scholarly journals Hand, Foot and Mouth Disease in Immunocompetent Adult with Severe Oral Manifestation

2020 ◽  
Vol 12 (3) ◽  
pp. 87-91
Author(s):  
Sulasmia ◽  
Khairuddin Djawad ◽  
Grace S. Lauren
Keyword(s):  
Enterovirus 71 ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Immunocompetent Adult ◽  
Symptomatic Infection ◽  
Oral Manifestation ◽  
Mild Disease ◽  
Hand Foot Mouth Disease ◽  
Hands And Feet ◽  
Immunocompetent Adults

Abstract Hand-foot-mouth Disease (HFMD) is an acute, self-limited, and highly contagious disease caused by a virus and generally affects children under 10 years old. The etiology of this disease is enterovirus 71 or coxsackievirus A16 which usually causes symptomatic infection or mild disease. Immunocompetent adults are rarely affected. However, recently the incidence of HFMD in immunocompetent adults has increased. We report a 41-year-old woman with severe oral lesions and painful papulovesicular eruption on the palms of her hands and feet.

scholarly journals Detection of hand, foot and mouth disease in the Yucatan Peninsula of Mexico

2014 ◽  
Vol 6 (4) ◽  
Author(s):  
Carlos Machain-Williams ◽  
Alma R. Dzul-Rosado ◽  
Aarón B. Yeh-Gorocica ◽  
Katia G. Rodriguez-Ruz ◽  
Henry Noh-Pech ◽  
...  
Keyword(s):  
Yucatan Peninsula ◽  
Enterovirus 71 ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Nucleotide Sequencing ◽  
Yucatán Peninsula ◽  
Pubmed Database ◽  
Foot And Mouth ◽  
Polymerase Chain ◽  
Hands And Feet

We report a case of hand, foot and mouth disease (HFMD) in a 5-year-old male from Merida City in the Yucatan Peninsula of Mexico. A clinical and physical examination revealed that the patient had symptoms typical of HFMD, including fever, fatigue, odynophagia, throat edema, hyperemia, lesions on the hands and feet, and blisters in the oral cavity. The patient fully recovered after a convalescence period of almost three weeks. Reverse transcription-polymerase chain reaction and nucleotide sequencing revealed that the etiological agent was enterovirus 71 (EV71). The sequence has greatest (90.4%) nucleotide identity to the corresponding regions of EV71 isolates from the Netherlands and Singapore. Although HFMD is presumably common in Mexico, surprisingly there are no data in the PubMed database to support this. This case report provides the first peer-reviewed evidence of HFMD in Mexico.

scholarly journals Onychomadesis associated with hand, foot, and mouth disease: a prospective observational study from North Chennai

2020 ◽  
Vol 6 (3) ◽  
pp. 367
Author(s):  
Saraswathy Pichaachari ◽  
Jayanthi Nagappan Subramaniam ◽  
Sajeetha Sundaram
Keyword(s):  
Clinical Diagnosis ◽  
Enterovirus 71 ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Human Enterovirus ◽  
Time Interval ◽  
Benign Condition ◽  
Human Enterovirus 71 ◽  
Foot And Mouth ◽  
Hands And Feet

<p class="abstract"><strong>Background:</strong> Hand, foot, and mouth disease (HFMD) is a common febrile illness caused by coxsackievirus A16 and human enterovirus 71 characterized by vesicular eruptions on hands and feet and enanthem on oral mucosa. Resolves usually without complications but onychomadesis can occur as a late sequlae sometimes.</p><p class="abstract"><strong>Methods:</strong> Children with clinical diagnosis of HFMD between April to June 2018 were included in the study. Age, sex, duration of illness, cutaneous features and nail changes were noted at initial visit and during every week for next 6 weeks.<strong></strong></p><p class="abstract"><strong>Results:</strong> 58 children were recruited in the study with boys to girl’s ratio 1.2:1. The average age was 5.3 years. The vesicular lesions predominantly involved palms and soles (88.3%). 65.5% had history of fever and pruritis was the commonest cutaneous symptom. 27 children (48.21%) developed onychomadesis during follow up with average time interval of 3.2 weeks between the clinical diagnosis and nail shedding. Reassurance about spontaneous resolution of the condition given to the parents.</p><p class="abstract"><strong>Conclusions:</strong> Our study strengthened the association between the HFMD and occurrence of onychomadesis. Physician’s awareness about this benign condition is needed to avoid parental anxiety, unnecessary investigations and treatment for the children.   </p>

scholarly journals Study the current scenario of hand foot mouth disease an Indian prospective

2020 ◽  
Vol 7 (7) ◽  
pp. 1558
Author(s):  
Ravi Sahota ◽  
Navpreet Kaur ◽  
Gurpal Singh ◽  
Nisha Upadhyay
Keyword(s):  
Communicable Disease ◽  
Enterovirus 71 ◽  
Foot And Mouth Disease ◽  
Neurological Complications ◽  
Mouth Disease ◽  
Human Enterovirus ◽  
Cross Sectional ◽  
Timely Initiation ◽  
Human Enterovirus 71 ◽  
Hand Foot Mouth Disease

Background: The hand-foot-mouth disease (HFMD) is an acute communicable disease, mostly affecting children under 5 years of age and caused by human enterovirus 71 (EV-A71) and coxsackievirus A16 (CV-A16). The usual incubation period is 3 to 7 days. Early symptoms are likely to be fever often followed by a sore throat followed by loss of appetite and general malaise. Aim and objectives was to study the trend of hand foot and mouth disease in a private hospital in Uttarakhand over 5 successive years.Methods: This cross-sectional study was carried among 297 cases of HFMD newborn screened at pediatrics department of Sahota Super-specialty hospital, Kashipur, Uttarakhand during year 2015 to 2019 after ethical clearance of institutional ethical committee. Diagnosis is coded with ICD-10. SPSS version 20 was used to calculate frequencies and percentiles.Results: Almost 29 cases of HMFD were picked in 2015, 32 cases in 2016, 43 cases in 2017, 81 cases in 2018, 112 in 2019. Fever observed in 86% cases. Neurological complications were observed in 9 (3%) cases, pneumonitis in 14 (4.7%) cases, cardiomyopathy observed in 3 (<1%) case. One death was reported.Conclusions: It is vital to screen patients with HFMD for these abnormal clinical presentations, allowing timely initiation of appropriate interventions to reduce the mortality. Increased awareness about vaccination in a developing nation like India and vaccination program at the grass root levels have eradicated certain lethal diseases.

scholarly journals Hand, Foot and Mouth Disease (HFMD): An Update

2017 ◽  
Vol 40 (2) ◽  
pp. 115-119 ◽  
Author(s):  
Probir Kumar Sarkar ◽  
Nital Kumar Sarker ◽  
Md Abu Tayab
Keyword(s):  
Enterovirus 71 ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Coxsackie Virus ◽  
Asia Pacific ◽  
Human Enterovirus ◽  
Small Scale ◽  
Human Enterovirus 71 ◽  
Mild Disease ◽  
Foot And Mouth

Hand, foot, and mouth disease (HFMD) also known as vesicular stomatitis with exanthema, first reported in New Zealand in 1957 is caused by Coxsackie virus A16 (CVA16), human enterovirus 71 (HEV71) and occasionally by other HEV-A serotypes, such as Coxsackie virus A6 and Coxsackie virus A10, are also associated with HFMD and herpangina. While all these viruses can cause mild disease in children, EV71 has been associated with neurological disease and mortality in large outbreaks in the Asia Pacific region over the last decade. It is highly contagious and is spread through direct contact with the mucus, saliva, or feces of an infected person. This is characterized by erythrematous papulo vesicular eruptions over hand, feet, perioral area, knee, buttocks and also intra-orally mostly in children, typically occurs in small epidemics usually during the summer and autumn months. HFMD symptoms are usually mild and resolve on their own in 7 to 10 days. Treatment is symptomatic but good hygiene during and after infection is very important in preventing the spread of the disease. Though only small scale outbreaks have been reported from United States, Europe, Australia Japan and Brazil for the first few decade, since 1997 the disease has conspicuously changed its behavior as noted in different Southeast Asian countries. There was sharp rise in incidence, severity, complications and even fatal outcomes that were almost unseen before that period. There are reports of disease activity in different corners of India since 2004, and the largest outbreak of HFMD occurred in eastern part of India in and around Kolkata in 2007and Bhubaneswar, Odisha in 2009. In recent years there are cases of HFMD have been seen in Bangladesh also. Although of milder degree, continuous progress to affect larger parts of the neighboring may indicate vulnerability of Bangladesh from possible future outbreaks.Bangladesh J Child Health 2016; VOL 40 (2) :115-119

scholarly journals A Case of Hand-Foot-Mouth Disease observed during Routine Dental Checkup in an Immunocompetent Healthy Adult Patient

2017 ◽  
Vol 8 (1) ◽  
pp. 42-45
Author(s):  
Poorna Devadoss, ◽  
Skanda Ramesh, ◽  
Pradeep Christopher, ◽  
Anbu Velusamy
Keyword(s):  
Adult Patient ◽  
Hard Palate ◽  
Healthy Adult ◽  
Enterovirus 71 ◽  
Mouth Disease ◽  
Coxsackie Virus ◽  
Oral Lesions ◽  
Immunocompetent Adult ◽  
Patient Reported ◽  
Hand Foot Mouth Disease

ABSTRACT Signs of oral lesions are one of the initial indications for many major diseases. As we come across different lesions during routine dental checkups, we should be aware about the diseases associated with those lesions. A 47-year-old immunocompetent adult patient reported with small erythematous lesions in the hard palate and small ulcers in the tonsillar pillars and right buccal mucosa with mild pyrexia of 37.8°C. Maculopapular lesions were found on the palms and soles. He was diagnosed with hand-foot-mouth disease, which is caused by the following viruses: Enterovirus-71, Coxsackie Virus (CV)-16, CV-A6, and CV-A10. The severity of this condition leads to meningitis, paralytic polio, and onychomadesis (falling of nails). How to cite this article Devadoss P, Ramesh S, Christopher P, Velusamy A. A Case of Hand-Foot-Mouth Disease observed during Routine Dental Checkup in an Immunocompetent Healthy Adult Patient. J Health Sci Res 2017;8(1):42-45.

scholarly journals Hand, Foot and Mouth Disease: A case report

2017 ◽  
Vol 4 (1) ◽  
pp. 59-64
Author(s):  
Vikash K Sah
Keyword(s):  
Case Report ◽  
Enterovirus 71 ◽  
Foot And Mouth Disease ◽  
Outpatient Setting ◽  
Severe Form ◽  
Mouth Disease ◽  
Coxsackie Virus ◽  
Medical College ◽  
Mild Disease ◽  
Fatal Form

Hand, foot & mouth disease (HFMD) is a common emerging infectious disease caused by intestinal viruses of the picornaviridae family. A strain of Coxsackie virus (A16, A5, A6) is chiefly instrumental for producing this condition however more severe form is caused by Enterovirus-71. Though HFMD is a mild disease and can often be effectively and competently managed in an outpatient setting, recent outbreaks in the western pacific region with fatal form of disease have attracted the concern about the clinical assessment and appropriate management of HFMD. Early detection and good clinical judgments not only can prevent the fatal progression but also can reduce overall morbidity and mortality regarding HFMD. I am presenting a case report of the afore mentioned disease and the subsequent early clinical manifestation of the fatal form of HFMD to enlighten on the nature of the disease so that early diagnosis and management of the condition can be carried out to halt the disease progression and prevention for the betterment of children especially under five years.Janaki Medical College Journal of Medical Sciences (2016) Vol. 4 (1): 59-64

scholarly journals Hand Foot and Mouth Disease (HFMD) in a 3 Years Old Boy in Bangladesh: A Case Report

2020 ◽  
Vol 6 (2) ◽  
pp. 53-55
Author(s):  
Arifa Akram ◽  
Lubana Akram
Keyword(s):  
Enterovirus 71 ◽  
Foot And Mouth Disease ◽  
Neurological Complications ◽  
Mouth Disease ◽  
Coxsackie Virus ◽  
Human Enterovirus ◽  
Small Scale ◽  
Asian Countries ◽  
Human Enterovirus 71 ◽  
Mild Disease

Hand, foot & mouth disease (HFMD) is a contagious and emerging infectious disease caused by picorna viridae family. It was first reported in New Zealand in 1957 is caused by Coxsackie virus A16 (CVA16), human enterovirus 71 (HEV71) and occasionally by Coxsackie virus A6 and Coxsackie virus A10, are also associated with HFMD and herpangina. Though only small scale outbreaks have been reported from United States, Europe, Australia Japan and Brazil for the first few decades, since 1997 the disease has noticeably changed its character as noted in different Southeast Asian countries. In recent years Bangladesh also faces some cases of HFMD. Though HFMD is a mild disease but in rare cases may develop neurological complications. Early detection and good clinical assessment can prevent the fatal progression and also can reduce morbidity and mortality regarding HFMD. Bangladesh Journal of Infectious Diseases 2019;6(2):53-55

HAND, FOOT AND MOUTH DISEASE IN SOUTH BENGAL AND KOLKATA: A STUDY OVER 5 YEARS TO EVALUATE CASES WITH CLINICAL SUSPICION

2021 ◽  
pp. 39-41
Author(s):  
Swagnik Roy ◽  
Bibhas SahaDalal ◽  
Rajat Dasgupta ◽  
Sourabh Mitra ◽  
Amrita Roy ◽  
...  
Keyword(s):  
Disease Risk ◽  
Enterovirus 71 ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Ev71 Infection ◽  
Human Enterovirus ◽  
Neurological Involvement ◽  
Neurogenic Pulmonary Edema ◽  
Foot And Mouth ◽  
Hands And Feet

Hand, foot, and mouth disease is a very infective infection. It's caused by viruses from the Enterovirus genus, among the Enterovirus genus coxsackievirus is most commonly found associated with Hand , Foot and Mouth disease. Hand, foot and mouth disease (HFMD) causes rashes or vesicular lesions in the affected individuals and lesions are found in extremities and upper extremity lesion is more common along with feet and mouth. It is mostly seen in school going children, and causative agents are likely Enterovirus-A (EV-A) species, including Coxsackievirus-A16 (CV-A16) and Enterovirus-71 (EV-71) [1]. Hand , Foot and Mouth Disease is usullay mild and selimiting. In the affected patient's rst identied by a brief prodromal fever, followed by pharyngitis, mouth ulcers and rash on the hands and feet. The disease is caused by numerous members of the Enterovirus genus of the family Picornaviridae e.g. Coxsackievirus type A (CA) and Enterovirus 71 (EV71), and the clinical features are not identiable and distinguishable from virus to virus. [2] . Young children have the highest risk of getting hand, foot, and mouth disease. Risk increases if they attend daycare or school, as viruses can spread quickly in these facilities. Children usually build up immunity to the disease after being exposed to the viruses that cause it. This is why the condition rarely affects people over age 10. However, it's still possible for older children and adults to get the infection, especially if they have weakened immune systems. EV71 is a human enterovirus A species causing infection in clildren[3,4] . Clinically though it is mild symptoms and self limiting initially, such as a fever along with unraised colorless spots, and bumps on the hands, feet, and mouth. In some patients with severe disease several neurological complications (including cephalomeningitis, encephalitis, and neurogenic pneumonedema) and circulatory disorders. Occasionally, it even causes death [5]. Therefore, an early indicator of EV71 infection with neurological involvement is crucial for appropriate management [6]. Hand, foot, and mouth disease by enterovirus infection repots severe complications (such as brain stem encephalitis, neurogenic pulmonary edema, and other fatal complications) and a high mortality due to HFMD are more frequently related to EV71 infection[7,8] .

scholarly journals The different symptoms determining management of hand foot and mouth disease and primary varicella zoster infection

2019 ◽  
Vol 52 (1) ◽  
pp. 32
Author(s):  
Maharani Laillyza Apriasari
Keyword(s):  
Clinical Manifestations ◽  
Enterovirus 71 ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
The Body ◽  
Upper Lip ◽  
Varicella Zoster ◽  
Foot And Mouth ◽  
Hands And Feet ◽  
Varicella Zoster Infection

Background: Hand, foot and mouth disease (HFMD) is a medical condition endemic among children in South-East Asia, including Indonesia and, more specifically, Banjarmasin – the capital of South Sulawesi. The disease is mediated by Enterovirus 71 and Coxsackievirus 16 which attack the oral cavity, hands, feet, buttocks and genital areas. One differential diagnosis of this disease is Primary Varicella Zoster infection. Both diseases have similar clinical symptoms but different etiologies which can precipitate errors in the administration of therapy Purpose: To elucidate the distinction between HFMD and Primary varicella zoster infection. Case: An 8 year-old male sought treatment complaining of ulcers on the upper maxillary gingiva followed by the appearance of itchy and painful lesions affecting the nose, upper lip, hands and feet. The patient’s mother reported his history of 39oC fever followed by the development of red spots and ulcers on the face, hands and feet which caused itching. Clinically, it is similar to Primary varicella zoster infection which can affect any part of the body. The patient only used an immunomodulator once a day and was actively seeking available healthcare. Case management: Extraoral examination confirmed the presence of multiple erythematous vesicles and ulcers, 2 mm in diameter, which caused a sensation of itching around the nose and upper lip region. Multiple painful and itchy red macules and vesicles, 3-6 mm in diameter, appeared not only on the patient’s palms, back of the hands and feet. Intraoral examination of the right maxillary gingiva revealed multiple painful ulcers, 1-2 mm in diameter and yellowish in appearance, surrounded by erythema. The results of history-taking implied that no lesions appeared on other parts of the body. Conclusion: While these conditions share similar clinical manifestations, their contrasting etiologies require different treatments. The ultimate diagnosis can be determined clinically by the dentist, thereby preventing errors in the administration of therapy.

Sign in / Sign up

Export Citation Format

Share Document