scholarly journals Extending Remission and Reversing New-Onset Type 1 Diabetes by Targeted Ablation of Autoreactive T Cells

Diabetes ◽  
2018 ◽  
Vol 67 (11) ◽  
pp. 2319-2328
Author(s):  
Kaitlin R. Carroll ◽  
Eileen E. Elfers ◽  
Joseph J. Stevens ◽  
Jonathan P. McNally ◽  
David A. Hildeman ◽  
...  
Keyword(s):  
T Cells ◽  
Type 1 Diabetes ◽  
Autoreactive T Cells ◽  
Onset Type ◽  
New Onset

2. Durable Efficacy of Alefacept in New-Onset Type 1 Diabetes: Evidence for Lasting Modulation of Effector and Regulatory T Cells (231-OR)

2015 ◽  
Vol 13 (3) ◽  
pp. 56-57
Author(s):  
Mark R. Rigby ◽  
Kristina M. Harris ◽  
Ashley Pinckney ◽  
Linda A. Dimeglio ◽  
Marc S. Rendell ◽  
...  
Keyword(s):  
T Cells ◽  
Type 1 Diabetes ◽  
Regulatory T Cells ◽  
Onset Type ◽  
New Onset

scholarly journals Programmed cell death-1, PD-1, is dysregulated in T cells from children with new onset type 1 diabetes

PLoS ONE ◽  
2017 ◽  
Vol 12 (9) ◽  
pp. e0183887 ◽  
Author(s):  
Hector M. Granados ◽  
Andrew Draghi ◽  
Naomi Tsurutani ◽  
Kyle Wright ◽  
Marina L. Fernandez ◽  
...  
Keyword(s):  
T Cells ◽  
Cell Death ◽  
Type 1 Diabetes ◽  
Programmed Cell Death ◽  
Onset Type ◽  
Programmed Cell Death 1 ◽  
New Onset

scholarly journals Targeting of memory T cells with alefacept in new-onset type 1 diabetes (T1DAL study): 12 month results of a randomised, double-blind, placebo-controlled phase 2 trial

2013 ◽  
Vol 1 (4) ◽  
pp. 284-294 ◽  
Author(s):  
Mark R Rigby ◽  
Linda A DiMeglio ◽  
Marc S Rendell ◽  
Eric I Felner ◽  
Jean M Dostou ◽  
...  
Keyword(s):  
T Cells ◽  
Type 1 Diabetes ◽  
Memory T Cells ◽  
Phase 2 ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Onset Type ◽  
Phase 2 Trial ◽  
New Onset

scholarly journals Partial exhaustion of CD8 T cells and clinical response to teplizumab in new-onset type 1 diabetes

2016 ◽  
Vol 1 (5) ◽  
pp. eaai7793-eaai7793 ◽  
Author(s):  
S. A. Long ◽  
J. Thorpe ◽  
H. A. DeBerg ◽  
V. Gersuk ◽  
J. A. Eddy ◽  
...  
Keyword(s):  
T Cells ◽  
Type 1 Diabetes ◽  
Clinical Response ◽  
Cd8 T Cells ◽  
Onset Type ◽  
New Onset

scholarly journals Cutting Edge: Increased IL-17–Secreting T Cells in Children with New-Onset Type 1 Diabetes

2010 ◽  
Vol 185 (7) ◽  
pp. 3814-3818 ◽  
Author(s):  
Ashish K. Marwaha ◽  
Sarah Q. Crome ◽  
Constadina Panagiotopoulos ◽  
Kyra B. Berg ◽  
Huilian Qin ◽  
...  
Keyword(s):  
T Cells ◽  
Type 1 Diabetes ◽  
Cutting Edge ◽  
Onset Type ◽  
New Onset

Natural Killer T Cells (NKT) in Children with New Onset Type 1 Diabetes

2013 ◽  
Vol 12 (1) ◽  
pp. 9-16
Author(s):  
Robert Piekarski ◽  
◽  
Leszek Szewczyk ◽  
Agnieszka Bojarska-Junak ◽  
◽  
...  
Keyword(s):  
T Cells ◽  
Type 1 Diabetes ◽  
Natural Killer ◽  
Natural Killer T Cells ◽  
Onset Type ◽  
Killer T Cells ◽  
New Onset ◽  
Natural Killer T

scholarly journals Reversal of New Onset Type 1 Diabetes by Oral Salmonella-Based Combination Therapy and Mediated by Regulatory T-Cells in NOD Mice

2019 ◽  
Vol 10 ◽  
Author(s):  
Jacques C. Mbongue ◽  
Jeffrey Rawson ◽  
Pablo A. Garcia ◽  
Nelson Gonzalez ◽  
Jacob Cobb ◽  
...  
Keyword(s):  
T Cells ◽  
Type 1 Diabetes ◽  
Regulatory T Cells ◽  
Combination Therapy ◽  
Nod Mice ◽  
Onset Type ◽  
New Onset

16-OR: Codesigning an Intervention for Adults with New-Onset Type 1 Diabetes to Improve Psychological and Social Adaptation

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 16-OR
Author(s):  
METTE DUE-CHRISTENSEN ◽  
LENE E. JOENSEN ◽  
SOPHIE SARRE ◽  
JULIE L. WAD ◽  
EWA ROMANCZUK ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Social Adaptation ◽  
Onset Type ◽  
New Onset
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