Polymorphic human glucose transporter gene (GLUT) is on chromosome 1p31.3----p35

Diabetes ◽  
1987 ◽  
Vol 36 (4) ◽  
pp. 546-549 ◽  
Author(s):  
T. B. Shows ◽  
R. L. Eddy ◽  
M. G. Byers ◽  
Y. Fukushima ◽  
C. R. Dehaven ◽  
...  
Keyword(s):  
Glucose Transporter ◽  
Transporter Gene

scholarly journals Glucose transporter gene expression in rat conceptus during high glucose culture

Diabetologia ◽  
1993 ◽  
Vol 36 (8) ◽  
pp. 696-706 ◽  
Author(s):  
Y. Takao ◽  
S. Akazawa ◽  
K. Matsumoto ◽  
H. Takino ◽  
M. Akazawa ◽  
...  
Keyword(s):  
Gene Expression ◽  
High Glucose ◽  
Glucose Transporter ◽  
Transporter Gene

scholarly journals Essential role of glucose transporter GLUT3 for post-implantation embryonic development

2008 ◽  
Vol 200 (1) ◽  
pp. 23-33 ◽  
Author(s):  
S Schmidt ◽  
A Hommel ◽  
V Gawlik ◽  
R Augustin ◽  
N Junicke ◽  
...  
Keyword(s):  
Essential Role ◽  
Glucose Transporter ◽  
Growth Arrest ◽  
Complete Loss ◽  
Transporter Gene ◽  
Wild Type ◽  
Post Implantation ◽  
Time Point

Deletion of glucose transporter geneSlc2a3(GLUT3) has previously been reported to result in embryonic lethality. Here, we define the exact time point of growth arrest and subsequent death of the embryo.Slc2a3−/−morulae and blastocysts developed normally, implantedin vivo, and formed egg-cylinder-stage embryos that appeared normal until day 6.0. At day 6.5, apoptosis was detected in the ectodermal cells ofSlc2a3−/−embryos resulting in severe disorganization and growth retardation at day 7.5 and complete loss of embryos at day 12.5. GLUT3 was detected in placental cone, in the visceral ectoderm and in the mesoderm of 7.5-day-old wild-type embryos. Our data indicate that GLUT3 is essential for the development of early post-implanted embryos.

scholarly journals Lactose-over-Glucose Preference in Bifidobacterium longum NCC2705: glcP, Encoding a Glucose Transporter, Is Subject to Lactose Repression

2006 ◽  
Vol 188 (4) ◽  
pp. 1260-1265 ◽  
Author(s):  
Stephan Parche ◽  
Manfred Beleut ◽  
Enea Rezzonico ◽  
Doris Jacobs ◽  
Fabrizio Arigoni ◽  
...  
Keyword(s):  
Glucose Transport ◽  
Culture Medium ◽  
Glucose Transporter ◽  
Glucose Utilization ◽  
Bifidobacterium Longum ◽  
Global Gene Expression ◽  
Dna Arrays ◽  
Transporter Gene ◽  
Global Gene Expression Profiling ◽  
Culture Supernatants

ABSTRACT Analysis of culture supernatants obtained from Bifidobacterium longum NCC2705 grown on glucose and lactose revealed that glucose utilization is impaired until depletion of lactose. Thus, unlike many other bacteria, B. longum preferentially uses lactose rather than glucose as the primary carbon source. Glucose uptake experiments with B. longum cells showed that glucose transport was repressed in the presence of lactose. A comparative analysis of global gene expression profiling using DNA arrays led to the identification of only one gene repressed by lactose, the putative glucose transporter gene glcP. The functionality of GlcP as glucose transporter was demonstrated by heterologous complementation of a glucose transport-deficient Escherichia coli strain. Additionally, GlcP exhibited the highest substrate specificity for glucose. Primer extension and real-time PCR analyses confirmed that expression of glcP was mediated by lactose. Hence, our data demonstrate that the presence of lactose in culture medium leads to the repression of glucose transport and transcriptional down-regulation of the glucose transporter gene glcP. This may reflect the highly adapted life-style of B. longum in the gastrointestinal tract of mammals.

scholarly journals Variability of the pancreatic islet beta cell/liver (GLUT 2) glucose transporter gene in NIDDM patients

Diabetologia ◽  
1994 ◽  
Vol 37 (4) ◽  
pp. 420-427 ◽  
Author(s):  
Y. Tanizawa ◽  
A. C. Riggs ◽  
J. M. Roseman ◽  
M. A. Permutt ◽  
K. C. Chiu ◽  
...  
Keyword(s):  
Beta Cell ◽  
Pancreatic Islet ◽  
Glucose Transporter ◽  
Transporter Gene ◽  
Islet Beta Cell ◽  
Pancreatic Islet Beta Cell ◽  
Niddm Patients

scholarly journals A novel allele of the ADP-glucose transporter gene in ‘Tanikei QM-1’ markedly increases health-promoting compounds in barley grains

2018 ◽  
Vol 20 (2) ◽  
pp. 124-132
Author(s):  
Masaru Nakata ◽  
Tatsuya M. Ikeda ◽  
Yasunori Ichinose ◽  
Yoichi Nogata ◽  
Masako Seki ◽  
...  
Keyword(s):  
Glucose Transporter ◽  
Transporter Gene ◽  
Health Promoting ◽  
Barley Grains ◽  
Novel Allele
Sign in / Sign up

Export Citation Format

Share Document