Preoperative virtual bronchoscopy and fluoroscopic-guided transbronchial biopsy allowed amyloidosis diagnosis

Background/need. The increases in reference images and information during bronchoscopy using virtual bronchoscopic navigation (VBN) and fluoroscopy has potentially created the need for support using a head-mounted display (HMD) because bronchoscopists feel difficulty to see displays that are at a distance from them and turn their head and body in various directions. Methodology and device description. The binocular see-through Moverio BT-35E Smart Glasses can be connected via a high-definition multimedia interface and have a 720p high-definition display. We developed a system that converts fluoroscopic (live and reference), VBN, and bronchoscopic image signals through a converter and references them using the Moverio BT-35E. Preliminary results. We performed a virtual bronchoscopy-guided transbronchial biopsy simulation using the system. Four experienced pulmonologists performed a simulated bronchoscopy of 5 cases each with the Moverio BT-35E glasses, using bronchoscopy training model. For all procedures, the bronchoscope was advanced successfully into the target bronchus according to the VBN image. None of the operators reported eye or body fatigue during or after the procedure. Current status. This small-scale simulation study suggests the feasibility of using a HMD during bronchoscopy. For clinical use, it is necessary to evaluate the safety and usefulness of the system in larger clinical trials in the future.

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Two Cases of Peripheral Small Adenocarcinoma of the Lung Diagnosed by CT-guided Transbronchial Biopsy Using Virtual Bronchoscopy, and Treated With Stereotactic Radiotherapy

Haigan ◽

10.2482/haigan.43.47 ◽

2003 ◽

Vol 43 (1) ◽

pp. 47-51

Author(s):

Naofumi Shinagawa ◽

Koichi Yamazaki ◽

Yoko Ishibashi ◽

Yuya Onodera ◽

Hirotoshi Akita(Dosaka) ◽

...

Keyword(s):

Stereotactic Radiotherapy ◽

Transbronchial Biopsy ◽

Virtual Bronchoscopy ◽

Ct Guided ◽

Adenocarcinoma Of The Lung

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Utility of Virtual Bronchoscopy-Guided Transbronchial Biopsy for the Diagnosis of Pulmonary Sarcoidosis

CHEST Journal ◽

10.1378/chest.08-0052 ◽

2008 ◽

Vol 134 (3) ◽

pp. 630-636 ◽

Cited By ~ 10

Author(s):

Myrna C.B. Godoy ◽

David Ost ◽

Bernhard Geiger ◽

Carol Novak ◽

Daisuke Nonaka ◽

...

Keyword(s):

Pulmonary Sarcoidosis ◽

Transbronchial Biopsy ◽

Virtual Bronchoscopy

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The accuracy of non-invasive 3D-CT virtual bronchoscopy technique in comparison with invasive technique

International Journal of Medicine in Developing Countries ◽

10.24911/ijmdc.51-1538516450 ◽

2019 ◽

pp. 1

Author(s):

Basmah Altuwayjiri

Keyword(s):

Invasive Technique ◽

Virtual Bronchoscopy ◽

3D Ct ◽

Non Invasive

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Transbronchial biopsy after lung transplantation

Journal of Thoracic and Cardiovascular Surgery ◽

10.1016/s0022-5223(19)36668-1 ◽

1991 ◽

Vol 101 (5) ◽

pp. 935-936 ◽

Cited By ~ 2

Author(s):

John P. Scott ◽

Rosalind L. Smyth ◽

Tim Higenbottam ◽

Paul Mullins ◽

Eduardo Solis ◽

...

Keyword(s):

Lung Transplantation ◽

Transbronchial Biopsy

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Finger clubbing and cirrhosis in a sarcoidosis patient

Monaldi Archives for Chest Disease ◽

10.4081/monaldi.2019.1141 ◽

2019 ◽

Vol 89 (3) ◽

Author(s):

Halil Yanardag ◽

Cuneyt Tetikkurt ◽

Muammer Bilir

Keyword(s):

Portal Hypertension ◽

Liver Biopsy ◽

Physical Examination ◽

Final Diagnosis ◽

Transbronchial Biopsy ◽

Chest Ct ◽

Inflammatory Disorder ◽

Sarcoidosis Patient ◽

Urinary Analysis ◽

Serologic Markers

Sarcoidosis is a multisystem granulomatous inflammatory disorder frequently affecting the lungs, but also the liver, along with cirrhosis and portal hypertension occurring in less than 1% of the patients. A 56-year-old female presented with dyspnea, abdominal and leg swelling. Physical examination revealed finger clubbing, ascites and pretibial edema. Chest CT revealed diffuse micronodular opacities in both lungs without any enlarged thoracic lymph nodes. PFTs and DLCO/VA were moderately decreased. Transbronchial biopsy revealed non-caseified granulomas compatible with sarcoidosis. Serologic markers for infectious and autoimmune hepatitis were negative. Liver biopsy showed non-caseating granulomas, severe hepatitis and fibrosis. Stool, urinary analysis and antibodies for Schistosoma infection were negative. Final diagnosis was cirrhosis associated with stage III sarcoidosis. We report a case of sarcoidosis complicated by cirrhosis and portal hypertension with finger clubbing. Clinicians should bear in mind that cirrhosis, portal hypertension and clubbing may arise as the initial manifestations of sarcoidosis.

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