scholarly journals Magnetic Resonance Tracking of Endothelial Progenitor Cells Labeled with Alkyl-Polyethylenimine 2 kDa/Superparamagnetic Iron Oxide in a Mouse Lung Carcinoma Xenograft Model

2014 ◽  
Vol 13 (9) ◽  
pp. 7290.2014.00030 ◽  
Author(s):  
Cong Chen ◽  
Hong Yu ◽  
Rui Xia ◽  
Lei Wang ◽  
Hua Ai ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Magnetic Resonance ◽  
Progenitor Cells ◽  
Endothelial Progenitor Cells ◽  
Lung Carcinoma ◽  
Xenograft Model ◽  
Superparamagnetic Iron Oxide ◽  
Mouse Lung ◽  
Endothelial Progenitor ◽  
Carcinoma Xenograft

scholarly journals Experimental study of endothelial progenitor cells labeled with superparamagnetic iron oxide in vitro

2014 ◽  
Vol 11 (5) ◽  
pp. 3814-3819 ◽  
Author(s):  
MENG-QI WEI ◽  
DI-DI WEN ◽  
XIAO-YING WANG ◽  
YI HUAN ◽  
YONG YANG ◽  
...  
Keyword(s):  
Experimental Study ◽  
Iron Oxide ◽  
Progenitor Cells ◽  
Endothelial Progenitor Cells ◽  
Superparamagnetic Iron Oxide ◽  
Endothelial Progenitor

Study on MR Imaging of Endothelial Progenitor Cells Labeled with the Complex of Super Paramagnetic Iron Oxide and Transfection

2013 ◽  
Vol 683 ◽  
pp. 885-888
Author(s):  
Na Chang ◽  
Jun Zhang ◽  
Jun Shi Zhang
Keyword(s):  
Iron Oxide ◽  
Mr Imaging ◽  
Progenitor Cells ◽  
Endothelial Progenitor Cells ◽  
Mononuclear Cells ◽  
Gradient Centrifugation ◽  
Superparamagnetic Iron Oxide ◽  
Effective Rate ◽  
Endothelial Progenitor ◽  
Ficoll Density Gradient Centrifugation

To explore the characteristics of magnetic resonance（MR）imaging of the rat endothelial progenitor cells（EPCs）labeled with superparamagnetic iron oxide（SPIO）. Total mononuclear cells (MNCs) were isolated from SD rat peripheral blood by ficoll density gradient centrifugation, and then the cells were plated on fibronectin-coated culture dishes. Attached cells were collected after 7 days cultured. EPCs were indentified by the laser confocal microscope and were counted in the inverted fluorescence microscope. EPCs were incubated with Fe2O3-arginine for 24 h, and the cells underwent MR imaging with three sequences (T1 WI, T2 WI, T2*WI). The results showed that the effective rate of labeled EPCs was 96%, and the survival rate of cells was 95%. The signal intensity on MRI was significantly decreased in labeled EPCs compared with unlabeled cells. EPCs labeled with SPIO can be sensitively displayed by the MR imaging.

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