A Case of Giant Phyllodes Tumor of the Breast

2013 ◽  
Vol 75 (6) ◽  
pp. 514-517
Author(s):  
Yuka NAKAMURA ◽  
Makoto ICHIMIYA ◽  
Kei NEMOTO ◽  
Yoshitaka NAKAMURA ◽  
Michiya YAMAGUCHI ◽  
...  
Keyword(s):  
Phyllodes Tumor

Giant phyllodes tumor of the breast

2019 ◽  
Vol 1 (23) ◽  
pp. 20
Author(s):  
Anca Zgură ◽  
Laurenţia Galeş ◽  
Elvira Brătilă ◽  
Rodica ANGHEL
Keyword(s):  
Phyllodes Tumor

scholarly journals Bilateral Phyllodes Giant Tumor. A Case Report Analyzed by Array-CGH

Diagnostics ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 825
Author(s):  
Francesco Fortarezza ◽  
Federica Pezzuto ◽  
Gerardo Cazzato ◽  
Clelia Punzo ◽  
Antonio d’Amati ◽  
...  
Keyword(s):  
Array Cgh ◽  
Phyllodes Tumor ◽  
Molecular Classification ◽  
Left Breast ◽  
Comparative Genomic ◽  
Fish Analysis ◽  
Molecular Tests ◽  
Giant Tumor ◽  
Metastatic Risk ◽  
The Right

The breast phyllodes tumor is a biphasic tumor that accounts for less than of 1% of all breast neoplasms. It is classified as benign, borderline, or malignant, and can mimic benign masses. Some recurrent alterations have been identified. However, a precise molecular classification of these tumors has not yet been established. Herein, we describe a case of a 43-year-old woman that was admitted to the emergency room for a significant bleeding from the breast skin. A voluminous ulcerative mass of the left breast and multiple nodules with micro-calcifications on the right side were detected at a physical examination. A left total mastectomy and a nodulectomy of the right breast was performed. The histological diagnosis of the surgical specimens reported a bilateral giant phyllodes tumor, showing malignant features on the left and borderline characteristics associated with a fibroadenoma on the right. A further molecular analysis was carried out by an array-Comparative Genomic Hybridization (CGH) to characterize copy-number alterations. Many losses were detected in the malignant mass, involving several tumor suppressor genes. These findings could explain the malignant growth and the metastatic risk. In our study, genomic profiling by an array-CGH revealed a greater chromosomal instability in the borderline mass (40 total defects) than in the malignant (19 total defects) giant phyllodes tumor, reflecting the tumor heterogeneity. Should our results be confirmed with more sensitive and specific molecular tests (DNA sequencing and FISH analysis), they could allow a better selection of patients with adverse pathological features, thus optimizing and improving patient’s management.

Phyllodes tumor of the breast clinical experience and outcomes: A retrospective cohort tertiary hospital experience

2021 ◽  
Vol 51 ◽  
pp. 151702
Author(s):  
Abdulmohsen Alkushi ◽  
Haitham Arabi ◽  
Lolwah Al-Riyees ◽  
Abdulelah M. Aldakheel ◽  
Raed Al Zarah ◽  
...  
Keyword(s):  
Clinical Experience ◽  
Retrospective Cohort ◽  
Phyllodes Tumor ◽  
Tertiary Hospital ◽  
Hospital Experience

Beta‐HCG‐producing phyllodes tumor

2020 ◽  
Vol 26 (3) ◽  
pp. 547-549
Author(s):  
Kristy Fisher ◽  
Kristin Rojas ◽  
Carin Zelkowitz ◽  
Patrick Borgen ◽  
Larry Kiss ◽  
...  
Keyword(s):  
Phyllodes Tumor ◽  
Beta Hcg

Reduction Mammaplasty for Phyllodes Tumor Causing Asymmetry in an Adolescent Female

2003 ◽  
Vol 9 (5) ◽  
pp. 426-427 ◽  
Author(s):  
Mustafa Yilmaz ◽  
Haluk Vayvada ◽  
Adnan Menderes ◽  
Cenk Demirdover ◽  
Ali Barutcu
Keyword(s):  
Reduction Mammaplasty ◽  
Phyllodes Tumor ◽  
Adolescent Female

scholarly journals Malignant Phyllodes Tumor Including Aneurysmal Bone Cyst-Like Areas in Pregnancy - a Case Report and Review of the Literature

Breast Care ◽  
2016 ◽  
Vol 11 (4) ◽  
pp. 291-294 ◽  
Author(s):  
Canan Kelten ◽  
Ceren Boyaci ◽  
Cem Leblebici ◽  
Kemal Behzatoglu ◽  
Didem C. Trabulus ◽  
...  
Keyword(s):  
Case Report ◽  
Bone Cyst ◽  
Clinical Breast Examination ◽  
Phyllodes Tumor ◽  
Breast Cancer Diagnosis ◽  
Left Breast ◽  
Malignant Phyllodes Tumor ◽  
Her Family ◽  
Simple Mastectomy ◽  
Clinical Breast

Background: Malignant phyllodes tumors of the breast are rare biphasic neoplasms. Only few cases related to pregnancy have been reported. Case Report: A 37-year-old woman presented with swelling and pain in her left breast as well as hyperemia on the breast skin, 4 weeks after labor. In her family history, her aunt and maternal cousin had had a breast cancer diagnosis. Clinical evaluation of the patient was consistent with a breast abscess. Therefore, abscess drainage and biopsy from the cavity wall were performed. However, the biopsy was diagnosed as malignant phyllodes tumor. An evaluation by ultrasonography showed a well-defined hypoechoic mass with many cystic spaces covering the entire breast tissue. Therefore, a simple mastectomy was performed. Microscopic examination revealed a high-grade malignant phyllodes tumor. Additionally, bone cyst-like areas in the form of sponge-like blood-filled non-endothelialized spaces were observed. Conclusions: Since the breasts become larger due to the physiological changes during pregnancy, any underlying breast lesions may be obscured. Therefore, clinical breast examination in the first visit of pregnancy is important.

No rearrangement of the CHOP and TLS/FUS genes in two cases of phyllodes tumor of the breast

1996 ◽  
Vol 87 (1) ◽  
pp. 90-91
Author(s):  
Sandra H. Birdsall ◽  
Alasdair C. Stamps ◽  
Barry A. Gusterson ◽  
Janet M. Shipley ◽  
Sandra E. Gill ◽  
...  
Keyword(s):  
Phyllodes Tumor
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