Flower-Enhanced Expression of a Nuclear-Encoded Mitochondrial Respiratory Protein Is Associated with Changes in Mitochondrion Number

1994 ◽  
Vol 6 (3) ◽  
pp. 439
Author(s):  
Jintal Huang ◽  
Friedhelm Struck ◽  
Dale F. Matzinger ◽  
Charles S. Levings
Keyword(s):  
Respiratory Protein ◽  
Enhanced Expression ◽  
Mitochondrial Respiratory

Enhanced expression of TGFβ, collagen, and TIMP-1 genes in esophageal stricture

2001 ◽  
Vol 120 (5) ◽  
pp. A153-A153
Author(s):  
M KLINE ◽  
Z ZANG ◽  
K PATEL ◽  
S FRENCH ◽  
H TSUKAMOTO
Keyword(s):  
Esophageal Stricture ◽  
Enhanced Expression

Anti-Diabetic Activity of a Mineraloid Isolate, in vitro and in Genetically Diabetic Mice

2011 ◽  
Vol 81 (1) ◽  
pp. 34-42 ◽  
Author(s):  
Joel Deneau ◽  
Taufeeq Ahmed ◽  
Roger Blotsky ◽  
Krzysztof Bojanowski
Keyword(s):  
Dna Microarrays ◽  
Human Fibroblasts ◽  
Diabetic Animal ◽  
In Vitro Tests ◽  
Diabetic Mice ◽  
Fossil Material ◽  
Expression Of Genes ◽  
Enhanced Expression ◽  
Genetically Diabetic Mice

Type II diabetes is a metabolic disease mediated through multiple molecular pathways. Here, we report anti-diabetic effect of a standardized isolate from a fossil material - a mineraloid leonardite - in in vitro tests and in genetically diabetic mice. The mineraloid isolate stimulated mitochondrial metabolism in human fibroblasts and this stimulation correlated with enhanced expression of genes coding for mitochondrial proteins such as ATP synthases and ribosomal protein precursors, as measured by DNA microarrays. In the diabetic animal model, consumption of the Totala isolate resulted in decreased weight gain, blood glucose, and glycated hemoglobin. To our best knowledge, this is the first description ever of a fossil material having anti-diabetic activity in pre-clinical models.

Enhanced expression of the transcriptional activators YAP and TAZ in non-secreting pituitary tumours

2018 ◽  
Author(s):  
Paraskevi Xekouki ◽  
Emily Lodge ◽  
Ran Li ◽  
Jorg Flitsch ◽  
Stefan Bornstein ◽  
...  
Keyword(s):  
Transcriptional Activators ◽  
Pituitary Tumours ◽  
Enhanced Expression
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