scholarly journals The effect of intraocular lens material and postoperative therapy on the posterior capsule opacification development after the senile cataract surgery

2020 ◽  
Vol 148 (5-6) ◽  
pp. 333-337
Author(s):  
Dusan Todorovic ◽  
Tatjana Sarenac-Vulovic ◽  
Nenad Petrovic ◽  
Svetlana Jovanovic ◽  
Mirjana Janicijevic-Petrovic ◽  
...  

Introduction/Objective. The most frequent postoperative complication of a successfully performed phacoemulsification cataract surgery is the development of posterior capsule opacification (PCO). It is caused by the proliferation and migration of the remaining residual epithelial cells. The objective of this study was to investigate the influence of two different intraocular lenses and two different anti-inflammatory drugs on the development of PCO in one-year follow-up period. Methods. Investigation included 120 patients (120 eyes), equally divided into four groups. The first two groups included patients who used non-steroid anti-inflammatory drug (NSAID) postoperatively, while the other groups had corticosteroid therapy. The first and third group got hydrophilic intraocular lenses (IOL), the second and fourth group had hydrophobic IOL. Software program EPCO 2000 was used for the analysis of PCO. Student?s t-test, Wilcoxon test, and ANOVA were used for data analysis and p < 0.05 value was accepted as statistically significant. Results. After the first three postoperative months, patients from NSAID groups had mean PCO score 0.25 ?} 0.03, which was statistically significant higher (p = 0.042) comparing to corticosteroid groups. At the end of the investigation, the best result in PCO preventing was seen in the group of patients with hydrophobic IOL and corticosteroid therapy, with the mean PCO score of 0.47 ?} 0.08. Conclusion. This study has revealed that IOL made of acrylic hydrophobic material seemed to be the right choice when choosing intraocular lens to prevent PCO development. On the other hand, NSAID and corticosteroid therapy have showed similar results in preventing postoperative intraocular inflammation. This fact can be very useful in situations when corticosteroids must be used with great caution.

2018 ◽  
Vol 28 (6) ◽  
pp. 639-644 ◽  
Author(s):  
John Koshy ◽  
Nino Hirnschall ◽  
Ashok Kumar V Vyas ◽  
R Narendran ◽  
Alja Crnej ◽  
...  

Purpose: To evaluate the capsular bag performance and posterior capsule opacification development of two intraocular lenses differing in material and design. Methods: This study included patients who were scheduled for cataract surgery and compared a hydrophilic intraocular lens (Super flex® intraocular lens; Rayner Surgical, Worthing, UK) with a hydrophobic intraocular lens (AcrySof® SA60AT; Alcon, Fort Worth, TX, USA). Follow-ups were performed 1 month and 2 years after cataract surgery, including a slit lamp examination and retroillumination images. Results: In total, 80 eyes of 80 patients were recruited. At the 1-month follow-up, 6 of 39 cases had a gap between the posterior lens capsule and intraocular lens (1 case in the hydrophilic intraocular lens group and 5 cases in the hydrophobic intraocular lens group; p = 0.348). Objective and subjective posterior capsule opacification scoring showed no statistically significant difference between both groups (p = 0.123). Conclusion: Both intraocular lens showed a good capsular bag performance and a relatively low posterior capsule opacification development within the first 2 years after surgery.


2018 ◽  
Author(s):  
Shixu Li ◽  
Yiping Hu ◽  
Ran Guo ◽  
Yushuang Shao ◽  
Jiangyue Zhao ◽  
...  

Abstract Background:To evaluate the effects of anterior capsular opening size on deviation from predicted refraction and the effective position of intraocular lens (ELP) in cataract surgery. Methods:Eighty patients (80 eyes) with simple age-related cataracts were treated from May 2018 to September 2018 at the Fourth Affiliated Hospital of China Medical University. The patients were divided into 2 groups : 40 eyes were implanted with the C-loop haptic intraocular lens (AMO Tecnis ZCB00) while the other 40 eyes were implanted with the plate haptic intraocular lens (CT ASPHINA 509M). Follow-up visits were conducted postoperatively at 1 week, 1 month, and 3 months during which patients underwent refraction and data collection after pupil dilation that included anterior segment photography and Scheimpflug imaging by Pentacam. The area, horizontal and vertical diameter of the capsulorrhexis, circularity, decentration, and package were analysed using the image analysis software Image-Pro-Plus 6.0 that evaluated the relationship between the different shapes of capsulorrhexis with deviation from predicted refraction and ELP in cataract surgery. Results: Deviation from predicted refraction and all of the parameters of capsulorrhexis were not correlative in the 509M IOL group, however, in the Tecnis IOL group, while the deviation from predicted refraction and all of the capsulorrhexis parameters were not correlative at 1 week, the deviation from predicted refraction did correlate with capsulorrhexis area,horizontal diameter at 1 month (P=0.029, P=0.048), and the capsulorrhexis area ,vertical diameter at 3 months (P=0.03, P=0.017).The ELP correlated with package in both groups postoperatively (r>0, P<0.05), but there is no other capsulorrhexis parameters correlate with ELP in the 509M IOL group (all P>0.05). For the Tecnis IOL group, the ELP and capsulorrhexis area were correlated at 1 week and 1 month, while the ELP and horizontal diameter, the ELP and vertical diameter were correlated at 1 week , but did not correlate with the other capsulorrhexis parameters in the Tecnis IOL group (all P>0.05). Conclusions: The shape of the capsulorrhexis has an effect on postoperative refractive outcomes and the effective position of intraocular lens in cataract surgery, and plate haptic intraocular lenses have better refractive stability than C-loop haptic intraocular lenses.(ChiCTR-TRC-1800015638)


2004 ◽  
Vol 30 (4) ◽  
pp. 786-789 ◽  
Author(s):  
Lloyd E Bender ◽  
Christoph Nimsgern ◽  
Romina Jose ◽  
Hari Jayaram ◽  
David J Spalton ◽  
...  

RSC Advances ◽  
2015 ◽  
Vol 5 (5) ◽  
pp. 3597-3604 ◽  
Author(s):  
Bailiang Wang ◽  
Quankui Lin ◽  
Tingwei Jin ◽  
Chenghui Shen ◽  
Junmei Tang ◽  
...  

Posterior capsule opacification is one of the complications of cataract surgery caused by the adhesion and reproduction of residual human lens epithelial cells (HLECs) on the posterior capsule.


Sign in / Sign up

Export Citation Format

Share Document