Quantitative in vivo measurement of central benzodiazepine receptors in the brain of cats by use of positron-emission tomography and [11C]flumazenil

2003 ◽  
Vol 64 (8) ◽  
pp. 999-1002
Author(s):  
Yuhei Shimada ◽  
Motohiro Kiyosawa ◽  
Tadashi Nariai ◽  
Keiichi Oda ◽  
Hinako Toyama ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Benzodiazepine Receptors ◽  
Emission Tomography ◽  
In Vivo Measurement ◽  
Positron Emission ◽  
Central Benzodiazepine Receptors ◽  
The Brain

scholarly journals In vivo Measurement of Regional Cerebral Haematocrit Using Positron Emission Tomography

1984 ◽  
Vol 4 (3) ◽  
pp. 317-322 ◽  
Author(s):  
Adriaan A. Lammertsma ◽  
David J. Brooks ◽  
Ronald P. Beaney ◽  
David R. Turton ◽  
Malcolm J. Kensett ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Blood Volume ◽  
Cerebral Blood Volume ◽  
Mean Value ◽  
Emission Tomography ◽  
Regional Cerebral Blood ◽  
In Vivo Measurement ◽  
Positron Emission ◽  
Regional Cerebral Blood Volume

A method is described for measuring the regional cerebral-to-large vessel haematocrit ratio using inhalation of carbon-11-labelled carbon monoxide and the intravenous injection of carbon-11-labelled methyl-albumin in combination with positron emission tomography. The mean value in a series of nine subjects was 0.69. This is ∼20% lower than the value of 0.85 previously reported. It is concluded that previous measurements of regional cerebral blood volume using a haematocrit ratio of 0.85 will have underestimated the value of regional cerebral blood volume by 20%.

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