scholarly journals A1C Variability and the Risk of Microvascular Complications in Type 1 Diabetes: Data from the Diabetes Control and Complications Trial

Diabetes Care ◽  
2008 ◽  
Vol 31 (11) ◽  
pp. 2198-2202 ◽  
Author(s):  
E. S. Kilpatrick ◽  
A. S. Rigby ◽  
S. L. Atkin
2008 ◽  
Vol 04 (01) ◽  
pp. 62 ◽  
Author(s):  
Jonathan Purnell

The Diabetes Control and Complications Trial (DCCT) was a prospective, randomised, controlled clinical trial that began in the 1980s and was carried out over a decade to determine whether intensive treatment aimed at maintaining blood glucose concentrations close to the normal range could decrease the frequency and severity of microvascular complications in patients with type 1 diabetes. The results showed that intensive therapy effectively delays the onset and progression of diabetic retinopathy, nephropathy, and neuropathy in patients with type 1 diabetes.1The side effects associated with intensive therapy were a nearly three-fold increased frequency of severe hypoglycaemia and greater weight gain. For the majority of patients with type 1 diabetes, the benefits of intensive therapy were considered to vastly outweigh these risks. However, the potential detrimental effects of weight gain, especially on macrovascular risks, are being revisited.


2017 ◽  
Author(s):  
Yuliya Dydyshka ◽  
Alla Shepelkevich ◽  
Vladislav Yurkovets ◽  
Elena Brutskaya-Stempkovskaya ◽  
Marina Mantachik

2018 ◽  
Author(s):  
Jan Idkowiak ◽  
Sabba Elhag ◽  
Vrinda Saraff ◽  
Renuka Dias ◽  
Timothy Barrett ◽  
...  

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 38-LB
Author(s):  
ANDRZEJ S. JANUSZEWSKI ◽  
EMMA S. SCOTT ◽  
MUGDHA JOGLEKAR ◽  
LUKE CARROLL ◽  
RYAN FARR ◽  
...  

Author(s):  
David S. Greene ◽  
Nancy Dunavant King

Abstract There is increasing evidence of specific medical and psychological benefits associated with humor within diabetes populations. The benefits of maintaining good diabetes control are also well established. The more general relationship between humor and diabetes control however remains unexplored. The purpose of this study was to examine if there was a difference between people with diabetes with an A1C ≤ 6.99% versus those ≥7.0% on four disparate types of humor. The sample consisted of 284 participants, 65.5% with type 1 diabetes, 68.3% female, 89.1% Caucasian, and 68.7% college educated. Participants completed the Humor Styles Questionnaire (HSQ) and were divided into two groups, A1C ≤ 6.99% and A1C ≥ 7.0%. The A1C ≤ 6.99% group scored significantly higher on both types of positive humor, affiliative humor (P < 0.01) and self-enhancing humor (P < 0.05). There was no significant difference between participants on either type of negative humor, aggressive humor (P > 0.05) or self-defeating humor (P > 0.05). Results indicate that good control (A1C ≤ 6.99%) is associated with positive humor. These findings provide evidence that there is an association between American Diabetes Association recommended levels of control and positive humor styles. Implications regarding positive humor and good diabetes control are discussed.


Sign in / Sign up

Export Citation Format

Share Document