An Unusual Atrial Septal Defect Producing Symptoms in a Young Lady

Atrial septal defect is the most common congenital heart disease among adult population. Secundum variety of atrial septal defect comprises most frequently encountered atrial septal anomaly which presents during late age. Primum atrial septal defect usually associated with atrio-ventricular cushion defect among patients with Down syndrome. Small number of patients may present with fenestrated atrial septal defect. We have presented case of a woman who is young and symptomatic due to atrial septal defect comprising both secundum and primum type.

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A case of atrial septal defect presenting with recurrent syncope

Malaysian Family Physician ◽

10.51866/cr1125 ◽

2021 ◽

Vol 16 (2) ◽

pp. 90-93

Author(s):

Seng Wee Cheo ◽

Qin Jian Low

Keyword(s):

Congenital Heart Disease ◽

Pulmonary Hypertension ◽

Heart Disease ◽

Atrial Septal Defect ◽

Congenital Heart ◽

Septal Defect ◽

Adult Population ◽

Eisenmenger Syndrome ◽

Progressive Dyspnoea

Atrial septal defect (ASD) is a congenital heart disease often encountered in the adult population, as it is frequently asymptomatic in childhood. In untreated patients with ASD, some may go on to develop complications such as atrial arrythmias, pulmonary hypertension and Eisenmenger syndrome. Pulmonary hypertension is seen in 6 – 35% of this group of untreated patients in adulthood as a result of left-to-right shunting. Symptoms of pulmonary hypertension include progressive dyspnoea, ascites and syncope. Here, we would like to illustrate a case of ASD presenting with recurrent syncopal attack.

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Down syndrome: Prevalence and distribution of congenital heart disease in Brazil

Sao Paulo Medical Journal ◽

10.1590/1516-3180.2015.00710108 ◽

2015 ◽

Vol 133 (6) ◽

pp. 521-524 ◽

Cited By ~ 10

Author(s):

Beatriz Elizabeth Bagatin Veleda Bermudez ◽

Sandra Lira Medeiros ◽

Mariane Bagatin Bermudez ◽

Iolanda Maria Novadzki ◽

Neiva Isabel Rodrigues Magdalena

Keyword(s):

Congenital Heart Disease ◽

Down Syndrome ◽

Heart Disease ◽

Ventricular Septal Defect ◽

Atrial Septal Defect ◽

Outpatient Clinic ◽

Congenital Heart ◽

Septal Defect ◽

Genetic Disorder ◽

High Prevalence

ABSTRACT CONTEXT AND OBJECTIVE: Down syndrome is the most common genetic disorder, affecting 1/700 live births. Among the clinical findings, one constant concern is the high prevalence of congenital heart disease. The objective of this study was to determine the prevalence and profile of congenital heart disease among patients attended at a Down syndrome outpatient clinic in southern Brazil between 2005 and 2013. DESIGN AND SETTING : Cross-sectional study conducted in a referral center. METHODS : Data were retrospectively gathered from the medical files of 1,207 patients with Down syndrome, among whom 604 (50.0%) had been diagnosed with congenital heart disease. These data were subjected to descriptive analysis using the Statistica software. RESULTS : Among the 604 patients with congenital heart disease, 338 (55.8%) were male and 269 (44.5%) were female. The most common heart diseases were atrial septal defect in 254 patients (42.1%); total atrioventricular septal defect in 91 (15.1%); atrial septal defect and ventricular septal defect in 88 (14.6%); ventricular septal defect in 77 (12.7%); patent ductus arteriosus in 40 (6.6%); patent foramen ovale in 34 (5.6%) patients; tetralogy of Fallot in 12 (2%); and other diseases in 8 (1.3%). Pulmonary hypertension was present in 57 (9.4%). Out of the total, 150 patients (24.8%) underwent cardiac surgery. CONCLUSION : The high prevalence of congenital heart disease among the patients at the Down syndrome outpatient clinic (50%) was similar to findings from other studies and justifies investigation during the neonatal period, so as to decrease mortality and morbidity.

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Prevalence and profile of congenital heart disease and pulmonary hypertension in Down syndrome in a pediatric cardiology service

Revista Paulista de Pediatria ◽

10.1590/0103-0582201432218913 ◽

2014 ◽

Vol 32 (2) ◽

pp. 159-163 ◽

Cited By ~ 17

Author(s):

Felipe Alves Mourato ◽

Lúcia Roberta R. Villachan ◽

Sandra da Silva Mattos

Keyword(s):

Congenital Heart Disease ◽

Pulmonary Hypertension ◽

Down Syndrome ◽

Heart Disease ◽

Congenital Heart ◽

Septal Defect ◽

Heart Diseases ◽

Heart Defects ◽

Descriptive Analysis ◽

Atrioventricular Septal Defect

OBJECTIVE:To determine the frequence and profile of congenital heart defects in Down syndrome patients referred to a pediatric cardiologic center, considering the age of referral, gender, type of heart disease diagnosed by transthoracic echocardiography and its association with pulmonary hypertension at the initial diagnosis.METHODS:Cross-sectional study with retrospective data collection of 138 patients with Down syndrome from a total of 17,873 records. Descriptive analysis of the data was performed, using Epi-Info version 7.RESULTS: Among the 138 patients with Down syndrome, females prevailed (56.1%) and 112 (81.2%) were diagnosed with congenital heart disease. The most common lesion was ostium secundum atrial septal defect, present in 51.8%, followed by atrioventricular septal defect, in 46.4%. Ventricular septal defects were present in 27.7%, while tetralogy of Fallot represented 6.3% of the cases. Other cardiac malformations corresponded to 12.5%. Pulmonary hypertension was associated with 37.5% of the heart diseases. Only 35.5% of the patients were referred before six months of age.CONCLUSIONS: The low percentage of referral until six months of age highlights the need for a better tracking of patients with Down syndrome in the context of congenital heart disease, due to the high frequency and progression of pulmonary hypertension.

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Atrial Septal Defect: An Investigation into the Natural History of a Congenital Heart Disease

JAMA ◽

10.1001/jama.1961.03040030085035 ◽

1961 ◽

Vol 175 (3) ◽

pp. 261

Author(s):

Milton Holiday Paul

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Natural History ◽

Atrial Septal Defect ◽

Congenital Heart ◽

Septal Defect ◽

History Of

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Never Too Old for Congenital Heart Disease: Sinus Venosus Atrial Septal Defect with Anomalous Pulmonary Venous Return in an Octogenarian

Pulmonary Circulation ◽

10.1086/682429 ◽

2015 ◽

Vol 5 (3) ◽

pp. 587-589

Author(s):

Ravi K. Sharma ◽

Brian A. Houston ◽

João A. C. Lima ◽

Duke E. Cameron ◽

Ryan J. Tedford

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Atrial Septal Defect ◽

Congenital Heart ◽

Septal Defect ◽

Venous Return ◽

Sinus Venosus ◽

Anomalous Pulmonary Venous Return

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Atrial septal defects (ASDs)

10.1093/med/9780199228188.003.0013 ◽

2011 ◽

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Atrial Septal Defect ◽

Coronary Sinus ◽

Patent Foramen Ovale ◽

Congenital Heart ◽

Septal Defect ◽

Foramen Ovale ◽

Septal Defects ◽

Different Types

Introduction 94Ostium secundum ASD 96Ostium primum ASD 100Sinus venosus ASD 100Coronary sinus defect 102Patent foramen ovale 104Interatrial communications account for ~10% of congenital heart disease. Different types of atrial septal defect (ASD) are illustrated in Fig. 8.1.•...

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Penanganan Perioperatif Pasien Penyakit Jantung Kongenital Dewasa dengan ASD, Suspek Hipertensi Pulmonal, LV Smallish

JAI (Jurnal Anestesiologi Indonesia) ◽

10.14710/jai.v9i2.19826 ◽

2017 ◽

Vol 9 (2) ◽

pp. 71

Author(s):

Wisnhu Wardhana ◽

Cindy Elfira Boom

Keyword(s):

Intensive Care Unit ◽

Congenital Heart Disease ◽

Intensive Care ◽

Heart Disease ◽

Atrial Septal Defect ◽

Patent Foramen Ovale ◽

Congenital Heart ◽

Septal Defect ◽

Foramen Ovale ◽

Asd Closure

Penyakit jantung kongenital dewasa / grown-up congenital heart disease (GUCH) yang menempati urutan teratas dengan insidensi 10% dari jantung kongenital asianotik pada dewasa adalah atrial septal defect (ASD). Terapi optimal ASD masih kontroversial. Operasi direkomendasikan pada pasien usia pertengahan dan usia tua dengan pintasan kiri ke kanan yang bermakna. Komorbid yang paling sering didapatkan pada defek kongenital pada usia dewasa muda adalah gangguan hemodinamik, hipertensi pulmonal, aritmia, penyakit kardiovaskular dan penyakit resprasi. Dilaporkan pasien perempuan usia 29 tahun dengan atrial septal defect(ASD) dengan hipertensi pulmonaldan Left Ventricle (LV) Smallishyang dilakukan operasi penututupan defek atrial atau ASD closure. Persiapan preoperasi mencakup anamnesa, pemeriksaan fisik dan pemeriksaan penunjang.Perubahan patologi utama adalah peningkatan resistensi vaskuler paru dan perubahan sekunder terhadap peningkatan aliran darah dari pintasan kiri ke kanan. Masalah yang dihadapi pada pasien perioperasi ini adalah ukuran jantung kiri baik atrium maupun ventrikel kiri yang kecil memberikan dampak hemodinamik tidak stabil berupa aritmia dan pulmonal hipertensi saat dilakukan penutupan defek. Pemberianobat topangan jantung (nitroglyserin, milrinone, norepinephrine, adrenaline) dan pembuatan Patent Foramen Ovale (PFO) memberikan hasil hemodinamik yang stabil selama operasi dan di ruang perawatan Intensive Care Unit (ICU).

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Pattern and frequency of pediatric congenital heart disease at the Cardiac Research Institute of Kabul Medical University, Afghanistan

Paediatrica Indonesiana ◽

10.14238/pi58.3.2018.106-9 ◽

2018 ◽

Vol 58 (3) ◽

pp. 106-9

Author(s):

Abdul Muhib Sharifi

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Atrial Septal Defect ◽

Tetralogy Of Fallot ◽

Congenital Heart ◽

Septal Defect ◽

Heart Defects ◽

Cardiac Lesions ◽

Medical University ◽

Research Institute

Background Congenital heart disease (CHD) is the most common birth defect, with incidence of 0.7-0.9 live birth; it increases to 2-6% if first degree relative is affected. In Afghanistan majority of births take place at home and routine screening of neonates is not common, so true birth prevalence of CHD cannot be possibly calculated. Therefore, true prevalence of CHD in our population is unknown. Objective To verify the current pattern and frequency distribution of congenital heart disease (CHD) at the Cardiac Research Institute of Kabul Medical University. Methods This retrospective study was conducted in children aged 0-14 years, who underwent echocardiography for possible congenital heart disease from January 2015 to December 2016. Results Of 560 patients who underwent echocardiography, 392(70%) had cardiac lesions. Congenital cardiac lesions were found in 235 (60% of those with lesions) patients, while 157 (40%) patients had rheumatic heart disease. Patients with CHD were further subdivided into acyanotic and cyanotic groups. The majority of acyanotic group had isolated atrial septal defect (55%) while the most common lesion in the cyanotic group was Tetralogy of Fallot (42%). Conclusion Congenital heart defects are the most common heart disease in the pediatric population presenting at the Cardiac Research Institute of Kabul Medical University. Atrial septal defect (ASD) was the most common acyanotic defect, while Tetralogy of Fallot (ToF) is the most common cyanotic defect.

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