Radiation and Whole Light Effects on Molluscan Nerve Cells in Vitro

1967 ◽  
Vol 31 (3) ◽  
pp. 452 ◽  
Author(s):  
Makoto Sato ◽  
George Austin ◽  
Hideko Yai
Keyword(s):  
Nerve Cells ◽  
Light Effects

scholarly journals Anticancer activity of midostaurin in hormone refractory human prostate cancer DU145 cells

2016 ◽  
Vol 11 (2) ◽  
pp. 378
Author(s):  
Jin-Jun Sun ◽  
Shi-Feng Kan ◽  
Guan-Xing Sun
Keyword(s):  
Prostate Cancer ◽  
Kinase Inhibitor ◽  
Cancer Cell Line ◽  
Prostate Cancer Cell Line ◽  
Nerve Cells ◽  
Human Prostate ◽  
Human Prostate Cancer ◽  
Du145 Cells ◽  
Hormone Refractory

<p class="Abstract">We tried a new method of prostate cancer treatment by inducing<em> in vitro</em> differentiation which resulted in reduction of cancer cells growth. A protein kinase inhibitor, midostaurin's ability to trigger the human prostate cancer cell line, DU145 to segregate into nerve cells was studied. Midostaurin (100 nM) suppressed the growth of DU145 cells but without change in the number of dead cells. Midostaurin started to extend neurites on DU145 cells after 24 hours and differentiated into nerve cells by 72 hours. The microtubule was stabilized by tau protein and its mRNA expression showed time-dependent increase in midostaurin-treated DU145 cells. At the same time, the amount of acetylcholinesterase was also increased. The midostaurin-treated DU145 cells showed 40% less activity than control in the colony forming assay. The results suggests that midostaurin can induce differentiation of DU145 cells into nerve cells.</p><p> </p>

VISNA VIRUS INDUCED FUSION OF NERVE CELLS IN VITRO

1978 ◽  
Vol 37 (5) ◽  
pp. 628
Author(s):  
E. Hooghe-Peters ◽  
M. Dubois-Dalcq ◽  
D. Schmechel
Keyword(s):  
Nerve Cells ◽  
Visna Virus

The preservation of nerve cells in rat neostriatal slices maintained in vitro: A morphological study

1980 ◽  
Vol 197 (2) ◽  
pp. 341-353 ◽  
Author(s):  
Il Jin Bak ◽  
Ulrich Misgeld ◽  
Molly Weiler ◽  
Ellen Morgan
Keyword(s):  
Morphological Study ◽  
Nerve Cells ◽  
Neostriatal Slices

scholarly journals Influence of ketamine on amino acid neurotransmitters secretion by nerve cells in vitro

2016 ◽  
Vol 11 ◽  
pp. S55-S60
Author(s):  
Mingxian Shi ◽  
Rui Chen ◽  
Cen Guo ◽  
Li Gao
Keyword(s):  
Amino Acid ◽  
Glutamic Acid ◽  
Acid Concentration ◽  
Excitatory Amino Acid ◽  
Nerve Cells ◽  
Amino Acid Neurotransmitters ◽  
Different Doses ◽  
Amino Acid Glycine

In order to study the influence of amino acid neurotransmitters secreted by the nerve cells after ketamine treatment, the nerve cells were cultured in vitro to exclude the interference of other factors in vivo and treated with three different doses of ketamine (1, 3 and 5 µg/mL). Then, the concentration of neuronal amino acid neurotransmitters was examined at 0, 15, 30, 45, 60, 90, 120 min after treatment. The trends of each amino acid concentration after ketamine treatment were nearly the same among the different treatment doses. After 15 min of adapting time, ketamine decreased the excitatory amino acid glutamic acid and aspartic acid concentration, and increased the concentration of the inhibitory amino acid glycine. Their concentrations showed a tendency to return approximately to the original level after 120 min. 

scholarly journals STUDIES ON THE PROPAGATION IN VITRO OF POLIOMYELITIS VIRUSES

1952 ◽  
Vol 96 (4) ◽  
pp. 389-400 ◽  
Author(s):  
William F. Scherer ◽  
Jerome T. Syverton
Keyword(s):  
Virus Type ◽  
Testicular Tissue ◽  
Nerve Cells ◽  
Specific Antibodies ◽  
Poliomyelitis Virus ◽  
Explant Cultures ◽  
Pure Cultures ◽  
Primary Explant

Cells like fibroblasts, having no resemblance whatever to nerve cells were obtained in morphologically pure cultures from monkey testicular tissue and were found to support the growth in vitro of poliomyelitis virus, Type 2, Yale-SK strain. Moreover, these cells were destroyed as a result of the multiplication of this virus within them. Similarly, "fibroblasts" propagated in primary explant cultures of testicle were destroyed by poliomyelitis viruses, Types 1 and 2. Type specific antibodies neutralized the pathogenic effect of poliomyelitis virus on monkey testicular fibroblasts.

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