Total Blindness :

2021 ◽  
pp. 299-309
Keyword(s):  
2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Hiroki Sato ◽  
Ryoko Kyan ◽  
Chinami Kamada ◽  
Mitsunori Kaku ◽  
Shota Sato ◽  
...  

Retina ◽  
1996 ◽  
Vol 16 (5) ◽  
pp. 445-447 ◽  
Author(s):  
JERRY A. SHIELDS ◽  
CAROL L. SHIELDS ◽  
JAMES ELLIS ◽  
PATRICK DEPOTTER

2019 ◽  
Vol 37 (3) ◽  
pp. 227-239
Author(s):  
Errol Ingram ◽  
Pat Dorsett ◽  
Kym Macfarlane

This phenomenological study explored how individual young adults understood their lived experience of acquiring life skills with congenital total blindness (CTB). Four young adults with CTB, and five parents of the young adults, participated in the study. In depth, semi-structured interviews were used to gather information from the research participants. The interviews were analysed using interpretative phenomenological analysis (IPA). Five superordinate themes emerged from the IPA: (1) life skills acquisition as ‘a means to an end’, (2) appraising life skills acquisition, (3) acquiring disability-specific skills, (4) reaching adulthood with life skill gaps, and (5) making sense of independence. The findings revealed that the young adults had reached adulthood with significant gaps in their acquisition of basic life skills. This indicates that more needs to be done, to improve the efficacy and meaning of life skill acquisition programmes provided in childhood and adolescence, to young people living with CTB.


1989 ◽  
Vol 83 (10) ◽  
pp. 500-504
Author(s):  
E. Trief ◽  
R. Duckman ◽  
A.R. Morse ◽  
R.K. Silberman

Retinopathy of prematurity (ROP), formerly called retro-lental fibroplasia (RLF), has increased in the 1980s due to a high incidence of premature, low birthweight infants. Apparently, oxygen administration alone does not account for all these ROP babies. Birth-weight, gestational age, and duration of administration of oxygen are primary contributors to ROP development. The stages of severity range from no visual damage to total blindness. Treatments are either pharmacological or surgical. Vitamin E therapy, photocoagulation procedures, cryotherapy, scleral buckling procedures, and vitrectomy are common treatments, but none is totally successful in ameliorating this condition. The educational problems of children with ROP parallel those of other visually impaired children, with deficits found primarily in exploration, mobility, and language. Referral to early intervention programs can provide a comprehensive structured learning situation and support to the entire family.


2003 ◽  
Vol 27 (3) ◽  
pp. 193-200 ◽  
Author(s):  
Amedeo D’Angiulli ◽  
Stefania Maggi

We studied the development of spontaneous tactile drawing in three 12-year-old children with congenital total blindness and with no previous drawing tuition. In a period of 9 months, from an initial phase in which they were taught to draw tangible straight and curve raised lines, the three blind children went on making spontaneous raised outlines representing edges, surfaces of objects, vantage point, and motion. The corpus of drawings produced by these children shows that several aspects of outline pictures can be implemented through touch. The perceptual principles represented in these drawings are comparable to those commonly found in sighted children. On the one hand, this convergence indicates similarities in the way vision and touch mediate the acquisition and the conceptualisation of spatial information from objects and the environment. On the other hand, it reflects the influence of cross-modal plasticity typically associated with early or congenital blindness. This study suggests that drawing development in general does not depend on learning pictorial conventions. Rather it seems driven by natural generativity based on children’s knowledge of space and perceptual principles.


2020 ◽  
Vol 117 (35) ◽  
pp. 21690-21700 ◽  
Author(s):  
Joel B. Miesfeld ◽  
Noor M. Ghiasvand ◽  
Brennan Marsh-Armstrong ◽  
Nicholas Marsh-Armstrong ◽  
Eric B. Miller ◽  
...  

The retinal ganglion cell (RGC) competence factor ATOH7 is dynamically expressed during retinal histogenesis.ATOH7transcription is controlled by a promoter-adjacent primary enhancer and a remote shadow enhancer (SE). Deletion of theATOH7human SE causes nonsyndromic congenital retinal nonattachment (NCRNA) disease, characterized by optic nerve aplasia and total blindness. We used genome editing to model NCRNA in mice. Deletion of the murine SE reducesAtoh7messenger RNA (mRNA) fivefold but does not recapitulate optic nerve loss; however, SEdel/knockout (KO)transheterozygotes have thin optic nerves. By analyzingAtoh7mRNA and protein levels, RGC development and survival, and chromatin landscape effects, we show that the SE ensures robustAtoh7transcriptional output. Combining SE deletion and KO and wild-type alleles in a genotypic series, we determined the amount ofAtoh7needed to produce a normal complement of adult RGCs, and the secondary consequences of graded reductions inAtoh7dosage. Together, these data reveal the workings of an evolutionary fail-safe, a duplicate enhancer mechanism that is hard-wired in the machinery of vertebrate retinal ganglion cell genesis.


1996 ◽  
Vol 90 (2) ◽  
pp. 125-133
Author(s):  
G.M. Lane

To investigate the crossmodal transfer effects of verbal information to the performance of manual tasks, this study compared the effectiveness of two strategies—manual guidance only and manual guidance plus verbal prompts—with students whose multiple disabilities included total blindness and severe mental retardation. Within the framework of an alternating treatments design, the two strategies were differentially applied to two tasks. The results suggest that prompting methods that require shifting verbal information to the performance of a manual task may interfere with the learning of students with such multiple disabilities.


1956 ◽  
Vol 254 (25) ◽  
pp. 1181-1182 ◽  
Author(s):  
Maxwell L. Gelfand

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