scholarly journals Role of hydrosonography in prevention and screening of premalignant and malignant endometrial disease

2006 ◽  
Vol 134 (11-12) ◽  
pp. 516-520
Author(s):  
Milena Zamurovic ◽  
Pavle Srbinovic ◽  
Jovana Petrovic

Introduction: The study emphasizes the significance of hydrosonography in prevention and early diagnostics of endometrial pathology. Objective: To express the significance of hydrosonography in relation to timely detection and treatment of premalignant and malignant endometrial disease. Method: Our study included 104 patients referred to transvaginal sonography, after which hydrosonography was recommended in order to obtain precise visualization of the endometrium because of suspected endometrial pathology. After hydrosonography, dilatation and curettage with endometrial biopsy were performed in all patients. Biopsy specimens were histologically analyzed. Results: The application of contrast sonography described in our research helped diagnose and timely treat as many as 30.8% of patients suffering from premalignant and malignant endometrial disease (23.2% of premalignant and 7.6% of malignant). Discomforts (bleeding and pelvic pain) occurred in 72.1% of patients, out of whom 43.3% had already undergone curettage once or more than once because of the same or similar symptoms, while 27.9% of cases presented for regular control, i.e. they were symptom free. The obtained Results clearly emphasized the significance of application of contrast sonohysterography as a Method for timely detection of endometrial pathology and its adequate treatment. Conclusion: The study shows that application of contrast sonohysterography before exploratory curettage significantly facilitates the use of invasive diagnostics and improves accuracy and validity of the obtained Results, especially in cases of endometrial focal changes; consequently, it is also possible to achieve positive cost - benefit effect.

Author(s):  
Pooja J. Mise ◽  
Sangamesh J. Mise ◽  
Aditya Mise ◽  
Margol Siddappa

Background: Transvaginal sonography (TVS) is a new diagnostic technique used for the evaluation of the female pelvis. The objective of the present study was to study the role of TVS and to assess the diagnostic accuracy in gynecological disorders.Methods: Total number of 100 patients attending OPDs with various complaints was selected by random technique of the study.  All the patients have informed consent and thorough clinical examination including general, systemic and pelvic examination was conducted after taking a detailed history then the patients underwent TVS followed by one of the procedures like fractional curettage, dilatation and curettage and abdominal hysterectomy (with or without conservation of ovaries) or conservative management with regular follow up.Results: The sensitivity of TVS in diagnosing dysfunctional uterine bleeding (DUB) and pelvic inflammatory diseases (PID) was 100% and specificity was 85.1% and 95% respectively. For fibroids and ovarian mass diagnosis, sensitivity was 68.9% and 80.9% respectively and specificity was 100%. Diagnostic accuracy of clinical diagnosis was 70.0% whereas TVS had 94.0% of diagnostic accuracy in diagnosing various gynecological disorders.Conclusions: The final outcome is that TVS examination is an important non-invasive investigation, can be used as important diagnostic method in various gynecological disorders as it has got a high diagnostic accuracy.


2020 ◽  
pp. 1-3
Author(s):  
Bishnu Prasad Das ◽  
Chintumoni Gogoi

Objective- to determine the sonographic findings associated with endometrial hyperplasia (EH+) in perimenopausal women with abnormal uterine bleeding (AUB). Methods- a retrospective study, in which 150 subjects, perimenopausal women with AUB, underwent transvaginal sonography (TVS) and endometrial biopsy. The TVS findings were evaluated with regard to EH+. Result- Biopsy proven EH+ was seen in 18.67% of subjects. EH+ was not found in any patient with TVS showing endometrial thickness < 8 mm. Conclusion- There is a strong association between TVS endometrial thickness and endometrial biopsy findings. The risk of development of endometrial cancer is 29% in patients with complex atypical hyperplasia and 2% in patients with hyperplasia without atypia. Thus TVS should be in the first investigation in the management of AUB. Invasive method like dilatation and curettage (D&C) to be considered in cases with endometrial thickness > or = 8 mm.


2007 ◽  
pp. 70-84 ◽  
Author(s):  
E. Demidova

This article analyzes definitions and the role of hostile takeovers at the Russian and European markets for corporate control. It develops the methodology of assessing the efficiency of anti-takeover defenses adapted to the conditions of the Russian market. The paper uses the cost-benefit analysis, where the costs and benefits of the pre-bid and post-bid defenses are compared.


2003 ◽  
Vol 4 (1) ◽  
pp. 10-19
Author(s):  
Duncanson V

T his article describes a small study aimed at making a purchasing recommendation to the purchasing manager, providing a cost-benefit analysis of the most commonly used brands of non-sterile latex examination gloves. One of the nine makes of glove tested remained consistent with the agreed criteria for assessment and, if introduced as the only option available, would result in a saving of $15,150 per annum on Site A of a recently merged secondary care Trust. Also, the importance of the consultancy role of the clinical nurse specialist in improving practice was demonstrated.


1970 ◽  
Vol 1 (1) ◽  
pp. 13-16 ◽  
Author(s):  
R Baral ◽  
S Pudasaini

Background: Histological characteristics of endometrial biopsy material as assessed by light microscopy remain the diagnostic standard for the clinical diagnosis of endometrial pathology. Management of abnormal uterine bleeding is not complete without tissue diagnosis. The aim of the study was to find out the histopathological pattern of the endometrium in abnormal uterine bleeding. Materials and Methods: Endometrial biopsy specimens received from Jan 2007 to Nov 2010 were studied retrospectively in the Department of Histopathology, Helping Hands Community Hospital, Kathmandu. The specimens were routinely processed and the hematoxyllin and eosin stained slides were studied. Results: A total of 300 specimens were analyzed. In the group of patients less than 40 years of age, 73 (50%) were normal, 34(23%) had abnormal physiologic changes and 13 (9%) had pregnancy related complications and benign changes. In the age group between 40 – 55 years, abnormal physiological changes, benign conditions and normal physiological changes were 45 (32%), 41 (29%) and 37 (26%) respectively. In the age group > 55 years, there were 3(21%) malignant and 3(21%) benign conditions. There were 5(36%) unsatisfactory samples in this age group. Conclusion: It is important to know the histological pattern of the endometrium in abnormal uterine bleeding in different age groups since it will help in the management of the cases. In this study endometrial hyperplasias were seen in 55 cases (18.8%). The importance of studying the histological pattern of endometrium in abnormal uterine bleeding in different age group is to help in correctly managing the cases. Keywords: Endometrium; Simple hyperplasia; Complex hyperplasia; Endometritis; Endometrial Carcinoma. DOI: 10.3126/jpn.v1i1.4443 Journal of Pathology of Nepal (2011) Vol.1, 13-16


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