scholarly journals High-sensitive Biomarkers of Blood Antiradical Activity in Mice Exposed to γ-irradiation

Author(s):  
S. Kalmakhelidz ◽  
T. Sanikidze ◽  
D. Topuria ◽  
I. Chkhikvishvili ◽  
E. Shekiladze ◽  
...  

Diagnostic markers are important indicators for the assessment of the possible consequences of radiation exposure, which could lead to acute and chronic radiation toxicity. The goal of the study is to determine high-sensitive markers of blood redox status in relation to the dose of radiation. The mice were exposed to γ-irradiation (Cs137) at a total dose of 3, 5, and 7Gy. After 1, 2, 7, and 14 days of the irradiation, the blood samples were drawn under ether anesthesia from the inferior vena cava and the activity of antioxidant system (enzymatic -superoxide dismutase (SOD), catalase) and non-enzymatic total antioxidant activity (TAA) of blood serum was determined. The results of our investigation support the fact that the non-enzymatic antioxidant TAA plays an important role in the prevention of radiation damage during ionizing radiation exposure, which makes it possible to consider TAA as a promising candidate as the biomarker of radiation dose.

Author(s):  
James Budge ◽  
Belen Quintana ◽  
Bijan Modarai ◽  
Alberto Smith ◽  
Prakash Saha ◽  
...  

2006 ◽  
Vol 175 (4S) ◽  
pp. 392-393
Author(s):  
Fernando P. Secin ◽  
Zohar A. Dotari ◽  
Bobby Shayegan ◽  
Semra Olgac ◽  
Bertrand Guillonneau ◽  
...  

VASA ◽  
1999 ◽  
Vol 28 (4) ◽  
pp. 289-292 ◽  
Author(s):  
Tiesenhausen ◽  
Amann ◽  
Thalhammer ◽  
Aschauer

Congenital anomalies of the caval vein are often associated with other abnormities such as heart defects, situs inversus or a polysplenia-asplenia-syndrome. An isolated, congenital malformation like aplasia of the inferior vena cava is a rare finding. A review of the embryology and abnormities, diagnostics, clinical signs and treatment is given together with the histories of two patients having thrombosis of the lower extremities and pelvic veins, caused by aplasia of the inferior vena cava. After thrombotic complications caused by vena cava aplasia there is high risk of recurrence. Those patients should be anticoagulated for lifetime.


VASA ◽  
2014 ◽  
Vol 43 (1) ◽  
pp. 73-77 ◽  
Author(s):  
Paweł Gać ◽  
Małgorzata Kuśmierska ◽  
Przemysław Jaźwiec ◽  
Magdalena Bolt ◽  
Anna Kuśmierska ◽  
...  

VASA ◽  
2011 ◽  
Vol 40 (2) ◽  
pp. 157-162 ◽  
Author(s):  
Piecuch ◽  
Wiewiora ◽  
Nowowiejska-Wiewiora ◽  
Szkodzinski ◽  
Polonski

The placement of an inferior vena cava (IVC) filter is a therapeutic method for selected patients with deep venous thrombosis and pulmonary embolism. However, insertion and placement of the filter may be associated with certain complications. For instance, retroperitoneal hematoma resulting from perforation of the wall by the filter is such a very rare but serious complication. We report the case of a 64-year-old woman with perforation of the IVC wall and consecutive hematoma caused by the filter who was treated surgically.


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