scholarly journals Absorbed Radiation Dose in the Thyroid Gland Following Regional Nodal Irradiation for Breast Cancer

2018 ◽  
Vol 1 (2) ◽  
Author(s):  
Nageeti Tahani ◽  
Mahfouz Mohamed ◽  
Gaod Mazen Al ◽  
Zatar Reem
Keyword(s):  
Breast Cancer ◽  
Thyroid Gland ◽  
Radiation Dose ◽  
Regional Nodal Irradiation ◽  
Absorbed Radiation Dose

scholarly journals Analysis of Radiation Dose to the Shoulder by Treatment Technique and Correlation With Patient Reported Outcomes in Patients Receiving Regional Nodal Irradiation

2021 ◽  
Vol 11 ◽  
Author(s):  
Jose G. Bazan ◽  
Dominic DiCostanzo ◽  
Karen Hock ◽  
Sachin Jhawar ◽  
Karla Kuhn ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Radiation Therapy ◽  
Radiation Dose ◽  
Patient Reported Outcomes ◽  
Late Complication ◽  
Treatment Technique ◽  
Regional Nodal Irradiation ◽  
Patient Reported ◽  
The Impact ◽  
Dash Questionnaire

Background/PurposeShoulder/arm morbidity is a late complication of breast cancer treatment with surgery and regional nodal irradiation (RNI). We set to analyze the impact of radiation technique [intensity modulated radiation therapy (IMRT) or 3D conformal radiation therapy (3DCRT)] on radiation dose to the shoulder with a hypothesis that IMRT use results in smaller volume of shoulder receiving radiation. We explored the relationship of treatment technique on long-term patient-reported outcomes using the quick disabilities of the arm, shoulder, and hand (q-DASH) questionnaire.Materials/MethodsWe identified patients treated with adjuvant RNI (50 Gy/25 fractions) from 2013 to 2018. We retrospectively contoured the shoulder organ-at-risk (OAR) from 2 cm above the ipsilateral supraclavicular (SCL) planning target volume (PTV) to the inferior SCL PTV slice and calculated the absolute volume of shoulder OAR receiving 5–50 Gy (V5–V50). We identified patients that completed a q-DASH questionnaire ≥6 months from the end of RNI.ResultsWe included 410 RNI patients: 54% stage III, 72% mastectomy, 35% treated with IMRT. IMRT resulted in significant reductions in the shoulder OAR volume receiving 20–50 Gy vs. 3DCRT. In total, 82 patients completed the q-DASH. The mean (SD) q-DASH=25.4 (19.1) and tended to be lower with IMRT vs. 3DCRT: 19.6 (16.4) vs. 27.8 (19.8), p=0.078.ConclusionWe found that IMRT reduces radiation dose to the shoulder and is associated with a trend toward reduced q-DASH scores ≥6 months post-RNI in a subset of our cohort. These results support prospective evaluation of IMRT as a technique to reduce shoulder morbidity in breast cancer patients receiving RNI.

scholarly journals Evaluation of the Absorbed Radiation Dose for Thyroid Gland in Chest Tumor Radiotherapy

2019 ◽  
Vol 105 (1) ◽  
pp. E745
Author(s):  
Y. Wang ◽  
L. He ◽  
M. Zheng ◽  
J. Wang ◽  
J. Xu ◽  
...  
Keyword(s):  
Thyroid Gland ◽  
Radiation Dose ◽  
Absorbed Radiation Dose

scholarly journals Absorbed Radiation Dose in Radiosensitive Organs Using 64- and 320-Row Multidetector Computed Tomography: A Comparative Study

Scientifica ◽  
2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Atif N. Khan ◽  
Waqas Shuaib ◽  
Boris Nikolic ◽  
Mohammad K. Khan ◽  
Jian Kang ◽  
...  
Keyword(s):  
Heart Rate ◽  
Thyroid Gland ◽  
Radiation Dose ◽  
Radiation Detectors ◽  
Imaging Protocol ◽  
Retrospective Gating ◽  
Absorbed Radiation Dose ◽  
Dose Modulation ◽  
Radiosensitive Organs ◽  
Gated Imaging

Aim. To determine absorbed radiation dose (ARD) in radiosensitive organs during prospective and full phase dose modulation using ECG-gated MDCTA scanner under 64- and 320-row detector modes.Methods. Female phantom was used to measure organ radiation dose. Five DP-3 radiation detectors were used to measure ARD to lungs, breast, and thyroid using the Aquilion ONE scanner in 64- and 320-row modes using both prospective and dose modulation in full phase acquisition. Five measurements were made using three tube voltages: 100, 120, and 135 kVp at 400 mA at heart rate (HR) of 60 and 75 bpm for each protocol. Mean acquisition was recorded in milligrays (mGy).Results. Mean ARD was less for 320-row versus 64-row mode for each imaging protocol. Prospective EKG-gated imaging protocol resulted in a statistically lower ARD using 320-row versus 64-row modes for midbreast (6.728 versus 19.687 mGy,P<0.001), lung (6.102 versus 21.841 mGy,P<0.001), and thyroid gland (0.208 versus 0.913 mGy;P<0.001). Retrospective imaging using 320- versus 64-row modes showed lower ARD for midbreast (10.839 versus 43.169 mGy,P<0.001), lung (8.848 versus 47.877 mGy,P<0.001), and thyroid gland (0.057 versus 2.091 mGy;P<0.001). ARD reduction was observed at lower kVp and heart rate.Conclusions. Dose reduction to radiosensitive organs is achieved using 320-row compared to 64-row modes for both prospective and retrospective gating, whereas 64-row mode is equivalent to the same model 64-row MDCT scanner.

Effect of change in neck position on thyroid dose and volume in supraclavicular irradiation for breast cancer using conformal technique

2021 ◽  
pp. 1-5
Author(s):  
Sajeev George Pulickal ◽  
Nikhil Sebastian ◽  
Reshma Bhaskaran ◽  
P Aparna
Keyword(s):  
Breast Cancer ◽  
Thyroid Gland ◽  
Radiation Dose ◽  
Thyroid Volume ◽  
Contralateral Side ◽  
Neck Position ◽  
Significant Difference ◽  
Thyroid Dose ◽  
Radiation Planning

Abstract Background and aim: Radiation exposure to the thyroid gland during breast irradiation can lead to hypothyroidism and this can impact on the quality of life. The aim of this study was to analyse if there is any difference in the radiation dose received by the thyroid gland during supraclavicular irradiation for breast cancer, with two different neck positions—straight or when the head is turned to the contralateral side to the breast being treated, when using a conformal technique. Materials and methods: All patients who received chest wall/breast and supraclavicular irradiation for breast cancer in 2019 in our department were divided into two groups based on the neck position as SN (neck positioned straight) and TN (neck tilted to contralateral side). The volume of thyroid gland, the radiation dose and volume parameters for Dmax, Dmean, and V5 to V40 of the thyroid were tabulated. Results: There were 72 patients included in the study with a mean age of 59 years, with 39 in the SN group and 33 in the TN group. There was no significant difference in thyroid volume between the two groups. Dmean, V15, V20, V25, V30 and V35 were significantly lower in tilted neck patients as compared to straight neck patients. Conclusion: Neck positioned to the contralateral side of the breast primary may be recommended for conformal CT-based radiation planning.

The Effect of Carbimazole Following Radioiodine Therapy on Radiation Dose to the Thyroid

1981 ◽  
Vol 20 (02) ◽  
pp. 72-75 ◽  
Author(s):  
R. Kocak ◽  
R.G. Herbert ◽  
C.R. Squire ◽  
T.M.D. Gimlette
Keyword(s):  
Thyroid Gland ◽  
Radiation Dose ◽  
Half Life ◽  
Radioiodine Therapy

Radioiodine in the thyroid gland after a therapy dose of 131I was measured serially in 7 patients without Carbimazole, and in 11 patients starting Carbimazole 60 mg daily fourteen days after the therapy dose. Effective half-life for radioiodine in the gland initially 5.53±1.08 days fell to 4.26±1.12 days (p < 0.01) during Carbimazole, and returned to 5.83±1.21 days (NS) after stopping the drug. The radiation dose to the thyroid from a given therapy dose of 131I followed by Carbimazole was calculated to be 97% of that without Carbimazole when the drug was started after 14 days, and 90% and 75% when the drug was started after 7 days and 1 day respectively.

The effect of dynamic wedge angle in breast cancer's absorbed radiation dose

2020 ◽  
Author(s):  
Nurul Fitriyah ◽  
Rahmatul Izza Nur Amalia ◽  
Bambang Haris Suhartono ◽  
Suryani Dyah Astuti
Keyword(s):  
Radiation Dose ◽  
Wedge Angle ◽  
Dynamic Wedge ◽  
Absorbed Radiation Dose
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