Dialysis Adequacy among Haemodialysis Patients in Eastern Mediterranean Region: A Systematic Review and Meta-Analysis

Abstract Background This study was conducted to provide evidence on the current status of breast cancer and its incidence trend in Eastern Mediterranean Region during 1998-2019. Also, this study aimed to investigate the association between the incidence of breast cancer and Human Development Index and some factors related to this index, including total fertility rate, and obesity, using a meta-analysis. Method Data on incidence of breast cancer were collected from various sources, including PubMed, Embase, Web of Science, and WHO, from 1998 to 2019 using systematic review and meta-analysis. Pooled age standardized rate was calculated based on study duration and quality of data using a subgroup analysis and random effect meta-analysis. Results A total of 80 studies (545 data points) were analyzed. Pooled age standardized rate of breast cancer for Eastern Mediterranean Region was 37.1 per 100 000 person-year (95% confidence interval [CI], 34.5, 39.8) during 2011-2019. age standardized rate of breast cancer had an upward trend in Eastern Mediterranean Region from 2005 to 2019. However, the increasing trend was found to be slightly different in various regions based on quality of data. Moreover, pooled age standardized rate had a significant association with Human Development Index [-89.2 (95% CI, -119.8, -58.7)] and obesity [1.2 (95% CI, 0.9, 1.5)]. Conclusion Pooled age standardized rate of breast cancer in Eastern Mediterranean Region was lower than the global average. Also, the age standardized rate value and its incremental trend have been higher in countries with high-quality data than in other countries of this region in recent years. Data quality or physiological factors, such as increase in obesity rates, could be the reasons for this incremental trend.

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Incidence Trend of Breast Cancer in Women of Eastern Mediterranean Region countries from 1998 to 2019: A Systematic Review and Meta-Analysis

10.21203/rs.2.13816/v4 ◽

2020 ◽

Author(s):

Razieh Zahedi ◽

Hossein Molavi Vardanjani ◽

Mohammad Reza Baneshi ◽

Ali Akbar Haghdoost ◽

Reza Malekpour Afshar ◽

...

Keyword(s):

Breast Cancer ◽

Systematic Review ◽

Human Development ◽

Human Development Index ◽

Mediterranean Region ◽

Eastern Mediterranean ◽

Meta Analysis ◽

Eastern Mediterranean Region ◽

Quality Of Data

Abstract Background This study was conducted to provide evidence on the current status of breast cancer and its incidence trend in Eastern Mediterranean Region during 1998-2019. Also, this study aimed to investigate the association between the incidence of breast cancer and Human Development Index and some factors related to this index, including total fertility rate, and obesity, using a meta-analysis. Method Data on incidence of breast cancer were collected from various sources, including PubMed, Embase, Web of Science, and WHO, from 1998 to 2019 using systematic review and meta-analysis. Pooled age standardized rate was calculated based on study duration and quality of data using a subgroup analysis and random effect meta-analysis. Results A total of 80 studies (545 data points) were analyzed. Pooled age standardized rate of breast cancer for Eastern Mediterranean Region was 37.1 per 100 000 person-year (95% confidence interval [CI], 34.5, 39.8) during 2011-2019. age standardized rate of breast cancer had an upward trend in Eastern Mediterranean Region from 2005 to 2019. However, the increasing trend was found to be slightly different in various regions based on quality of data. Moreover, pooled age standardized rate had a significant association with Human Development Index [-89.2 (95% CI, -119.8, -58.7)] and obesity [1.2 (95% CI, 0.9, 1.5)]. Conclusion Pooled age standardized rate of breast cancer in Eastern Mediterranean Region was lower than the global average. Also, the age standardized rate value and its incremental trend have been higher in countries with high-quality data than in other countries of this region in recent years. Data quality or physiological factors, such as increase in obesity rates, could be the reasons for this incremental trend. Key words Breast cancer, meta-analysis, Eastern Mediterranean region, Incidence

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Posttraumatic Stress in Adult Civilians Exposed to Violent Conflict, War and Associated Human Rights Abuses in the Eastern Mediterranean Region: A Systematic Review and Meta-Analysis

Journal of Affective Disorders ◽

10.1016/j.jad.2021.06.042 ◽

2021 ◽

Author(s):

Jana Stein ◽

Helen Niemeyer ◽

Caroline Meyer ◽

Christina Wirz ◽

Anna Eiling ◽

...

Keyword(s):

Systematic Review ◽

Human Rights ◽

Posttraumatic Stress ◽

Mediterranean Region ◽

Eastern Mediterranean ◽

Meta Analysis ◽

Eastern Mediterranean Region ◽

Violent Conflict ◽

Human Rights Abuses

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Self-medication with antibiotics in WHO Eastern Mediterranean Region: A Systematic Review and Meta-analysis

10.21203/rs.3.rs-39213/v1 ◽

2020 ◽

Author(s):

Reza Negarandeh ◽

Shah Jahan Shayan ◽

Rajab Nazari ◽

BSc. Frank Kiwanuka ◽

MSc. Sanaz Akhavan Rad

Keyword(s):

Systematic Review ◽

Mediterranean Region ◽

Respiratory Infections ◽

Eastern Mediterranean ◽

Meta Analysis ◽

Eastern Mediterranean Region ◽

World Health ◽

Common Source ◽

Self Medication ◽

Inappropriate Use

Abstract Background Recently, inappropriate use of antibiotics has been correlated with life-threatening side-effects such as adverse effects, increased cost of treatment, and the higher rate of microbial resistance. Besides, it leads to a waste of resources. Therefore, this review sought to determine the pooled prevalence of self-medication with antibiotics, self-medicated illness, reasons for self-medication, antibiotics used for self-medication, source of obtaining antibiotics, the inappropriate practice of antibiotics and suggested recommendations for talking self-medication with antibiotics in the Eastern Mediterranean Region of the World Health Organization (EMRWHO). Methods Review conforms to the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) statement. Database search was conducted in PubMed, Scopus, Embase, and Web of Science using a combination of keywords which included; antimicrobial, antibacterial, antibiotic, self-medication, self-treatment, self-prescription, non-prescribed, irrational use, inappropriate use, misuse, abuse and Eastern Mediterranean Region of WHO countries. The lists of references of the selected articles were also hand-searched to obtained additional relevant articles. Studies published in English from 2000 to 2018 were included in the review. Results We report on data from 60 articles and 49629 participants in this review. The overall prevalence of self-medication with antibiotics in EMRWHO was 47.2% (95% CI 41.6% – 52.9%). Yemen has the highest pooled rate with a rate of 75.0% (95% CI 63.4% − 83.9%), whilst Lebanon has the lowest pooled rate with a prevalence of 28.7% (95% CI 18.4% − 41.8%). The most common illnesses implicated in antibiotic self-medication were upper-respiratory infections and the most common antibiotic was Amoxicillin-Clavulanic acid. The commonest reasons for antibiotic self-medication include: saving time and money. Pharmacies pointed out as the most common source of obtaining antibiotics for self-medication. Conclusion Self-medication with antibiotics is significantly high in the member states of EMRWHO. Intervention such as an educational program for communities’ members to change their behaviors, policy on the mechanism of distribution of antibiotics is called for in this area.

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