, mass and ESR) and thermal studies. The IR spectral studies revealed the existence thiol-thione tautamerism in the ligand molecule. The magnetic and electronic spectral studies suggest an octahedral geometry for Cu(II) and Zn(II) complexes. The ligand acts as a bidentate coordinating through the N-3 nitrogen and the exocyclic sulfur atoms of oxadiazole rings. Antimicrobial screening of the ligand and its metal complexes were determined against the bacteriaEscherichia coliandSalmonella paratyphiA.

scholarly journals Designing, synthesis and spectral characterization of Schiff base transition metal complexes: DNA cleavage and antimicrobial activity studies

2008 ◽  
Vol 73 (11) ◽  
pp. 1063-1071 ◽  
Author(s):  
N. Raman ◽  
Syed Ali ◽  
Dhaveethu Raja
Keyword(s):  
Magnetic Susceptibility ◽  
Schiff Base ◽  
Transition Metal ◽  
Metal Complexes ◽  
Spectral Data ◽  
Transition Metal Complexes ◽  
Metal Ion ◽  
Spectral Studies ◽  
Central Metal ◽  
Elemental Analyses

A new series of transition metal complexes of Cu(II), Ni(II), Co(II) and Zn(II) have been designed and synthesized using a Schiff base (L) derived from 4-aminoantipyrine, benzaldehyde and o-phenylenediamine. The structural features were derived from their elemental analyses, magnetic susceptibility and molar conductivity, as well as from mass, IR, UV-Vis, 1H-NMR and ESR spectral studies. The FAB mass spectral data and elemental analyses showed that the complexes had a composition of the ML type. The UV-Vis and ESR spectral data of the complexes suggested a square-planar geometry around the central metal ion. The magnetic susceptibility values of the complexes indicated that they were monomeric in nature. Antimicrobial screening tests were also performed against four bacteria, viz. Salmonella typhi, Staphylococcus aureus, Escherichia coli, and Bacillus subtilis and three fungi, viz. Aspergillus niger, Aspergillus flavus and Rhizoctonia bataicola. These data gave good results in the presence of metal ion in the ligand system. The nuclease activity of the above metal complexes shows that only the copper complex cleaves CT DNA in the presence of an oxidant.

scholarly journals Synthesis, Characterization and Chelating Properties of Benzoxazolidin-2-one/ 4 - aminosalicylic Acid Clubbed Molecule Part – I

2006 ◽  
Vol 3 (4) ◽  
pp. 319-326 ◽  
Author(s):  
G. J. Patel ◽  
M. V. Hathi ◽  
S. V. Patel
Keyword(s):  
Transition Metal ◽  
Metal Complexes ◽  
Microbial Activity ◽  
Transition Metal Complexes ◽  
Magnetic Moment ◽  
Conductivity Measurement ◽  
Molar Conductivity ◽  
Spectral Studies ◽  
Aminosalicylic Acid ◽  
Elemental Analyses

Aminomethylation of benzoxazolidin-2–one was carried out by treating benzoxazolidin-2–one with formaldehyde and 4 – aminosalicylic acid. The resultant compound was designated as 3–(4-carboxy–3 - hydroxyphenyl aminomethyl) benzoxazolidin-2-one (CHPA-BOX) The transition metal complexes of Cu2+Co2+Ni2+, Mn2+, Zn2+, UO2+and Fe3+of CHPA-BOX have been prepared. Elemental analyses, spectral studies, magnetic moment determination, molar conductivity measurement and microbial activity of CHPA-BOX and its metal complexes were carried out.

scholarly journals Synthesis, Characterization and Chelating Properties of Benzimidazole-Salicylic Acid Combined Molecule

2009 ◽  
Vol 6 (1) ◽  
pp. 281-288 ◽  
Author(s):  
Kamlesh V. Patel ◽  
Arun Singh
Keyword(s):  
Salicylic Acid ◽  
Transition Metal ◽  
Transition Metal Complexes ◽  
Magnetic Moment ◽  
Mannich Reaction ◽  
Conductivity Measurement ◽  
Molar Conductivity ◽  
Spectral Studies ◽  
Aminosalicylic Acid ◽  
Elemental Analyses

Aminomethylation (i.e.Mannich reaction) of benzimidazole was carried out by treating benzimidalzole with formaldehyde and 4-aminosalicylic acid. The resultant compound was designated as 1-(4-carboxy-3-hydroxyphenyl aminomethyl) benzimidazole (BI-SA). The transition metal complexes of Cu2+, Co2+, Ni2+, Mn2+, Zn2+and Fe3+of BI-SA have been prepared and characterized by elemental analyses, spectral studies, magnetic moment determination, molar conductivity measurement and microbicidal activity.

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