scholarly journals New Ternary Transition Metal Complexes of 2-{[(2-aminophenyl)imino] methyl}Phenol and Metformin: Synthesis, Characterization and Antimicrobial Activity

2011 ◽  
Vol 8 (1) ◽  
pp. 361-367 ◽  
Author(s):  
S. S. Sharma ◽  
J. V. Ramani ◽  
D. P. Dalwadi ◽  
J. J. Bhalodia ◽  
N. K. Patel ◽  
...  
Keyword(s):  
Schiff Base ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Thermal Studies ◽  
Bidentate Ligand ◽  
Octahedral Geometry ◽  
Tridentate Ligand ◽  
Spectral Studies ◽  
Elemental Analyses

Complexes of Co(II), Ni(II) and Cu(II) were synthesized from Schiff base 2-{[(2-aminophenyl)imino]methyl}phenol and metformin. The authenticity of the transition metal complexes were characterized by elemental analyses, conductance and magnetic susceptibility measurements, as well as spectroscopic (IR, electronic) and thermal studies. IR spectral studies revealed the existence of the ligands in the amine form in the solid state. The magnetic and electronic spectral studies suggest an octahedral geometry for all the complexes. The metformin acts as a bidentate ligand and Schiff base ofo-phynelendiamine and salicylaldehyde acts as a tridentate ligand. Antimicrobial screening of the Schiff base, metformin and transition metal complexes were determined against the bacteriaEscherichia coliandBacillus megaterium.

scholarly journals Transition metal complexes with a new tridentate ligand, 5-[6-(5-mercapto- 1,3,4-oxadiazol-2-yl)pyridin-2-yl]-1,3,4-oxadiazole-2-thiol

2007 ◽  
Vol 72 (4) ◽  
pp. 357-366 ◽  
Author(s):  
Kalagouda Gudasi ◽  
Manjula Patil ◽  
Ramesh Vadavi ◽  
Rashmi Shenoy ◽  
Siddappa Patil
Keyword(s):  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Thermal Studies ◽  
Tridentate Ligand ◽  
Spectral Studies ◽  
1H And 13C Nmr ◽  
Pyridine Nitrogen ◽  
Elemental Analyses ◽  
Thiol Form

A new ligand 5-[6-(5-mercapto-1,3,4-oxadiazol-2-yl)pyridin-2-yl]-1,3,4-oxadiazole- 2-thiol (L) and its Mn(II), Co(II), Ni(II), Cu(II), and Zn(II) complexes were synthesized. The authenticity of the ligand and its transition metal complexes were established by elemental analyses, conductance and magnetic susceptibility measurements, as well as spectroscopic (IR, 1H- and 13C-NMR, electronic, mass, ESR) and thermal studies. The IR and 1H-NMR spectral studies revealed the existence of the ligand in the thiol form in the solid state, whereas in the thione form in the dissolved state. The magnetic and electronic spectral studies suggest an octahedral geometry for all the complexes. The ligand acts as a tridentate ligand coordinating through the pyridine nitrogen and the nitrogen atoms (N-3' and N-3'') of the two oxadiazole rings. Antimicrobial screening of the ligand and its metal complexes were determined against the bacteria Escherichia coli and Bacillus cirroflagellosus, as well as against the fungi, Aspergillus niger and Candida albicans. .

scholarly journals Synthesis and Characterization of a New Bidentate Ligand 5-Substituted-(2-methyl-5-nitro-1-imidazomethyl)-1,3,4-oxadiazole-2-thione and its Metal Complexes of Ag(I), Cu(II) and Zn(II)

2011 ◽  
Vol 8 (s1) ◽  
pp. S127-S136
Author(s):  
Shabbir A. A. Kazi
Keyword(s):  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Thermal Studies ◽  
Bidentate Ligand ◽  
Octahedral Geometry ◽  
Spectral Studies ◽  
Ligand Molecule ◽  
H Nmr ◽  
Elemental Analyses

A new ligand (2-methyl-5-nitro-1-imidazomethyl)-1,3,4-oxadiazole-2-thione (L) and its Ag(I),Cu(II) and Zn(II) complexes were synthesized. The authenticity of the ligand and its transition metal complexes were established by elemental analyses, conductance and magnetic susceptibility measurements, as well as spectroscopic (IR,1H NMR, electronic, mass and ESR) and thermal studies. The IR spectral studies revealed the existence thiol-thione tautamerism in the ligand molecule. The magnetic and electronic spectral studies suggest an octahedral geometry for Cu(II) and Zn(II) complexes. The ligand acts as a bidentate coordinating through the N-3 nitrogen and the exocyclic sulfur atoms of oxadiazole rings. Antimicrobial screening of the ligand and its metal complexes were determined against the bacteriaEscherichia coliandSalmonella paratyphiA.

scholarly journals Designing, synthesis and spectral characterization of Schiff base transition metal complexes: DNA cleavage and antimicrobial activity studies

2008 ◽  
Vol 73 (11) ◽  
pp. 1063-1071 ◽  
Author(s):  
N. Raman ◽  
Syed Ali ◽  
Dhaveethu Raja
Keyword(s):  
Magnetic Susceptibility ◽  
Schiff Base ◽  
Transition Metal ◽  
Metal Complexes ◽  
Spectral Data ◽  
Transition Metal Complexes ◽  
Metal Ion ◽  
Spectral Studies ◽  
Central Metal ◽  
Elemental Analyses

A new series of transition metal complexes of Cu(II), Ni(II), Co(II) and Zn(II) have been designed and synthesized using a Schiff base (L) derived from 4-aminoantipyrine, benzaldehyde and o-phenylenediamine. The structural features were derived from their elemental analyses, magnetic susceptibility and molar conductivity, as well as from mass, IR, UV-Vis, 1H-NMR and ESR spectral studies. The FAB mass spectral data and elemental analyses showed that the complexes had a composition of the ML type. The UV-Vis and ESR spectral data of the complexes suggested a square-planar geometry around the central metal ion. The magnetic susceptibility values of the complexes indicated that they were monomeric in nature. Antimicrobial screening tests were also performed against four bacteria, viz. Salmonella typhi, Staphylococcus aureus, Escherichia coli, and Bacillus subtilis and three fungi, viz. Aspergillus niger, Aspergillus flavus and Rhizoctonia bataicola. These data gave good results in the presence of metal ion in the ligand system. The nuclease activity of the above metal complexes shows that only the copper complex cleaves CT DNA in the presence of an oxidant.

scholarly journals Synthesis and Spectral Studies of 4,4′-(Hydrazine-1,2-diylidenedimethylylidene)-bis-(2- methoxyphenol) and Its Transition Metal Complexes with Promising Biological Activities

2020 ◽  
Vol 32 (7) ◽  
pp. 1768-1772
Author(s):  
Anita Rani ◽  
Manoj Kumar ◽  
Hardeep Singh Tuli ◽  
Zahoor Abbas ◽  
Vinit Prakash
Keyword(s):  
Schiff Base ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Schiff Base Ligand ◽  
Biological Activities ◽  
Condensation Reaction ◽  
Analytical Techniques ◽  
Spectral Studies

The study describes the synthesis, characterization and biological activity of a novel Schiff base ligand and its transition metal complexes. The Schiff base ligand was obtained by a condensation reaction between 4-hydroxy-3-methoxybenzaldehyde (p-vanillin) and hydrazine hydrate using ethanol as solvent. A new series of Ni(II) and Fe(III) complexes were also derived by reaction of prepared Schiff base ligand with NiCl2 and FeCl3. Both the ligand and its metal complexes were characterized by solubility, melting point and elemental analysis. These compounds were further identified by analytical techniques, FTIR, NMR and mass spectrometry. The ligand and its transition metal complexes were also subjected to in vitro biological activities i.e. antimicrobial, antiangiogenic and DNA photo cleavage. For antimicrobial activity compounds were tested against two strains of bacteria and two strains of fungi. Different concentrations of prepared compounds were treated with fertilized chicken eggs and plasmid DNA to find out antiangiogenic and DNA photocleavage activity, respectively.

scholarly journals 1H NMR, Diffused Reflectance, Thermal Studies, ESR and Anti Microbial Activities of Schiff Base Derived from 5-Nitro Salicylaldehyde and p-Anisidine

2015 ◽  
Vol 48 ◽  
pp. 14-26
Author(s):  
Paresh S. More ◽  
Bipin H. Mehta
Keyword(s):  
Schiff Base ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Esr Spectroscopy ◽  
Thermal Studies ◽  
Microbial Activities ◽  
Tetrahedral Structure ◽  
H Nmr ◽  
Square Planar

Transition metal complexes of the type ML1 [Where M= Co(II),Ni(II),Cu(II) and Zn(II), L= Schiff base of 5 nitro-salicylaldehyde and p-anisidine were characterized by using 1H NMR, TGA, Diffused reflectance and ESR spectroscopy. On the basis of above studies Co(II), Ni(II) shows tetrahedral structure, Cu(II) and Zn(II) shows square planar structure.

scholarly journals Synthesis, Characterization and Biological Evaluation of Schiff Base Transition Metal Complexes Derived from 4-Nitrobenzene-1,2-diamine and 5-Chloroisatin

2020 ◽  
Vol 32 (9) ◽  
pp. 2324-2328
Author(s):  
NETRA PAL SINGH ◽  
KAUSHAL KUMAR ◽  
GAJENDRA KUMAR ◽  
ANUROOP KUMAR
Keyword(s):  
Schiff Base ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Magnetic Moments ◽  
Biological Evaluation ◽  
Molar Conductance ◽  
Spectral Studies ◽  
Mass Spectral ◽  
Bacteria And Fungi

A series of transition metal complexes of the type [MLX2], where M = Mn(II), Fe(II), Co(II), Ni(II), X = Cl–/CH3COO– and L = Schiff base derived from 4-nitrobenzene-1,2-diamine and 5-chloroisatin have been synthesized and characterized by elemental analysis, molar conductance, IR, UV-visible, magnetic moments measurement, 1H & 13C NMR and mass spectral studies. On the basis of physico-chemical studies and spectral evaluation, an octahedral geometry have been proposed for all metal(II) complexes. The antimicrobial activity of ligand and its metal complexes have been additionally screened against bacteria and fungi. Metal(II) complexes show good activity as compared to ligand towards studied microorganisms and also metal complexes checked for their catalytic properties for benzoylation of phenol.

scholarly journals Synthesis, Characterizations and Antimicrobial Activity of Metal Complexes of 2-(2-Furanylmethylaminocarbonyl)benzoic Acid

2011 ◽  
Vol 8 (1) ◽  
pp. 443-448 ◽  
Author(s):  
R. H. Patel ◽  
B. L. Hiran
Keyword(s):  
Antimicrobial Activity ◽  
Antifungal Activity ◽  
Transition Metal ◽  
Benzoic Acid ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Elemental Analysis ◽  
Magnetic Moments ◽  
Thermal Studies ◽  
Spectral Studies

The ligand, 2-(2-furanylmethylaminocarbonyl)benzoic acid (FMBA) and it’s transition metal complexes have been synthesized and characterized by elemental analysis, spectral studies, magnetic moments and thermal studies. The antifungal activity of all the samples was monitored against common fungi.

scholarly journals Synthesis and characterization of bioactive binuclear transition metal complexes of Schiff base ligand derived from 4-amino-pyrimidine-2-one, diacetyl and glycine

2014 ◽  
Vol 79 (4) ◽  
pp. 421-433 ◽  
Author(s):  
Abhay Srivastava ◽  
Netra Singh ◽  
Chandra Shriwastaw
Keyword(s):  
Schiff Base ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Schiff Base Ligand ◽  
Magnetic Moment ◽  
Molar Conductance ◽  
Spectral Studies ◽  
Conductance Measurement ◽  
Amino Pyrimidine

A series of novel binuclear transition metal complexes was synthesized by reaction of a Schiff base ligand (1-Methyl-2-(2-oxo-1,2-dihydro-pyrimidin-4-ylimino)-propylideneamino-acetic acid) (LaH) derived from 4-amino-pyrimidine-2-one, diacetyl, glycine and corresponding chloride salt of Cu(II), Ni(II), Co(II) and Zn(II) metals in 1:1 (metal : ligand) molar ratio. The compounds were characterized by elemental analyses, molar conductance measurement, magnetic moment measurement and various spectral studies viz. IR, UV-visible, 1H-NMR, 13C-NMR, EPR and ESI-MS. Molar conductance measurement data revealed non-electrolytic nature of metal complexes. Electronic absorption spectral data, electronic paramagnetic resonance parameters and magnetic moment values revealed an octahedral geometry for binuclear metal complexes. Cyclic voltammetric study of Ni(II) complex shows a couple of one electron anodic responses near 0.70 V and 1.10 V. In vitro biological activity of Schiff base ligand and binuclear complexes has been checked against bacteria (Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Salmonella typhi) and fungi (Candida albicans and Candida parapsilosis) to assess their antibacterial and antifungal properties.

Synthesis, spectral characterization and some biological studies of transition metal complexes with Schiff base ligand containing N,O and S as donor atoms

2017 ◽  
Vol 13 (9) ◽  
pp. 6513-6519
Author(s):  
Anil Kumar M R ◽  
Shanmukhappa S ◽  
Rangaswamy B E ◽  
Revanasiddappa M
Keyword(s):  
Schiff Base ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Schiff Base Ligand ◽  
Dna Cleavage ◽  
Schiff Base Complexes ◽  
Spectral Studies ◽  
Planar Geometry ◽  
Biological Studies

Transition metal complexes of Cu(II), Co(II), Ni(II), Zn(II), Cd(II) and Mn(II) have been synthesized with the Schiff base ligand 5-Sub-N-(2-mercaptophenyl)salicylideneimine. Elemental analysis of these complexes suggest that these metal ions forms complexes of type ML(H2O)stoichiometry for Cu(II), Co(II), Ni(II), Zn(II), Cd(II) and Mn(II). The ligand behaves as tridentate and forms coordinate bonds through O, S and N atoms. Magnetic susceptibility, IR, UV – Visible, Mass and ESR spectral studies suggest that Cu(II), Ni(II) complexes posses square planar geometry, whereas Co(II), Zn(II), Cd(II) and Mn(II) complexes posses tetrahedral geometry. The complexes were tested for their antimicrobial activity against the bacterial strains Staphylococcus aureus and Bacillus subtilis.The Schiff base metal complexes evaluated for their antifungal activity against the fungi A. niger and C. oxysporum. The DNA cleavage studies of Schiff base complexes werestudied using Calf – Thymus DNA by agarose gel electrophoresis method.

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