scholarly journals AN IMPLANT FOR A VISUAL CORTICAL STIMULATOR

Author(s):  
Jonathan Coulombe ◽  
Yamu Hu ◽  
Jean-Franҫois Gervais ◽  
Mohammad Sawan

We present the design of an implantable micro-stimulator intended for a cortical visual prosthesis. The device is composed of several integrated modules to be assembled on a thin and flexible substrate providing placement flexibility on the cortex. The stimulator provides the user with significant usage flexibility, supplying biphasic current pulses using either monopolar or bipolar configurations, with single or distributed return electrode, and having a fixed or dynamic reference voltage. Monitoring of electrode-tissue interface condition is possible by measuring both simulation currents and voltages at any electrode for enhanced safety, and for enabling troubleshooting after implantation. In order to avoid erroneous stimulation to be executed, potentially caused by the implant's wireless transcutaneous power transfer, constant parameters stored in volatile memory are constantly monitored, and in case of data corruption, stimulation is automatically disabled. A power efficient recovery and regulation circuit is proposed for providing dual supply voltages. Also, a bidirectional wireless link with data rates up to 1.5 Mbps and 500 kbps, downlink and uplink respectively, has been designed for use with a 13.56 MHz carrier. Performances attained with a prototype, combined with the stimulator module's configurable communication protocol, are suitable for a cortical implant having more than 1000 stimulation sites, which is expected to be sufficient for providing blind subjects with a useful vision.

2005 ◽  
Vol 29 (3) ◽  
pp. 233-238 ◽  
Author(s):  
Jonathan Coulombe ◽  
Sylvain Carniguian ◽  
Mohamad Sawan

Author(s):  
Malcolm H. Smith

Many Internet of Things (IoT) applications use wireless links to communicate data back. Wireless system performance limits data rates. This data rate limit is what ultimately drives the location of computing resources—on the edge or in the cloud. To understand the limits of performance, it is instructive to look at the evolution of cellular and other radio systems. The emphasis will be on the RF front-end architectures and requirements as well as the modulation schemes used. Wireless sensor nodes will often need to run off batteries and be low-cost, and this will constrain the choice of wireless communications system. Generally cheap and power efficient radio front ends will not support high data rates which will mean that more computing will need to move to the edge. We will look at some examples to understand the choice of radio system for communication. We will also consider the use of radio in the sensor itself with a radar sensor system.


Author(s):  
Caroline A. Miller ◽  
Laura L. Bruce

The first visual cortical axons arrive in the cat superior colliculus by the time of birth. Adultlike receptive fields develop slowly over several weeks following birth. The developing cortical axons go through a sequence of changes before acquiring their adultlike morphology and function. To determine how these axons interact with neurons in the colliculus, cortico-collicular axons were labeled with biocytin (an anterograde neuronal tracer) and studied with electron microscopy.Deeply anesthetized animals received 200-500 nl injections of biocytin (Sigma; 5% in phosphate buffer) in the lateral suprasylvian visual cortical area. After a 24 hr survival time, the animals were deeply anesthetized and perfused with 0.9% phosphate buffered saline followed by fixation with a solution of 1.25% glutaraldehyde and 1.0% paraformaldehyde in 0.1M phosphate buffer. The brain was sectioned transversely on a vibratome at 50 μm. The tissue was processed immediately to visualize the biocytin.


Author(s):  
William L. Hickerson ◽  
George M. Slugocki ◽  
Reuben L. Thaker ◽  
Robert Duncan ◽  
John F. Bishop ◽  
...  

PIERS Online ◽  
2010 ◽  
Vol 6 (2) ◽  
pp. 105-108 ◽  
Author(s):  
Haipeng Lu ◽  
Jing Yang ◽  
Longjiang Deng

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