Skin Chromophore Estimation from Mobile Selfie Images using Constrained Independent Component Analysis

2020 ◽  
Vol 2020 (14) ◽  
pp. 357-1-357-6
Author(s):  
Luisa F. Polanía ◽  
Raja Bala ◽  
Ankur Purwar ◽  
Paul Matts ◽  
Martin Maltz

Human skin is made up of two primary chromophores: melanin, the pigment in the epidermis giving skin its color; and hemoglobin, the pigment in the red blood cells of the vascular network within the dermis. The relative concentrations of these chromophores provide a vital indicator for skin health and appearance. We present a technique to automatically estimate chromophore maps from RGB images of human faces captured with mobile devices such as smartphones. The ultimate goal is to provide a diagnostic aid for individuals to monitor and improve the quality of their facial skin. A previous method approaches the problem as one of blind source separation, and applies Independent Component Analysis (ICA) in camera RGB space to estimate the chromophores. We extend this technique in two important ways. First we observe that models for light transport in skin call for source separation to be performed in log spectral reflectance coordinates rather than in RGB. Thus we transform camera RGB to a spectral reflectance space prior to applying ICA. This process involves the use of a linear camera model and Principal Component Analysis to represent skin spectral reflectance as a lowdimensional manifold. The camera model requires knowledge of the incident illuminant, which we obtain via a novel technique that uses the human lip as a calibration object. Second, we address an inherent limitation with ICA that the ordering of the separated signals is random and ambiguous. We incorporate a domain-specific prior model for human chromophore spectra as a constraint in solving ICA. Results on a dataset of mobile camera images show high quality and unambiguous recovery of chromophores.

2013 ◽  
Vol 380-384 ◽  
pp. 3678-3681 ◽  
Author(s):  
Gao Ling ◽  
Shou Xin Ren

A multi-dimensional data processing method, independent component analysis-based principal component regression (ICA-PCR) was developed for simultaneous kinetic determination of Cu (II), Fe (III) and Ni (II). Independent component analysis is a newly developed signal processing technique aiming at solving related blind source separation (BSS) problem. One program, PICAPCR, was designed to perform relative calculations. Experimental results showed the ICA-PCR method to be successful for simultaneous multicomponent kinetic determination even where there was severe overlap of spectra.


Author(s):  
Miguel A. Ferrer ◽  
Aday Tejera Santana

This work presents a brief introduction to the blind source separation using independent component analysis (ICA) techniques. The main objective of the blind source separation (BSS) is to obtain, from observations composed by different mixed signals, those different signals that compose them. This objective can be reached using two different techniques, the spatial and the statistical one. The first one is based on a microphone array and depends on the position and separation of them. It also uses the directions of arrival (DOA) from the different audio signals. On the other hand, the statistical separation supposes that the signals are statistically independent, that they are mixed in a linear way and that it is possible to get the mixtures with the right sensors (Hyvärinen, Karhunen & Oja, 2001) (Parra, 2002). The last technique is the one that is going to be studied in this work. It is due to this technique is the newest and is in a continuous development. It is used in different fields such as natural language processing (Murata, Ikeda & Ziehe, 2001) (Saruwatari, Kawamura & Shikano, 2001), bioinformatics, image processing (Cichocki & Amari, 2002) and in different real life applications such as mobile communications (Saruwatari, Sawai, Lee, Kawamura, Sakata & Shikano, 2003). Specifically, the technique that is going to be used is the Independent Component Analysis (ICA). ICA comes from an old technique called PCA (Principal Component Analysis) (Hyvärinen, Karhunen & Oja, 2001) (Smith, 2006). PCA is used in a wide range of scopes such as face recognition or image compression, being a very common technique to find patterns in high dimension data. The BSS problem can be of two different ways; the first one is when the mixtures are linear. It means that the data are mixed without echoes or reverberations, while the second one, due to these conditions, the mixtures are convolutive and they are not totally independent because of the signal propagation through dynamic environments. It is the “Cocktail party problem”. Depending on the mixtures, there are several methods to solve the BSS problem. The first case can be seen as a simplification of the second one. The blind source separation based on ICA is also divided into three groups; the first one are those methods that works in the time domain, the second are those who works in the frequency domain and the last group are those methods that combine frequency and time domain methods. A revision of the technique state of these methods is proposed in this work.


2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Carlos G. Urzúa-Traslaviña ◽  
Vincent C. Leeuwenburgh ◽  
Arkajyoti Bhattacharya ◽  
Stefan Loipfinger ◽  
Marcel A. T. M. van Vugt ◽  
...  

AbstractThe interpretation of high throughput sequencing data is limited by our incomplete functional understanding of coding and non-coding transcripts. Reliably predicting the function of such transcripts can overcome this limitation. Here we report the use of a consensus independent component analysis and guilt-by-association approach to predict over 23,000 functional groups comprised of over 55,000 coding and non-coding transcripts using publicly available transcriptomic profiles. We show that, compared to using Principal Component Analysis, Independent Component Analysis-derived transcriptional components enable more confident functionality predictions, improve predictions when new members are added to the gene sets, and are less affected by gene multi-functionality. Predictions generated using human or mouse transcriptomic data are made available for exploration in a publicly available web portal.


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