Bone marrow cell morphology in congenital diserythropoietic anemia: selective enrichment of the studied cell population for light and electron microscopy using a microarray and centrifugation in a density gradient

2018 ◽  
Vol 17 (1) ◽  
pp. 104-107
Author(s):  
S.I. Obydennyi ◽  
◽  
O.S. Fedyanina ◽  
A.N. Khvastunova ◽  
A.O. Zakirova ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Bone Marrow ◽  
Density Gradient ◽  
Cell Population ◽  
Bone Marrow Cell ◽  
Cell Morphology ◽  
Marrow Cell ◽  
Light And Electron Microscopy ◽  
Selective Enrichment

scholarly journals AML, ALL, and CML classification and diagnosis based on bone marrow cell morphology combined with convolutional neural network

Medicine ◽  
2020 ◽  
Vol 99 (45) ◽  
pp. e23154
Author(s):  
Furong Huang ◽  
Peiwen Guang ◽  
Fucui Li ◽  
Xuewen Liu ◽  
Weimin Zhang ◽  
...  
Keyword(s):  
Neural Network ◽  
Bone Marrow ◽  
Convolutional Neural Network ◽  
Bone Marrow Cell ◽  
Cell Morphology ◽  
Marrow Cell

scholarly journals Diagnostic Value of Bone Marrow Cell Morphology in Visceral Leishmaniasis-Associated Hemophagocytic Syndrome of Two Cases

2021 ◽  
Author(s):  
SHULAN SHI ◽  
HENG ZHAO ◽  
MINGBIAO MA ◽  
XIAOJUAN LI ◽  
JI XU ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Visceral Leishmaniasis ◽  
Bone Marrow Cell ◽  
Cell Morphology ◽  
Hemophagocytic Syndrome ◽  
Bone Marrow Cells ◽  
Marrow Cell ◽  
Morphological Examination ◽  
Children's Hospital ◽  
Marrow Cells

Abstract Background: Visceral leishmaniasis related-hemophagocytic lymphohistiocytosis (VL-HLH) is a hemophagocytic syndrome caused by Leishmania infection. VL-HLH is rare, especially in nonendemic areas where the disease is severe, and mortality rates are high. The key to diagnosing VL-HLH is to find the pathogen; therefore, the Leishmania must be accurately identified for timely clinical treatment.Case presentationWe retrospectively analyzed the clinical data, laboratory examination results and bone marrow cell morphology of two children with VL-HLH diagnosed via bone marrow cell morphology between July 2017 and January 2021 at Kunming Children’s Hospital of Yunnan, China.Two cases suspected of having malignant tumors at other hospitals and who had undergone ineffective long-term treatment were transferred to Kunming Children’s Hospital. They had repeated fevers, pancytopenia, hepatosplenomegaly, hypertriglyceridemia, and hypofibrinogenemia over a long period and met the HLH-2004 standard. Their HLH genetic test results were negative, and primary HLH was excluded. Both children underwent chemotherapy as per the HLH-2004 chemotherapy regimen , but it was ineffective and accompanied by serious infections. We found Leishmania amastigotes in their bone marrow via morphological examination of their bone marrow cells, which showed hemophagocytic cells; thus, the children were diagnosed with VL-HLH. After being transferred to a specialty hospital for treatment, the condition was well-controlled. Conclusion: Morphological examination of the bone marrow cells played an important role in diagnosing VL-HLH. When clinically diagnosing secondary HLH, VL-HLH should be considered in addition to common pathogens, especially in patients for whom HLH-2004 chemotherapy regimens are ineffective. For infants and young children, bone marrow cytology examinations should be performed several times and as early as possible to find the pathogens to reduce potential misdiagnoses.

Osteoclast Progenitors Reside in PPARγ-Expressing Bone Marrow Cell Population

2011 ◽  
pp. P1-23-P1-23
Author(s):  
Yihong Wan ◽  
Wei Wei ◽  
Daniel Zeve ◽  
Xueqian Wang ◽  
Yang Du ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Cell Population ◽  
Bone Marrow Cell ◽  
Marrow Cell

The significance of bone marrow cell morphology and its correlation with cytogenetic features in the diagnosis of MDS-RA patients

2009 ◽  
Vol 33 (8) ◽  
pp. 1029-1038 ◽  
Author(s):  
Dandan Liu ◽  
Zixing Chen ◽  
Yongquan Xue ◽  
Dingwei Lu ◽  
Youning Zhou ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Cell ◽  
Cell Morphology ◽  
Marrow Cell

Retrospective evaluation of bone marrow cell morphology in a cohort of patients with isolated idic(20q-) karyotypic abnormalities

2018 ◽  
Vol 98 (3) ◽  
pp. 605-614
Author(s):  
Dandan Liu ◽  
Jinlan Pan ◽  
Chunxiao Wu ◽  
Jianying Liang ◽  
Jingjing Wang ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Cell ◽  
Cell Morphology ◽  
Marrow Cell ◽  
Retrospective Evaluation

Osteoclast progenitors reside in ppar-gamma-expressing bone marrow cell population

Bone ◽  
2011 ◽  
Vol 48 ◽  
pp. S97
Author(s):  
Y. Wan ◽  
W. Wei ◽  
D. Zeve ◽  
X. Wang ◽  
Y. Du ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Cell Population ◽  
Bone Marrow Cell ◽  
Marrow Cell ◽  
Ppar Gamma
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