Allergen Specific IgG Subclass Antibody Response in Hyposensitization with Dermatophagoides Pteronyssinus Extract

1987 ◽  
Vol 8 (6) ◽  
pp. 417-421 ◽  
Author(s):  
E. A. Pastorello ◽  
C. Incorvaia ◽  
A. Gerosa ◽  
D. Vassellatti ◽  
M. Italia ◽  
...  
Keyword(s):  
Antibody Response ◽  
Dermatophagoides Pteronyssinus ◽  
Igg Subclass ◽  
Specific Igg

scholarly journals Toxoplasma-SPECIFIC IgG SUBCLASS ANTIBODY RESPONSE IN CEREBROSPINAL FLUID SAMPLES FROM PATIENTS WITH CEREBRAL TOXOPLASMOSIS

2015 ◽  
Vol 57 (5) ◽  
pp. 439-442
Author(s):  
Fernanda S. NASCIMENTO ◽  
Lisandra A. SUZUKI ◽  
Nilson BRANCO ◽  
Regina M.B. FRANCO ◽  
Paula D. ANDRADE ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Immune System ◽  
Toxoplasma Gondii ◽  
Antibody Response ◽  
Igg Subclasses ◽  
Igg Subclass ◽  
Cerebral Toxoplasmosis ◽  
Arithmetic Means ◽  
Antigen Preparation ◽  
Specific Igg

SUMMARY Cerebral toxoplasmosis can be highly debilitating and occasionally fatal in persons with immune system deficiencies. In this study, we evaluated the Toxoplasma gondii-specific IgG subclass antibody response in 19 cerebrospinal fluid (CSF) samples from patients with cerebral toxoplasmosis who had a positive IgG anti-T. gondii ELISA standardized with a cyst antigen preparation. There were no significant differences between the rates of positivity and the antibody concentrations (arithmetic means of the ELISA absorbances, MEA) for IgG1 and IgG2, but the rates of positivity and MEA values for these two IgG subclasses were significantly higher than those for IgG3 and IgG4. The marked IgG2 response in CSF from patients with cerebral toxoplasmosis merits further investigation.

Persistence of HBV-DNA in children with chronic hepatitis B who seroconverted to anti-HBs antibodies after interferon-α therapy: correlation with specific IgG subclass responses to HBsAg

2005 ◽  
Vol 42 (4) ◽  
pp. 486-490 ◽  
Author(s):  
Hanna Gregorek ◽  
Katarzyna Dzierżanowska-Fangrat ◽  
Marek Woynarowski ◽  
Paulina Jóźwiak ◽  
Ewa Witkowska-Vogtt ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Hbv Dna ◽  
Interferon Α ◽  
Igg Subclass ◽  
Specific Igg

scholarly journals Rubella-specific IgG subclass concentrations in sera using an enzyme-linked immunosorbent assay (ELISA): the effect of different sources of rubella antigen

1988 ◽  
Vol 101 (3) ◽  
pp. 599-604 ◽  
Author(s):  
H. I. J Thomas ◽  
P. Morgan-Capner
Keyword(s):  
Immunosorbent Assay ◽  
Enzyme Linked Immunosorbent Assay ◽  
Igg Subclass ◽  
Human Igg ◽  
Discrepant Result ◽  
Specific Igg ◽  
Antigen A ◽  
Different Sources ◽  
Positive Results

SUMMARYFive rubella antigens were evaluated in an antiglobulin enzyme-linked immunosorbent assay for rubella-specific IgG subclass antibody. One monoclonal anti-human IgG subclass antibody was used for each of IgG1, IgG2and IgG4, but two were compared for IgG3. A total of 101 sera were tested from cases of rubella in the distant past and from cases of primary rubella, reinfection and following immunization. Only one serum gave a discrepant result for specific IgG1, being positive with only one rubella antigen, a commercially prepared antigen coated on to microtitre wells (Enzygnost; Behringwerke). No sera contained detectable specific IgG2. Only four sera contained specific IgG4, and this was detectable only with Enzygnost antigen. For specific IgG3little difference was observed between the two monoclonal anti-human IgG3subclass antibodies; only two very weakly positive sera gave discrepant results. However, varying results were obtained for specific IgG3with the different antigens. Enzygnost gave more positive results for specific IgG3with most categories of sera.It is concluded that the differences between various reports of the rubella-specific IgG subclass profile cannot be explained entirely by the use of different rubella antigens.

scholarly journals Antibody response to BTN162b2 mRNA vaccination in naïve versus SARS-CoV-2 infected subjects with and without waning immunity

2021 ◽  
Author(s):  
Donato Zipeto ◽  
Luca Dalle Carbonare ◽  
Maria Teresa Valenti ◽  
Zeno Bisoffi ◽  
Chiara Piubelli ◽  
...  
Keyword(s):  
Antibody Response ◽  
Vaccine Dose ◽  
Antibody Responses ◽  
Serum Neutralization ◽  
Iga Response ◽  
Waning Immunity ◽  
Specific Igg

Abstract We profiled antibody responses in a cohort of recipients of the BTN162b2 mRNA vaccine who were either immunologically naïve (n=50) or had been previously infected with SARS-CoV-2 (n=51). Of the previously infected, 25 and 26 were infected during the first and second pandemic waves in Italy, respectively; the majority of those from the first wave had corresponding waning immunity with low to undetectable levels of anti-S antibodies and low anti-N antibodies. We observed in recipients who had been previously infected that spike-specific IgG and pseudovirus neutralization titers were rapidly recalled by a single vaccine dose to higher levels than those in naïve recipients after the second vaccine dose, irrespective of waning immunity. In all recipients, a single vaccine dose was sufficient to induce a potent IgA response that was not associated with serum neutralization titers.

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