scholarly journals BACH2, a Candidate Risk Gene for Type 1 Diabetes, Regulates Apoptosis in Pancreatic  -Cells via JNK1 Modulation and Crosstalk With the Candidate Gene PTPN2

Diabetes ◽  
2014 ◽  
Vol 63 (7) ◽  
pp. 2516-2527 ◽  
Author(s):  
L. Marroqui ◽  
I. Santin ◽  
R. S. Dos Santos ◽  
L. Marselli ◽  
P. Marchetti ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Candidate Gene ◽  
Risk Gene ◽  
Pancreatic Cells

scholarly journals Restoration of the Unfolded Protein Response in Pancreatic   Cells Protects Mice Against Type 1 Diabetes

2013 ◽  
Vol 5 (211) ◽  
pp. 211ra156-211ra156 ◽  
Author(s):  
F. Engin ◽  
A. Yermalovich ◽  
T. Nguyen ◽  
S. Hummasti ◽  
W. Fu ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Unfolded Protein Response ◽  
Unfolded Protein ◽  
Pancreatic Cells ◽  
The Unfolded Protein Response ◽  
Protein Response

scholarly journals Quantitative Determination of Apoptosis of Pancreatic  -Cells in a Murine Model of Type 1 Diabetes Mellitus

2012 ◽  
Vol 53 (10) ◽  
pp. 1585-1591 ◽  
Author(s):  
A. Watanabe ◽  
K.-i. Nishijima ◽  
S. Zhao ◽  
Y. Zhao ◽  
Y. Tanaka ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Quantitative Determination ◽  
Type 1 Diabetes Mellitus ◽  
Murine Model ◽  
Pancreatic Cells

Identification of the transcription factor ARNTL2 as a candidate gene for the type 1 diabetes locus Idd6

2006 ◽  
Vol 15 (18) ◽  
pp. 2732-2742 ◽  
Author(s):  
Ming-Shiu Hung ◽  
Philip Avner ◽  
Ute Christine Rogner
Keyword(s):  
Type 1 Diabetes ◽  
Transcription Factor ◽  
Candidate Gene

Complete mutation scanning of the human SEL 1L gene: a candidate gene for type 1 diabetes

2001 ◽  
Vol 38 (4) ◽  
pp. 191-192 ◽  
Author(s):  
Z. M. Larsen ◽  
A. D. Angelo ◽  
M. Cattaneo ◽  
J. Nerup ◽  
I. Biunno ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Candidate Gene ◽  
Mutation Scanning

scholarly journals PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Pancreatic  -Cell Apoptosis via Regulation of the BH3-Only Protein Bim

Diabetes ◽  
2011 ◽  
Vol 60 (12) ◽  
pp. 3279-3288 ◽  
Author(s):  
I. Santin ◽  
F. Moore ◽  
M. L. Colli ◽  
E. N. Gurzov ◽  
L. Marselli ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Candidate Gene ◽  
Cell Apoptosis ◽  
Pancreatic Cell

Association of SUMO4, as a Candidate Gene for IDDM5, with Susceptibility to Type 1 Diabetes in Asian Populations

2006 ◽  
Vol 1079 (1) ◽  
pp. 41-46 ◽  
Author(s):  
S. NOSO ◽  
H. IKEGAMI ◽  
T. FUJISAWA ◽  
Y. KAWABATA ◽  
K. ASANO ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Candidate Gene ◽  
Asian Populations

scholarly journals The type 1 diabetes candidate gene Dexi does not affect disease risk in the nonobese diabetic mouse model

2019 ◽  
Vol 21 (1) ◽  
pp. 71-77 ◽  
Author(s):  
Janice M. Nieves-Bonilla ◽  
Badr Kiaf ◽  
Cornelia Schuster ◽  
Stephan Kissler
Keyword(s):  
Type 1 Diabetes ◽  
Mouse Model ◽  
Candidate Gene ◽  
Disease Risk ◽  
Diabetic Mouse ◽  
Nonobese Diabetic Mouse ◽  
Nonobese Diabetic ◽  
Diabetes Candidate Gene

scholarly journals Growth of Rotaviruses in Primary Pancreatic Cells

2002 ◽  
Vol 76 (18) ◽  
pp. 9537-9544 ◽  
Author(s):  
Barbara S. Coulson ◽  
Paul D. Witterick ◽  
Yan Tan ◽  
Marilyn J. Hewish ◽  
Joanne N. Mountford ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Diabetic Mice ◽  
Children At Risk ◽  
Macaque Monkeys ◽  
Rotavirus Infection ◽  
Nonobese Diabetic ◽  
Pancreatic Cells ◽  
Nonobese Diabetic Mice

ABSTRACT Rotavirus infection in children at risk of developing type 1 diabetes has been temporally associated with development of pancreatic islet autoantibodies. In this study, nonobese diabetic mice were shown to be susceptible to rhesus rotavirus infection and pancreatic islets from nonobese diabetic mice, nonobese diabetes-resistant mice, fetal pigs, and macaque monkeys supported various degrees of rotavirus growth. Human rotaviruses replicated in monkey islets only. This islet susceptibility shows that rotavirus infection of the pancreas in vivo might be possible.

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