SURGICAL TREATMENT OF NECROTIZING ENTEROCOLITIS MULTIFOCAL FORMSIN PREMATURE INFANTS – CLIP AND DROP TECHNIQUE

2017 ◽  
Vol 96 (4) ◽  
pp. 116-120
Author(s):  
Y. A. Kozlov ◽  
◽  
V. A. Novozhilov ◽  
I. N. Weber ◽  
A. A. Rasputin ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Necrotizing Enterocolitis ◽  
Premature Infants ◽  
Drop Technique

Perioperative Complications Following Surgery for Necrotizing Enterocolitis

2018 ◽  
Vol 28 (02) ◽  
pp. 148-151 ◽  
Author(s):  
Annika Mutanen ◽  
Agostino Pierro ◽  
Augusto Zani
Keyword(s):  
Surgical Treatment ◽  
Necrotizing Enterocolitis ◽  
Premature Infants ◽  
Perioperative Complications ◽  
Neurodevelopmental Outcome ◽  
Wound Infections ◽  
Perioperative Morbidity

AbstractNecrotizing enterocolitis (NEC) is a devastating condition that mainly affects premature infants. Advanced cases of NEC require surgical treatment, which in up to 70% of infants is associated with significant perioperative morbidity including anastomosis- or enterostomy-related complications, sepsis, peritonitis, and wound infections. Moreover, the perioperative complications may compromise the long-term gastrointestinal and neurodevelopmental outcome of patients requiring surgery for NEC.

SURGICAL TREATMENT OF NECROTIZING ENTEROCOLITIS IN PREMATURE INFANTS – MULTILEVEL COMPARISON RESULTS

2018 ◽  
Vol 97 (1) ◽  
pp. 88-95
Author(s):  
Y.A. Kozlov ◽  
◽  
V.A. Novozhilov ◽  
K.A. Kovalkov ◽  
D.M. Chubko ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Necrotizing Enterocolitis ◽  
Premature Infants ◽  
Comparison Results

scholarly journals Predictive factors for the surgical treatment of necrotizing enterocolitis in preterm infants: a single-center retrospective study

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Yusheng Liu ◽  
Lingyan Qiao ◽  
Xiongwei Wu ◽  
Zhong Jiang ◽  
Xiwei Hao
Keyword(s):  
Surgical Treatment ◽  
Preterm Infants ◽  
Necrotizing Enterocolitis ◽  
Premature Infants ◽  
Multivariate Analyses ◽  
Gastrointestinal Disease ◽  
Ductus Arteriosus ◽  
Clinical Manifestations ◽  
Serum Bicarbonate ◽  
Early Occurrence

Abstract Background Necrotizing enterocolitis (NEC) is a gastrointestinal disease that tends to occur in premature infants. Some features may be associated with an increased probability that preterm infants with NEC will require surgical treatment. This study aimed to identify the factors that increased the probability of surgical treatment in infants with NEC. Methods We retrospectively analyzed the data of premature infants with NEC who were hospitalized at The Affiliated Hospital of Qingdao University from April 2011 to April 2021. According to the treatments received, these patients were divided into medical NEC group and surgical NEC group. The perinatal characteristics, clinical manifestations, and laboratory values before the onset of NEC were subjected to univariate and multivariate analyses. Results A total of 623 preterm infants with NEC (> Bell’s stage I) were included in this study, including 350 (56%) who received surgical treatment and 273 (44%) who received conservative medical treatment. Multivariate analysis showed that lower gestational age (P = 0.001, odds ratio (OR) (95% CI) = 0.91[0.86–0.96]), early occurrence of NEC (P = 0.003, OR (95% CI) = 0.86 [0.77–0.95]), hemodynamically significant patent ductus arteriosus (P = 0.003, OR (95% CI) = 7.50 [2.03–28.47]), and low serum bicarbonate (P = 0.043, OR (95% CI) = 0.863 [0.749–0.995]) were associated with an increased probability of surgical treatment in preterm infants with NEC. Conclusions Our findings were applied to identify potential predictors for surgical treatment in preterm infants with NEC, which may facilitate early decisive management.

Outcomes of the “clip and drop” technique for multifocal necrotizing enterocolitis

2009 ◽  
Vol 44 (4) ◽  
pp. 749-754 ◽  
Author(s):  
Ori Ron ◽  
Mark Davenport ◽  
Shailesh Patel ◽  
Edward Kiely ◽  
Agostino Pierro ◽  
...  
Keyword(s):  
Necrotizing Enterocolitis ◽  
Drop Technique

Carbohydrate Malabsorption in Necrotizing Enterocolitis

PEDIATRICS ◽  
1976 ◽  
Vol 57 (2) ◽  
pp. 201-204
Author(s):  
Linda Sue Book ◽  
John J. Herbst ◽  
August L. Jung
Keyword(s):  
Necrotizing Enterocolitis ◽  
Premature Infants ◽  
Clinical Symptoms ◽  
Advanced Disease ◽  
Full Term ◽  
Term Infants ◽  
Stool Specimens ◽  
Reducing Substances ◽  
Carbohydrate Intolerance ◽  
Prospective Investigation

A prospective investigation was conducted to determine if infants with necrotizing enterocolitis had evidence of carbohydrate intolerance prior to the onset of clinical symptoms of advanced disease. Stool specimens were examined for fecal reducing substances with Clintest tablets from well, full-term infants and sick premature infants. Only two of 45 (4.4%) formula-fed, full-term infants demonstrated higher than 2 + fecal reducing substances. Ten of 14 (71%) formula-fed premature infants who developed necrotizing enterocolitis had higher than 2 + reducing substances detected in their stools. Daily measurement of fecal reducing substances can be a useful adjunct in the management of sick premature infants.

scholarly journals Influence of Family Integrated Care on the Intestinal Microbiome of Preterm Infants With Necrotizing Enterocolitis and Enterostomy: A Preliminary Study

2021 ◽  
Vol 9 ◽  
Author(s):  
Mengyang Yang ◽  
Juan Du ◽  
Qin Yang ◽  
Wenyan Dou ◽  
Min Jiang ◽  
...  
Keyword(s):  
Integrated Care ◽  
Preterm Infants ◽  
Necrotizing Enterocolitis ◽  
Premature Infants ◽  
Intestinal Flora ◽  
Intestinal Microbiome ◽  
Rrna Gene ◽  
Α Diversity ◽  
Family Integrated Care ◽  
Family Integrated

The aim of this study was to investigate the influence of family integrated care (FICare) on the intestinal microbiome of preterm infants with necrotizing enterocolitis and enterostomy. This was a prospective pilot study at Beijing Children's Hospital. Premature infants with an enterostomy who met the enrollment criteria were divided into the 2-week FICare and non-FICare groups (non-randomly). We collected their fecal samples and subjected the intestinal microbiomes to 16S rRNA gene sequencing. Operational taxonomic units (OTU) were analyzed to assess the intestinal microbiome richness, and we then carried out α-diversity, β-diversity, and species clustering analyses and a linear discriminant analysis (LDA) effect size (LEfSe) analysis to identify the differences in the microbial communities between the two groups. There were 12 patients enrolled in the study (FICare, n = 7; non-FICare, n = 5). There were no significant between-group differences in demographic characteristics, or in the relative abundances of phyla and genera. The major bacterial phyla were Proteobacteria, Firmicutes, and Actinobacteria, and Serratia, Enterococcus, Cronobacter, and Bifidobacterium dominated at the genus level. The α-diversity analysis indicated that the intestinal flora was more diverse in the non-FICare group than the FICare group (p < 0.05). However, most of the other indicators did not suggest a difference between the two groups. There was a high proportion of shared OTUs between the two groups, and the PCoA and clustering analyses indicated that the two groups were difficult to distinguish, indicating that the intestinal microbiomes were relatively similar between the groups. In summary, short-term FICare had no significant positive effect on the establishment of intestinal flora diversity in premature infants with necrotizing enterocolitis and enterostomy. The trial was registered in the Chinese Clinical Trial Registry (ChiCTR-OPN-17011801).

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